Results 41 to 50 of about 186,549 (302)
Marine Drugs, 2020 κ-Conotoxin-PVIIA (κ-PVIIA) is a potassium-channel blocking peptide from the venom of the fish-hunting snail, Conus purpurascens, which is essential for quick prey’s excitotoxic immobilization.
David Naranjo, Ignacio Díaz-Franulic
doaj +1 more source
Human Peptides α-Defensin-1 and -5 Inhibit Pertussis Toxin
Toxins, 2021 Bordetella pertussis causes the severe childhood disease whooping cough, by releasing several toxins, including pertussis toxin (PT) as a major virulence factor.
Carolin Kling +3 more
doaj +1 more source
Biologically Active Peptides in Physalia Toxin.
Experimental Biology and Medicine, 1961 Summary and conclusionsThe crude toxin of Physalia nematocysts withstands lyophilization without significant loss of toxicity. Physalia toxin may be separated into component peptides by one-dimensional chromatography in 80% aqueous n-propanol. Each of the resultant peptides retains considerable toxicity for the fiddler crab, Uca pugilator.
C E, LANE, B W, COURSEN, K, HINES
openaire +2 more sources
Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of E.coli
, 2014 Background: Animal neurotoxin peptides are valuable probes for investigating ion channel structure/function relationships and represent lead compounds for novel therapeutics and insecticides.
Cole, Ambrose R. +7 more
core +1 more source
Development of a malaria vaccine candidate based on virosome technology [PDF]
, 2006 Malaria is an infectious disease caused by protozoan pathogens of the genus Plasmodium. The most important species affecting humans is P. falciparum transmitted by the bite of female Anopheles mosquitoes during a blood meal.
Okitsu, Shinji Lukas
core +1 more source
Peptide-Protein Conjugation and Characterization to Develop Vaccines for Group A Streptococcus
, 2021 Peptide conjugates have been widely used for developing vaccines that prevent common bacterial infections for which peptides alone are either ineffective or provide only short-term protection. Among several carrier proteins, diphtheria toxoid and CRM197 (
Manisha Pandey +5 more
core +1 more source
Toxin diversity revealed by a transcriptomic study of Ornithoctonus huwena. [PDF]
PLoS ONE, 2014 Spider venom comprises a mixture of compounds with diverse biological activities, which are used to capture prey and defend against predators. The peptide components bind a broad range of cellular targets with high affinity and selectivity, and appear to
Yiya Zhang +10 more
doaj +1 more source
Carcinogenicity of nitrate, nitrite, and cyanobacterial peptide toxins [PDF]
The Lancet Oncology, 2006 In June, 2006, 19 scientists from eight countries met at the International Agency for Research on Cancer (IARC) in Lyon, France, to assess the carcinogenicity of ingested nitrate and nitrite, and the cyanobacterial peptide toxins microcystin-LR and nodularins.
Grosse, Yann +5 more
openaire +3 more sources
Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways [PDF]
, 2011 Background: The small molecule Eeyarestatin I (ESI) inhibits the endoplasmic reticulum (ER)-cytosol dislocation and subsequent degradation of ERAD (ER associated protein degradation) substrates.
Aletrari, Mina-Olga +28 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source