Results 21 to 30 of about 793,047 (255)

Isolation and cDNA cloning of four peptide toxins from the sea anemone Heteractis aurora [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases
Background: Sea anemones are well known to contain multiple peptide toxins. However, of more than 1100 species of sea anemones distributed worldwide, only a little over 50 have been studied for peptide toxins.
Tomohiro Homma, Masami Ishida, Yuji Nagashima, Kazuo Shiomi   +3 more
doaj   +1 more source

An in silico insight into novel therapeutic interaction of LTNF peptide-LT10 and design of structure based peptidomimetics for putative anti-diabetic activity. [PDF]

PLoS ONE, 2015
Lethal Toxin Neutralizing Factor (LTNF) obtained from Opossum serum (Didephis virginiana) is known to exhibit toxin-neutralizing activity for envenomation caused by animals, plants and bacteria.
Sonali Gopichand Chavan, Deepti Dileep Deobagkar   +1 more
doaj   +1 more source

Molecular Diversity of Peptide Toxins in the Venom of Spider Heteropoda pingtungensis as Revealed by cDNA Library and Transcriptome Sequencing Analysis

Toxins, 2022
The venoms of toxic animals are chemical pools composed of various proteins, peptides, and small organic molecules used for predation and defense, in which the peptidic toxins have been intensively pursued mining modulators targeting disease-related ion ...
Qingyi Liao, Xiangjin Kong, Guoqing Luo, Xiangyue Wu, Yinping Li, Qicai Liu, Cheng Tang, Zhonghua Liu   +7 more
doaj   +1 more source

Comparative genomics of Shiga toxin encoding bacteriophages [PDF]

, 2012
Background Stx bacteriophages are responsible for driving the dissemination of Stx toxin genes (stx) across their bacterial host range. Lysogens carrying Stx phages can cause severe, lifethreatening disease and Stx toxin is an integral virulence factor.
Alan J McCarthy, Darby Alistair C, Alistair C Darby, Allison Heather E, Rooks David J, Rooks, David, Smith, Darren, Paul CM Fogg, Thomson, Nicholas, David J Rooks, Smith Darren L, McCarthy Alan J, McCarthy, Alan, Heather E Allison, Darren L Smith, Allison, Heather, Fogg Paul CM, Nick R Thomson, Fogg, Paul, Darby, Alistair, Thomson Nick R   +20 more
core   +1 more source

A video of best practice recommendations for making botulinum toxin therapy safe during the COVID-19 pandemic

, 2021
The physician and patient come into close contact during botulinum toxin treatments, increasing the chances of COVID-19 infection. Therefore, it is essential to use an effective injection method that can prevent infection with SARS-CoV-2 virus.
Altavista, Maria Concetta, Sacco, Simona, Eleopra, Roberto, talian Botulinum Toxin Network -study group of Italian Society of Neurology, Bono, Francesco   +4 more
core   +1 more source

Structure-Based Prototype Peptides Targeting the Pseudomonas aeruginosa Type VI Secretion System Effector as a Novel Antibacterial Strategy

Frontiers in Cellular and Infection Microbiology, 2017
The type VI secretion system (T6SS) secretes numerous toxins for bacteria-bacteria competition. TplE is a newly identified trans-kingdom toxin secreted by the T6SS in Pseudomonas aeruginosa, while TplEi neutralizes the toxic effect of TplE to protect ...
Xiaopan Gao, Zhixia Mu, Bo Qin, Yicheng Sun, Sheng Cui   +4 more
doaj   +1 more source

Assembling an arsenal, the scorpion way

BMC Evolutionary Biology, 2008
Background For survival, scorpions depend on a wide array of short neurotoxic polypeptides. The venoms of scorpions from the most studied group, the Buthida, are a rich source of small, 23–78 amino acid-long peptides, well packed by either three or four ...
Mishmar Dan, Bar-Shalom Adi, Kozminsky-Atias Adi, Zilberberg Noam   +3 more
doaj   +1 more source

Structure of the voltage-gated potassium channel KV1.3: Insights into the inactivated conformation and binding to therapeutic leads

Channels, 2023
The voltage-gated potassium channel KV1.3 is an important therapeutic target for the treatment of autoimmune and neuroinflammatory diseases. The recent structures of KV1.3, Shaker-IR (wild-type and inactivating W434F mutant) and an inactivating mutant of
K. George Chandy, Karoline Sanches, Raymond S. Norton   +2 more
doaj   +1 more source

Structural insights into Clostridium perfringens delta toxin pore formation [PDF]

, 2013
Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which following the
Claire E Naylor, Gibert, M., Popoff, Michel, Popoff, M.R., Motta, A., Michel R Popoff, Christos G Savva, Jessica Huyet (425370), Ajit K. Basak (425373), Michel R. Popoff, Huyet Jessica, Naylor, Claire E., Basak Ajit K., Gibert, Maryse, Basak, Ajit,, Claire E. Naylor (425371), Ajit K. Basak, Savva Christos G., Michel R. Popoff (147963), Motta, Andrea, Claire E. Naylor, Basak, Ajit, K, Huyet, Jessica, Basak, Ajit K., Savva, Christos, G, Popoff Michel R., Naylor, Claire, E, Naylor Claire E., Ajit K Basak, Christos G. Savva (425372), Gibert Maryse, Naylor, Claire,, Savva, Christos,, Christos G. Savva, Maryse Gibert, Jessica Huyet, Maryse Gibert (269234), Savva, Christos G.   +37 more
core   +1 more source

Inhibition of development of Shiga toxin-converting bacteriophages by either treatment with citrate or amino acid starvation [PDF]

, 2012
Objectives: Shiga toxin–producing Escherichia coli (STEC) are pathogenic strains, whose virulence depends on induction of Shiga toxin–converting prophages and their subsequent lytic development.
Bożena Nejman-Faleńczyk, Grzegorz Węgrzyn, Maciąg, Monika, Alicja Wegrzyn, Węgrzyn, Alicja, Węgrzyn, Grzegorz, Golec, Piotr, Nejman-Faleńczyk, Bożena, Monika Maciąg, Piotr Golec   +9 more
core   +2 more sources