Results 81 to 90 of about 2,703,759 (384)

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Designer lipid-like peptides [PDF]

open access: yes, 2011
A crucial bottleneck in membrane protein studies, particularly G-protein coupled receptors, is the notorious difficulty of finding an optimal detergent that can solubilize them and maintain their stability and function. Here we report rapid production of
Baaske, Philipp   +11 more
core   +1 more source

Antifungal Peptides [PDF]

open access: yesJournal of Fungi, 2021
Fungal infections represent an increasing public health crisis [...]
openaire   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Understanding Cell Penetration of Cyclic Peptides.

open access: yesChemical Reviews, 2019
Approximately 75% of all disease-relevant human proteins, including those involved in intracellular protein-protein interactions (PPIs), are undruggable with the current drug modalities (i.e., small molecules and biologics).
Patrick G. Dougherty   +2 more
semanticscholar   +1 more source

Peptides in proteins [PDF]

open access: yesJournal of Peptide Science, 2019
The protein universe as we know is composed of folded structures and intrinsic disordered regions. The latter may adopt structures upon interaction with binding partners. In addition, some proteins contain C‐terminal extensions which act as independent functional units in the context of the protein.
Benedikt Weber   +2 more
openaire   +4 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Lipid Vesicles Loaded with an HIV-1 Fusion Inhibitor Peptide as a Potential Microbicide

open access: yesPharmaceutics, 2020
The effective use of fusion inhibitor peptides against cervical and colorectal infections requires the development of sustained release formulations.
Elena Sánchez-López   +5 more
doaj   +1 more source

The roles of gut microbiota and its metabolites in diabetic nephropathy

open access: yesFrontiers in Microbiology, 2023
Diabetic nephropathy (DN) is a severe microvascular complication of diabetes, which increases the risk of renal failure and causes a high global disease burden.
Hui Zhao   +7 more
doaj   +1 more source

Chromatographic separation and identification of some peptides in partial hydroylsates of gelatin [PDF]

open access: yes, 1953
Recently we have been engaged in a study of the chemical structure of collagen and gelatin with the object of determining the sequence of the amino acid residues in the polypeptide chains of these proteins.
Green, F. Charlotte   +2 more
core  

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