Results 151 to 160 of about 147,833 (381)
Advanced Science, EarlyView.These study underscores the pivotal role of neutrophil‐derived myeloid‐related protein 14 (MRP14) in the pathophysiology of acute ischemic stroke (AIS). MRP14 not only disrupts mitochondrial function, thereby inhibiting microglial phagocytosis of neutrophils, but also activates microglial pyroptosis, exacerbating neuroinflammation following AIS ...
Huijuan Jin +10 more
wiley +1 more source
Zymogram Assay for the Detection of Peptidoglycan Hydrolases in Streptococcus mutans
Bio-Protocol, 2013 Peptidoglycan hydrolases or autolysins are enzymes capable of cleaving covalent bonds in bacterial peptidoglycan cell wall layer. They can participate in the cell division process, in the release of turnover products from peptidoglycan during cell growth,
Delphine Dufour, Céline Lévesque
doaj +1 more source
Antibiotics, 2019 The peptidoglycan sacculus of both Gram-positive and Gram-negative bacteria acts as a protective mesh and provides structural support around the entirety of the cell.
Ashley S. Brott, A. Clarke
semanticscholar +1 more source
Advanced Science, EarlyView.The research team integrated a potentiometrically controlled pH electrode with carbon nanotube (CNT) field‐effect transistor (FET) biosensors on a single chip using compatible processes. By employing zonal modification and optimized pH‐sensitive probes, they achieved simultaneous quadruple‐target detection and tenfold reusability under physiological ...
Bo Xiao +6 more
wiley +1 more source
Reduced peptidoglycan synthesis capacity impairs growth of E. coli at high salt concentration
mBioGram-negative bacteria have a thin peptidoglycan layer between the cytoplasmic and outer membranes protecting the cell from osmotic challenges. Hydrolases of this structure are needed to cleave bonds to allow the newly synthesized peptidoglycan strands ...
Dema Alodaini +11 more
doaj +1 more source
Activity Assays for Bacteriophage Endolysin PlyPy
Bio-Protocol, 2014 Bacterial viruses (bacteriophages) escape and kill their host by degrading the bacterial peptidoglycan layer through the mechanism of enzymes called endolysins: peptidoglycan degrading enzymes.
Rolf Lood, Vincent Fischetti
doaj +1 more source
The penicillin-binding proteins: structure and role in peptidoglycan biosynthesis.
FEMS Microbiology Reviews, 2008 Penicillin-binding proteins (PBPs) have been scrutinized for over 40 years. Recent structural information on PBPs together with the ongoing long-term biochemical experimental investigations, and results from more recent techniques such as protein ...
E. Sauvage +4 more
semanticscholar +1 more source
The peptidoglycan recognition proteins (PGRPs).
Genome biology, 2006 Peptidoglycan recognition proteins (PGRPs) are innate immunity molecules present in insects, mollusks, echinoderms, and vertebrates, but not in nematodes or plants. PGRPs have at least one carboxy-terminal PGRP domain (approximately 165 amino acids long), which is homologous to bacteriophage and bacterial type 2 amidases.
Roman Dziarski, Dipika Gupta
openaire +3 more sources
Advanced Science, EarlyView.A tailored bio‐targeted catalytic strategy based on a bacteria‐specific artificial biocatalyst (MoS2/Fe@mercaptophenylboronic acid@hyaluronic acid, MFBH) is proposed for treating bacterial endophthalmitis. This strategy exhibits high‐efficiency peptidoglycan‐targeted bactericidal efficacy in vivo following a single intravitreal injection of an ...
Caixia Sun +9 more
wiley +1 more source
Advanced Science, EarlyView.Bacterial cell walls (CWs) extracted from Porphyromonas gingivalis are nanofabricated to form the CW vesicles (CWV), which have intrinsic peroxidase‐mimicking and sonodynamic activities due to the presence of µ‐oxo bisheme and meanwhile retain a large amount of lipopolysaccharide.
Meng Yang +9 more
wiley +1 more source