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Probing protein sequences as sources for encrypted antimicrobial peptides [PDF]
, 2012 Starting from the premise that a wealth of potentially biologically active peptides may lurk within proteins, we describe here a methodology to identify putative antimicrobial peptides encrypted in protein sequences.
Alan Cooper +8 more
core +20 more sources
Marine Invertebrate Peptides: Antimicrobial Peptides [PDF]
Frontiers in Microbiology, 2021 Antimicrobial peptides are an important component of many organisms’ innate immune system, with a good inhibitory or killing effect against the invading pathogens. As a type of biological polypeptide with natural immune activities, antimicrobial peptides have a broad spectrum of antibacterial, antiviral, and antitumor activities.
Ran Wu +9 more
openaire +3 more sources
C-peptide is a bioactive peptide [PDF]
Diabetologia, 2007 -ATPase.Nerveconductionvelocity.RedbloodcelldeformabilityAbbreviationsBB/Wor BioBreeding/WorcestereNOS endothelial nitric oxide synthaseICAM-1 intracellular adhesion molecule 1MAPK mitogen-activated protein kinaseNCV nerve conduction velocityDuring the past decade, reports from several laboratorieshave focused on the physiological effects of C-peptide ...
John Wahren, Hans Jörnvall, K. Ekberg
openaire +3 more sources
, 2021 Peptides produced by hydrolysis of milk proteins during technological processes and storage greatly influence the functional and biological properties of dairy products. This chapter deals with the main analytical techniques for milk peptide analysis.
Recio, Isidra +3 more
openaire +2 more sources
A theoretical analysis of secondary structural characteristics of anticancer peptides [PDF]
, 2009 Here, cluster analysis showed that a database of 158 peptides formed 21 clusters based on net positive charge, hydrophobicity and amphiphilicity. In general these clusters showed similar median toxicities (p = 0.176) against eukaryotic cell lines and no ...
Bhatt, Tailap +4 more
core +1 more source
Analysis of iodinated quorum sensing peptides by LC-UV/ESI ion trap mass spectrometry [PDF]
, 2018 Five different quorum sensing peptides (QSP) were iodinated using different iodination techniques. These iodinated peptides were analyzed using a C-18 reversed phase HPLC system, applying a linear gradient of water and acetonitrile containing 0.1% (m/v ...
De Spiegeleer, Bart +5 more
core +2 more sources
Peptides, Antibodies, Peptide Antibodies and More [PDF]
International Journal of Molecular Sciences, 2019 The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed to any desired target, which illustrates their versatile nature and broad spectrum of use as illustrated by numerous applications of ...
Nicole Trier, Paul Hansen, Gunnar Houen
openaire +5 more sources
Peptide Stapling Applied to Antimicrobial Peptides
Antibiotics, 2023 Antimicrobial peptides (AMPs) are considered a promising therapeutic approach against multi-drug resistant microorganisms. Besides their advantages, there are limitations to be overcome so that these molecules can become market competitive. One of the biggest limitations is proteolytic susceptibility, which could be overcome by structural modifications
Ana Laura Pereira Lourenço +4 more
openaire +3 more sources
Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides [PDF]
, 2018 A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides.
Gannon, Susan +7 more
core +1 more source
Trans-Bilayer Ion Conduction by Proline Containing Cyclic Hexapeptides and Effects of Amino Acid Substitutions on Ion Conducting Properties [PDF]
, 2010 Several ion channel forming cyclic peptides have been reported over the past two decades and various ion conducting mechanisms have been proposed. In this article, we report on amino acid substitutions in cyclic hexapeptides and their effects on the ion ...
Aoyagi, Haruhiko +6 more
core +2 more sources