Results 181 to 190 of about 38,957 (260)
Studies of Isonitrile Synthases Help Elucidate the Mechanism of Isonitrile Installation. [PDF]
Chen TY +5 more
europepmc +1 more source
ABSTRACT Sacubitril/valsartan (Sac/Val) has emerged as an effective compound with myocardium‐protective functions in experimental and clinical trials for heart failure. This study investigated the function of Sac/Val in hypertensive heart disease (HHD) and explored the underlying mechanism.
Yan‐Jun Yang, Jiu‐Sheng Li
wiley +1 more source
Editorial: Plant molecular farming for biopharmaceutical production and beyond. [PDF]
Wang KY, Guo Y.
europepmc +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
Draft genome sequence of <i>Nocardia</i> anissiorum JW2 isolated from soil with high antimicrobial resistance to antimicrobial compounds secreted by <i>Streptomyces spp</i>. [PDF]
Anissi J.
europepmc +1 more source
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
Endogenous modulators in lung cancer. [PDF]
Patel N, Patel V, Surani S.
europepmc +1 more source
Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei +7 more
wiley +1 more source
Fungal Chitin Synthases: Structure, Function, and Regulation. [PDF]
Brain L +3 more
europepmc +1 more source
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source

