Results 101 to 110 of about 483,286 (273)

Breakthrough Solution for Antimicrobial Resistance Detection: Surface‐Enhanced Raman Spectroscopy‐based on Artificial Intelligence

Advanced Materials Interfaces, EarlyView., 2023
This review discusses the use of Surface‐Enhanced Raman Spectroscopy (SERS) combined with Artificial Intelligence (AI) for detecting antimicrobial resistance (AMR). Various SERS studies used with AI techniques, including machine learning and deep learning, are analyzed for their advantages and limitations.
Zakarya Al‐Shaebi, Munevver Akdeniz, Awel Olsido Ahmed, Mine Altunbek, Omer Aydin   +4 more
wiley   +1 more source

Synthesis of Novel Arginine Building Blocks with Increased Lipophilicity Compatible with Solid-Phase Peptide Synthesis. [PDF]

Molecules, 2023
Glavaš M, Gitlin-Domagalska A, Ptaszyńska N, Starego D, Freza S, Dębowski D, Helbik-Maciejewska A, Łęgowska A, Gilon C, Rolka K.   +9 more
europepmc   +1 more source

t-Amyloxycarbonyl as a New Protecting Group in Peptide Synthesis. II. Synthesis of a Hexapeptide Amide Related to Eledoisin by thet-Amyloxycarbonyl Method [PDF]

, 1966
Shumpei Sakakibara, Masahiko Fujino
openalex   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

Electrostatic Ratchet for Successive Peptide Synthesis in Nonribosomal Molecular Machine RimK. [PDF]

J Am Chem Soc, 2023
Ohnuki J, Arimura Y, Kono T, Kino K, Kurumizaka H, Takano M.   +5 more
europepmc   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Suppression of alpha-carbon racemization in peptide synthesis based on a thiol-labile amino protecting group. [PDF]

Nat Commun, 2023
Zhou Y, Li H, Huang Y, Li J, Deng G, Chen G, Xi Z, Zhou C.   +7 more
europepmc   +1 more source

THE ASYMMETRIC SYNTHESIS OF PEPTIDE BONDS BY THE ACTION OF FICIN

, 1950
Senji Utzino, Toshio Yoneya
openalex   +2 more sources

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Accelerated Multiphosphorylated Peptide Synthesis. [PDF]

Org Process Res Dev, 2022
Grunhaus D, Molina ER, Cohen R, Stein T, Friedler A, Hurevich M.   +5 more
europepmc   +1 more source