Results 241 to 250 of about 483,286 (273)
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The synthesis of glyconyl peptides
Archives of Biochemistry and Biophysics, 1959Abstract Using N,N′ -dicyclohexylcarbodiimide as a coupling agent, the present study reports the successful synthesis of pentaacetyl d -gluconyl glycine ethyl ester, pentaacetyl d -gluconyl glycylglycine ethyl ester, pentaacetyl d -gluconyl tyrosine ethyl ester, pentaacetyl d -galactonyl glycine ethyl ester, and pentaacetyl d -galactonyl ...
Lawrence J. Schroeder +2 more
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Nature, 1965
The value of synthetic organic chemistry to our understanding of the action of hypotensive peptides, and other biologically active peptides, has been well demonstrated. For example, the structure of bradykinin was originally established not only by degradative procedures (Elliott et al., 1960) but also by synthesis (Boissonnas et al., 1960).
John Morrow Stewart, R. B. Merrifield
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The value of synthetic organic chemistry to our understanding of the action of hypotensive peptides, and other biologically active peptides, has been well demonstrated. For example, the structure of bradykinin was originally established not only by degradative procedures (Elliott et al., 1960) but also by synthesis (Boissonnas et al., 1960).
John Morrow Stewart, R. B. Merrifield
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1957
Publisher Summary The chapter presents the general aspects of peptide synthesis and deals with the manipulation of the various amino-protecting groups, the handling of the esters, and the numerous methods of condensation. Most peptide syntheses proceed according to the classical scheme in which the amino group of a peptide ester or an amino acid ...
Murray Goodman, G.W. Kenner
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Publisher Summary The chapter presents the general aspects of peptide synthesis and deals with the manipulation of the various amino-protecting groups, the handling of the esters, and the numerous methods of condensation. Most peptide syntheses proceed according to the classical scheme in which the amino group of a peptide ester or an amino acid ...
Murray Goodman, G.W. Kenner
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, 2010 In the last chapter we have seen how to determine the sequence of a protein. For many purposes it would be useful to synthesise proteins of a given sequence. The solid-phase approach of Merrifield (Fig. 31.1) serves this purpose.
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2003
Peptides are required for many different aspects of biotechnology. Since DNA sequences are generally functional only in the protein for which they code, the explosion in sequences that are known has led to an increase in the requirement for synthetic peptides.
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Peptides are required for many different aspects of biotechnology. Since DNA sequences are generally functional only in the protein for which they code, the explosion in sequences that are known has led to an increase in the requirement for synthetic peptides.
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ChemInform Abstract: Synthesis of Lipidated Peptides
ChemInform, 2013AbstractReview: 14 refs.
Federica Rosi, Gemma Triola
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2018
Synthetic mono-ADPr-peptides are useful for structural, biochemical, and proteomics studies. We describe here a protocol for the preparation of mono-ADPr-peptides based on a fairly standard Fmoc-based solid-phase synthesis. Phosphoribosylated precursor building blocks are introduced into the peptide chain on solid-phase and subsequently converted to ...
Jim Voorneveld +2 more
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Synthetic mono-ADPr-peptides are useful for structural, biochemical, and proteomics studies. We describe here a protocol for the preparation of mono-ADPr-peptides based on a fairly standard Fmoc-based solid-phase synthesis. Phosphoribosylated precursor building blocks are introduced into the peptide chain on solid-phase and subsequently converted to ...
Jim Voorneveld +2 more
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ChemInform Abstract: Synthesis of Prenylated Peptides and Peptide Esters
ChemInform, 1997AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Fred Naider, Jeffrey M. Becker
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The Synthesis of Peptides [PDF]
, 1949 Publisher Summary The usefulness of peptide synthesis to protein chemistry is abundant. Modern methods of peptide synthesis allows the preparation of special peptides of low molecular weight and known chemical structure for use as models in the examination of several physical and chemical properties of proteins.
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Synthesis of peptide analogues using the multipin peptide synthesis method
Analytical Biochemistry, 1991Modification of the multipin peptide synthesis method which allows the simultaneous synthesis of large numbers of different peptide analogues is described. Peptides were assembled on polyethylene pins derivatized with a 4-(beta-alanyloxymethyl)benzoate (beta-Ala-HMB) handle. For comparative purposes, peptides were also assembled on the diketopiperazine-
Andrew M. Bray +4 more
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