Results 81 to 90 of about 2,785,119 (387)

Antimicrobial Peptides

Pharmaceuticals, 2013
The rapid increase in drug-resistant infections has presented a serious challenge to antimicrobial therapies. The failure of the most potent antibiotics to kill “superbugs” emphasizes the urgent need to develop other control agents.
A. Bahar, D. Ren
semanticscholar   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Lipid Vesicles Loaded with an HIV-1 Fusion Inhibitor Peptide as a Potential Microbicide

Pharmaceutics, 2020
The effective use of fusion inhibitor peptides against cervical and colorectal infections requires the development of sustained release formulations.
Elena Sánchez-López, Anna Paús, Ignacio Pérez-Pomeda, Ana Calpena, Isabel Haro, María José Gómara   +5 more
doaj   +1 more source

Coarse-grained simulation of transmembrane peptides in the gel phase [PDF]

, 2013
We use Dissipative Particle Dynamics simulations, combined with parallel tempering and umbrella sampling, to investigate the potential of mean force between model transmembrane peptides in the various phases of a lipid bilayer, including the low ...
Allen, Armstrong, Ash, Berkowitz, de Kruijff, de Meyer, de Meyer, Earl, Espanol, Gennis, Groot, Gumbart, Ibrahim H. Al-Lehyani, Israelachvili, Jakobsen, Jakobsen, John M.A. Grime, Kim McKelvey, Kranenburg, Leach, Lindahl, Lodish, Matthew Bano, Michael P. Allen, Morein, Neder, Park, Psachoulia, Rodgers, Roux, Shinoda, Sparr, Strandberg, Sugita, van der Ploeg, Venturoli, Venturoli, West, Yiannourakou   +38 more
core   +1 more source

Bioactive Peptides

Foods, 2017
The increased consumer awareness of the health promoting effects of functional foods and nutraceuticals is the driving force of the functional food and nutraceutical market.
E. Daliri, D. Oh, Byong-hee Lee
semanticscholar   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Mol. Cell. Proteomics [PDF]

, 2012
Chemical cross-linking in combination with mass spectrometric analysis offers the potential to obtain low-resolution structural information from proteins and protein complexes. Identification of peptides connected by a cross-link provides direct evidence
Aebersold, R., Bohn, S., Förster, F., Herzog, F., Leitner, A., Reischl, R., Walzthoeni, T.   +6 more
core   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Self-assembly antimicrobial peptide for treatment of multidrug-resistant bacterial infection

Journal of Nanobiotechnology
The wide-spreading of multidrug resistance poses a significant threat to human and animal health. Although antimicrobial peptides (AMPs) show great potential application, their instability has severely limited their clinical application.
Xuanxuan Ma, Na Yang, Ruoyu Mao, Ya Hao, Yuanyuan Li, Ying Guo, Da Teng, Yinhua Huang, Jianhua Wang   +8 more
doaj   +1 more source

The roles of gut microbiota and its metabolites in diabetic nephropathy

Frontiers in Microbiology, 2023
Diabetic nephropathy (DN) is a severe microvascular complication of diabetes, which increases the risk of renal failure and causes a high global disease burden.
Hui Zhao, Hui Zhao, Cheng-E Yang, Tian Liu, Ming-Xia Zhang, Yan Niu, Ming Wang, Jun Yu   +7 more
doaj   +1 more source