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Marine Invertebrate Peptides: Antimicrobial Peptides [PDF]
Frontiers in Microbiology, 2021 Antimicrobial peptides are an important component of many organisms’ innate immune system, with a good inhibitory or killing effect against the invading pathogens. As a type of biological polypeptide with natural immune activities, antimicrobial peptides have a broad spectrum of antibacterial, antiviral, and antitumor activities.
Ran Wu +9 more
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SignalP 6.0 predicts all five types of signal peptides using protein language models
Nature Biotechnology, 2022 Signal peptides (SPs) are short amino acid sequences that control protein secretion and translocation in all living organisms. SPs can be predicted from sequence data, but existing algorithms are unable to detect all known types of SPs.
Felix Teufel +9 more
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Therapeutic peptides: current applications and future directions
Signal Transduction and Targeted Therapy, 2022 Peptide drug development has made great progress in the last decade thanks to new production, modification, and analytic technologies. Peptides have been produced and modified using both chemical and biological methods, together with novel design and ...
Lei Wang +8 more
semanticscholar +1 more source
Scientific Reports, 2021 To evaluate the effect of age and parity on maternal cardiac diastolic function in second trimester among pregnant women with normal left ventricular ejection fraction. To analyze the correlation between impaired diastolic function and pre-eclampsia.
Dan Zhu +5 more
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Food Production, Processing and Nutrition, 2021 Rising consumer concerns with synthetic drugs to treat non-communicable diseases (NCDs) have promoted a shift towards using natural biological active constituents that offer similar health benefits.
U. C. Urbizo-Reyes +2 more
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Molecules, 2021 A new aliphatic acid, compound 1, together with six known metabolites, including nonactic acid (2), homononactic acid (3), ethyl homononactate (4), homononactylhomononactate (5), valinomycin (6), and cyclo-(Pro-Leu) (7), was isolated from the culture ...
Shengsheng Lu +6 more
doaj +1 more source
Cyclic Peptides for Drug Development.
Angewandte Chemie, 2023 Cyclic peptides are fascinating molecules abundantly found in nature and exploited as molecular format for drug development as well as other applications, ranging from research tools to food additives.
Xinjian Ji +2 more
semanticscholar +1 more source
Vertebrate OTOP1 is also an alkali-activated channel
Nature Communications, 2023 pH sensation is critical for survival of vertebrates. Here, authors found six vertebrate OTOP1 channels that were highly conserved and directly activated by extracellular alkali.
Lifeng Tian +7 more
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Caveolin-Mediated Internalization of Fmoc-FF Nanogels in Breast Cancer Cell Lines
Pharmaceutics, 2023 Introduction: Hydrogel nanoparticles, also known as nanogels (NGs), have been recently proposed as alternative supramolecular vehicles for the delivery of biologically relevant molecules like anticancer drugs and contrast agents. The inner compartment of
Giovanni Smaldone +6 more
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Antimicrobial peptides: mechanism of action, activity and clinical potential
Military Medical Research, 2021 The management of bacterial infections is becoming a major clinical challenge due to the rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome antibiotic resistance, antimicrobial peptides (AMPs) that are produced from ...
Qiyu Zhang +9 more
semanticscholar +1 more source