Results 1 to 10 of about 2,020,211 (197)
SignalP 6.0 predicts all five types of signal peptides using protein language models
Nature Biotechnology, 2022 Signal peptides (SPs) are short amino acid sequences that control protein secretion and translocation in all living organisms. SPs can be predicted from sequence data, but existing algorithms are unable to detect all known types of SPs.
Felix Teufel +9 more
semanticscholar +1 more source
Therapeutic peptides: current applications and future directions
Signal Transduction and Targeted Therapy, 2022 Peptide drug development has made great progress in the last decade thanks to new production, modification, and analytic technologies. Peptides have been produced and modified using both chemical and biological methods, together with novel design and ...
Lei Wang +8 more
semanticscholar +1 more source
Scientific Reports, 2021 To evaluate the effect of age and parity on maternal cardiac diastolic function in second trimester among pregnant women with normal left ventricular ejection fraction. To analyze the correlation between impaired diastolic function and pre-eclampsia.
Dan Zhu +5 more
doaj +1 more source
Food Production, Processing and Nutrition, 2021 Rising consumer concerns with synthetic drugs to treat non-communicable diseases (NCDs) have promoted a shift towards using natural biological active constituents that offer similar health benefits.
U. C. Urbizo-Reyes +2 more
doaj +1 more source
Molecules, 2021 A new aliphatic acid, compound 1, together with six known metabolites, including nonactic acid (2), homononactic acid (3), ethyl homononactate (4), homononactylhomononactate (5), valinomycin (6), and cyclo-(Pro-Leu) (7), was isolated from the culture ...
Shengsheng Lu +6 more
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Vertebrate OTOP1 is also an alkali-activated channel
Nature Communications, 2023 pH sensation is critical for survival of vertebrates. Here, authors found six vertebrate OTOP1 channels that were highly conserved and directly activated by extracellular alkali.
Lifeng Tian +7 more
doaj +1 more source
Caveolin-Mediated Internalization of Fmoc-FF Nanogels in Breast Cancer Cell Lines
Pharmaceutics, 2023 Introduction: Hydrogel nanoparticles, also known as nanogels (NGs), have been recently proposed as alternative supramolecular vehicles for the delivery of biologically relevant molecules like anticancer drugs and contrast agents. The inner compartment of
Giovanni Smaldone +6 more
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Antimicrobial peptides: mechanism of action, activity and clinical potential
Military Medical Research, 2021 The management of bacterial infections is becoming a major clinical challenge due to the rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome antibiotic resistance, antimicrobial peptides (AMPs) that are produced from ...
Qiyu Zhang +9 more
semanticscholar +1 more source
Biomedicines, 2021 Peptide-based hydrogels (PHGs) are biocompatible materials suitable for biological, biomedical, and biotechnological applications, such as drug delivery and diagnostic tools for imaging.
Carlo Diaferia +6 more
doaj +1 more source
A Global Review on Short Peptides: Frontiers and Perspectives
Molecules, 2021 Peptides are fragments of proteins that carry out biological functions. They act as signaling entities via all domains of life and interfere with protein-protein interactions, which are indispensable in bio-processes.
V. Apostolopoulos +24 more
semanticscholar +1 more source