Results 121 to 130 of about 24,252 (260)

Long‐Term Impact of Bariatric Surgery and Dietary Interventions on Weight Loss, Physical Activity, and Food Preferences

open access: yesObesity, EarlyView.
ABSTRACT Objective This study aimed to examine changes in dietary intake, physical activity, appetite, and weight following laparoscopic adjustable gastric banding (LAGB), sleeve gastrectomy (SG), Roux‐en‐Y gastric bypass (RYGB), and dietary intervention in adults with severe obesity.
Michael Do   +5 more
wiley   +1 more source

A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia

open access: yesThe Journal of Pathology, EarlyView.
Abstract The cellular composition and disease susceptibilities of the distinct zones of the human prostate remain incompletely understood. Benign prostatic hyperplasia (BPH) is a common condition that causes widespread morbidity and is nearly exclusively localized to the transition zone (TZ).
Rulin Wang   +20 more
wiley   +1 more source

Information‐Theoretic Framework for Allosteric Communication Pathway Prediction From Protein Structure

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Allosteric communication is fundamental to the function of proteins, but identifying the residue‐level pathways through which signals travel and their directionality is still a major challenge. Here we present a multi‐metric information‐theoretic framework that identifies candidate allosteric communication pathways from a single protein ...
Aysima Hacisuleyman, Dirk Fasshauer
wiley   +1 more source

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu   +6 more
wiley   +1 more source

Astragaloside IV Restores Autophagy and Inhibits Apoptosis for Podocyte Protection in Diabetic Nephropathy by Inhibiting Notch1 Signaling via SIRT6‐Mediated Deacetylation

open access: yesPhytotherapy Research, EarlyView.
AS‐IV binds to SIRT6 and promotes H3K9 deacetylation at the Notch1 promoter, inhibiting gene transcription (Created with BioGDP.com). ABSTRACT Astragaloside IV (AS‐IV) has demonstrated efficacy in ameliorating proteinuria and attenuating renal tubular damage in preclinical diabetic nephropathy (DN) models.
Qiyu Yue   +11 more
wiley   +1 more source

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