Results 131 to 140 of about 483,286 (273)

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

A Practical Peptide Synthesis Workflow Using Amino-Li-Resin. [PDF]

open access: yesMethods Protoc, 2022
Akintayo DC   +4 more
europepmc   +1 more source

Systematic Comparison of Commercial Uranyl‐Alternative Stains for Negative‐ and Positive‐Staining Transmission Electron Microscopy of Organic Specimens

open access: yesAdvanced Healthcare Materials, EarlyView.
Negative‐ and positive‐staining TEM is essential for rapid nanometer‐resolution characterization of organic specimens ranging from nanoparticles to cells. Uranyl salts are widely used negative‐/positive‐stains but are radioactive and highly toxic to users and the environment.
Vera M. Kissling   +4 more
wiley   +1 more source

Rapid peptide synthesis using a methylimidazolium sulfinyl fluoride salt. [PDF]

open access: yesCommun Chem
Lai J   +4 more
europepmc   +1 more source

Mechanistic Study of Diketopiperazine Formation during Solid-Phase Peptide Synthesis of Tirzepatide. [PDF]

open access: yesACS Omega, 2022
Wang J   +11 more
europepmc   +1 more source

Functionalized Cerium Oxide Nanoparticles Enhance Penetration into Melanoma Spheroids In Vivo through Angiogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Melanoma cell spheroid engraftment is optimized in the chicken chorioallantoic membrane overcoming the complexity of other in vivo models. Using this model, greater penetration of cerium oxide nanoparticles (nanoceria) functionalized with heparin in spheroids is observed via enhancement of vascularization than nanoceria alone.
Lu Fu   +5 more
wiley   +1 more source

Rapid synthesis of glycosylated insulins by flow-based peptide synthesis. [PDF]

open access: yesChem Sci
Maki Y   +8 more
europepmc   +1 more source

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