Results 11 to 20 of about 121,463 (292)
mBio, 2021 Gram-negative bacteria resist external stresses due to cell envelope rigidity, which is provided by two membranes and a peptidoglycan layer. The outer membrane (OM) surface contains lipopolysaccharide (LPS; contains O-antigen) or lipooligosaccharide (LOS)
Brent W. Simpson +5 more
doaj +2 more sources
Peptidoglycan precursor synthesis along the sidewall of pole-growing mycobacteria
eLife, 2018 Rod-shaped mycobacteria expand from their poles, yet d-amino acid probes label cell wall peptidoglycan in this genus at both the poles and sidewall. We sought to clarify the metabolic fates of these probes.
Alam García-Heredia +10 more
doaj +2 more sources
Enterococcus peptidoglycan remodeling promotes checkpoint inhibitor cancer immunotherapy
Science, 2021 SagA promotes immunotherapy response The gut microbiome can influence the treatment outcome for cancer patients receiving PD-L1 immunotherapy, but the mechanisms underlying favorable responses are unclear. Griffin et al.
Matthew E. Griffin +7 more
openalex +3 more sources
Peptidoglycan synthesis drives an FtsZ-treadmilling-independent step of cytokinesis
Nature, 2018 Peptidoglycan is the main component of the bacterial wall and protects cells from the mechanical stress that results from high intracellular turgor.
João M. Monteiro +12 more
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Masters of Misdirection: Peptidoglycan Glycosidases in Bacterial Growth
Journal of Bacteriology, 2023 The dynamic composition of the peptidoglycan cell wall has been the subject of intense research for decades, yet how bacteria coordinate the synthesis of new peptidoglycan with the turnover and remodeling of existing peptidoglycan remains elusive ...
Anna I. Weaver, A. Taguchi, Tobias Dörr
semanticscholar +1 more source
Journal of Extracellular Vesicles, 2021 Gram‐positive bacteria ubiquitously produce membrane vesicles (MVs), and although they contribute to biological functions, our knowledge regarding their composition and immunogenicity remains limited.
Natalie J. Bitto +9 more
semanticscholar +1 more source
Growth and Division of the Peptidoglycan Matrix.
Annual Review of Microbiology, 2021 Most bacteria are surrounded by a peptidoglycan cell wall that defines their shape and protects them from osmotic lysis. The expansion and division of this structure therefore plays an integral role in bacterial growth and division.
Patricia D A Rohs, T. Bernhardt
semanticscholar +1 more source
FEMS Microbiology Reviews, 2022 Staphylococcus aureus is an important human and livestock pathogen that is well-protected against environmental insults by a thick cell wall. Accordingly, the wall is a major target of present-day antimicrobial therapy. Unfortunately, S.
Min Wang, G. Buist, J. V. van Dijl
semanticscholar +1 more source
Peptidoglycan maturation controls outer membrane protein assembly
Nature, 2022 Linkages between the outer membrane of Gram-negative bacteria and the peptidoglycan layer are crucial for the maintenance of cellular integrity and enable survival in challenging environments1–5.
Gideon Mamou +10 more
semanticscholar +1 more source
Peptidoglycan: Structure, Synthesis, and Regulation.
EcoSal Plus, 2021 Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much interest for its biology, its potential for the discovery of novel ...
Shambhavi Garde +2 more
semanticscholar +1 more source