Results 1 to 10 of about 1,654,252 (209)

Probing protein sequences as sources for encrypted antimicrobial peptides [PDF]

open access: yes, 2012
Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Alan Cooper   +8 more
core   +20 more sources

The correlation between maternal age, parity, cardiac diastolic function and occurrence rate of pre-eclampsia

open access: yesScientific Reports, 2021
To evaluate the effect of age and parity on maternal cardiac diastolic function in second trimester among pregnant women with normal left ventricular ejection fraction. To analyze the correlation between impaired diastolic function and pre-eclampsia.
Dan Zhu   +5 more
doaj   +1 more source

Hairless canary seeds (Phalaris canariensis L.) as a potential source of antioxidant, antihypertensive, antidiabetic, and antiobesity biopeptides

open access: yesFood Production, Processing and Nutrition, 2021
Rising consumer concerns with synthetic drugs to treat non-communicable diseases (NCDs) have promoted a shift towards using natural biological active constituents that offer similar health benefits.
U. C. Urbizo-Reyes   +2 more
doaj   +1 more source

Secondary Metabolites with Cytotoxic Activities from Streptomyces sp. BM-8 Isolated from the Feces of Equusquagga

open access: yesMolecules, 2021
A new aliphatic acid, compound 1, together with six known metabolites, including nonactic acid (2), homononactic acid (3), ethyl homononactate (4), homononactylhomononactate (5), valinomycin (6), and cyclo-(Pro-Leu) (7), was isolated from the culture ...
Shengsheng Lu   +6 more
doaj   +1 more source

Vertebrate OTOP1 is also an alkali-activated channel

open access: yesNature Communications, 2023
pH sensation is critical for survival of vertebrates. Here, authors found six vertebrate OTOP1 channels that were highly conserved and directly activated by extracellular alkali.
Lifeng Tian   +7 more
doaj   +1 more source

Caveolin-Mediated Internalization of Fmoc-FF Nanogels in Breast Cancer Cell Lines

open access: yesPharmaceutics, 2023
Introduction: Hydrogel nanoparticles, also known as nanogels (NGs), have been recently proposed as alternative supramolecular vehicles for the delivery of biologically relevant molecules like anticancer drugs and contrast agents. The inner compartment of
Giovanni Smaldone   +6 more
doaj   +1 more source

Self-Supporting Hydrogels Based on Fmoc-Derivatized Cationic Hexapeptides for Potential Biomedical Applications

open access: yesBiomedicines, 2021
Peptide-based hydrogels (PHGs) are biocompatible materials suitable for biological, biomedical, and biotechnological applications, such as drug delivery and diagnostic tools for imaging.
Carlo Diaferia   +6 more
doaj   +1 more source

Amyloid-Like Aggregation in Diseases and Biomaterials: Osmosis of Structural Information

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
The discovery that the polypeptide chain has a remarkable and intrinsic propensity to form amyloid-like aggregates endowed with an extraordinary stability is one of the most relevant breakthroughs of the last decades in both protein/peptide chemistry and
Nicole Balasco   +4 more
doaj   +1 more source

Impact of Different Light Conditions on the Nitrogen, Protein, Colour, Total Phenolic Content and Amino Acid Profiles of Cultured Palmaria palmata

open access: yesFoods, 2023
The impact of different light conditions during culture on the nitrogen, protein, colour, total phenolic content (TPC) and amino acid profile of Palmaria palmata biomass was investigated. P. palmata was cultured using different light regimes, i.e., white
Anthony Temitope Idowu   +4 more
doaj   +1 more source

A theoretical analysis of secondary structural characteristics of anticancer peptides [PDF]

open access: yes, 2009
Here, cluster analysis showed that a database of 158 peptides formed 21 clusters based on net positive charge, hydrophobicity and amphiphilicity. In general these clusters showed similar median toxicities (p = 0.176) against eukaryotic cell lines and no ...
Bhatt, Tailap   +4 more
core   +1 more source

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