Results 11 to 20 of about 260,045 (204)

Candidalysin is a fungal peptide toxin critical for mucosal infection. [PDF]

Nature, 2016
Moyes DL, Wilson D, Richardson JP, Mogavero S, Tang SX, Wernecke J, Höfs S, Gratacap RL, Robbins J, Runglall M, Murciano C, Blagojevic M, Thavaraj S, Förster TM, Hebecker B, Kasper L, Vizcay G, Iancu SI, Kichik N, Häder A, Kurzai O, Luo T, Krüger T, Kniemeyer O, Cota E, Bader O, Wheeler RT, Gutsmann T, Hube B, Naglik JR.   +29 more
europepmc   +2 more sources

Identification of Novel Toxin Genes from the Stinging Nettle Caterpillar Parasa lepida (Cramer, 1799): Insights into the Evolution of Lepidoptera Toxins

Insects, 2021
Many animal species can produce venom for defense, predation, and competition. The venom usually contains diverse peptide and protein toxins, including neurotoxins, proteolytic enzymes, protease inhibitors, and allergens.
Natrada Mitpuangchon, Kwan Nualcharoen, Singtoe Boonrotpong, Patamarerk Engsontia   +3 more
doaj   +1 more source

Characterization and evaluation of the enzymatic activity of tetanus toxin submitted to cobalt-60 gamma radiation [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2021
Background Tetanus toxin blocks the release of the inhibitory neurotransmitters in the central nervous system and causes tetanus and its main form of prevention is through vaccination.
Giselle Pacifico Sartori, Andréa da Costa, Fernanda Lúcio dos Santos Macarini, Douglas Oscar Ceolin Mariano, Daniel Carvalho Pimenta, Patrick Jack Spencer, Luiz Henrique da Silva Nali, Andrés Jimenez Galisteo Jr.   +7 more
doaj   +1 more source

Expression, Purification, and Biophysical Characterization of a Secreted Anthrax Decoy Fusion Protein in Nicotiana benthamiana. [PDF]

, 2017
Anthrax toxin receptor-mediated drug development for blocking anthrax toxin action has received much attention in recent decades. In this study, we produced a secreted anthrax decoy fusion protein comprised of a portion of the human capillary ...
Dandekar, Abhaya M, Duhra-Gill, Sifti, Kailemia, Muchena J, Karuppanan, Kalimuthu, Lebrilla, Carlito B, McDonald, Karen A, Nandi, Somen, Phu, My L, Rodriguez, Raymond L   +8 more
core   +2 more sources

Peptides as toxins/defensins [PDF]

Amino Acids, 2010
Sao Paulo State Univ, UNESP, Inst Biosci Rio Claro, Dept Biol,Ctr Study Social Insects CEIS, BR-13506900 Rio Claro, SP ...
openaire   +3 more sources

Cloning and Characterization of a Cyclic Peptide Synthetase Gene from Alternaria alternata Apple Pathotype Whose Product Is Involved in AM-Toxin Synthesis and Pathogenicity

Molecular Plant-Microbe Interactions, 2000
Alternaria alternata apple pathotype causes Alternaria blotch of susceptible apple cultivars through the production of a cyclic peptide host-specific toxin, AM-toxin.
R. D. Johnson, L. Johnson, Y. Itoh, M. Kodama, H. Otani, K. Kohmoto   +5 more
doaj   +1 more source

High yield production and refolding of the double-knot toxin, an activator of TRPV1 channels. [PDF]

PLoS ONE, 2012
A unique peptide toxin, named double-knot toxin (DkTx), was recently purified from the venom of the tarantula Ornithoctonus huwena and was found to stably activate TRPV1 channels by targeting the outer pore domain.
Chanhyung Bae, Jeet Kalia, Inhye Song, JeongHeon Yu, Ha Hyung Kim, Kenton J Swartz, Jae Il Kim   +6 more
doaj   +1 more source

An in silico insight into novel therapeutic interaction of LTNF peptide-LT10 and design of structure based peptidomimetics for putative anti-diabetic activity. [PDF]

PLoS ONE, 2015
Lethal Toxin Neutralizing Factor (LTNF) obtained from Opossum serum (Didephis virginiana) is known to exhibit toxin-neutralizing activity for envenomation caused by animals, plants and bacteria.
Sonali Gopichand Chavan, Deepti Dileep Deobagkar   +1 more
doaj   +1 more source

Molecular Diversity of Peptide Toxins in the Venom of Spider Heteropoda pingtungensis as Revealed by cDNA Library and Transcriptome Sequencing Analysis

Toxins, 2022
The venoms of toxic animals are chemical pools composed of various proteins, peptides, and small organic molecules used for predation and defense, in which the peptidic toxins have been intensively pursued mining modulators targeting disease-related ion ...
Qingyi Liao, Xiangjin Kong, Guoqing Luo, Xiangyue Wu, Yinping Li, Qicai Liu, Cheng Tang, Zhonghua Liu   +7 more
doaj   +1 more source

Isolation and cDNA cloning of four peptide toxins from the sea anemone Heteractis aurora [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases
Background: Sea anemones are well known to contain multiple peptide toxins. However, of more than 1100 species of sea anemones distributed worldwide, only a little over 50 have been studied for peptide toxins.
Tomohiro Homma, Masami Ishida, Yuji Nagashima, Kazuo Shiomi   +3 more
doaj   +1 more source