Results 21 to 30 of about 147,833 (381)
Journal of Extracellular Vesicles, 2021 Gram‐positive bacteria ubiquitously produce membrane vesicles (MVs), and although they contribute to biological functions, our knowledge regarding their composition and immunogenicity remains limited.
Natalie J. Bitto +9 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 The synthesis of a peptidoglycan septum is a fundamental part of bacterial fission and is driven by a multiprotein dynamic complex called the divisome.
Mohamed Attaibi, T. den Blaauwen
semanticscholar +1 more source
Nature Communications, 2021 The commensal fungus Candida albicans often causes life-threatening infections in patients who are immunocompromised with high mortality. A prominent but poorly understood risk factor for the C.
Chew Teng Tan +3 more
semanticscholar +1 more source
Structural basis for peptidoglycan binding by peptidoglycan recognition proteins [PDF]
Proceedings of the National Academy of Sciences, 2004 Peptidoglycan (PGN) recognition proteins (PGRPs) are pattern-recognition receptors of the innate immune system that bind and, in some cases, hydrolyze bacterial PGNs. We determined the crystal structure, at 2.30-Å resolution, of the C-terminal PGN-binding domain of human PGRP-Iα in complex with a muramyl tripeptide representing the core of
Rongjin Guan +5 more
openaire +3 more sources
The Absence of a Mature Cell Wall Sacculus in Stable Listeria monocytogenes L-Form Cells Is Independent of Peptidoglycan Synthesis. [PDF]
PLoS ONE, 2016 L-forms are cell wall-deficient variants of otherwise walled bacteria that maintain the ability to survive and proliferate in absence of the surrounding peptidoglycan sacculus.
Patrick Studer +7 more
doaj +1 more source
Specificity determinants for lysine incorporation in staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex [PDF]
, 2013 Background: MurE controls stereo chemical incorporation of Lysine or diaminopimelate into peptidoglycan stem peptides Results: The structure of S.aureus MurE reveals an unexpected lack of specificity for Lysine within the active site.
Barreteau +72 more
core +2 more sources
A SpoIID Homolog Cleaves Glycan Strands at the Chlamydial Division Septum
mBio, 2019 Chlamydiales species are obligate intracellular bacteria lacking a classical peptidoglycan sacculus but relying on peptidoglycan synthesis for cytokinesis.
Nicolas Jacquier +5 more
doaj +1 more source
Innate Immunity, 2020 Defensins are critical components of the innate immune system and play an important role in the integration of innate and adaptive immune responses.
Juan Huang +6 more
doaj +1 more source
Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection*
Journal of Biological Chemistry, 2003 Nod2 activates the NF-κB pathway following intracellular stimulation by bacterial products. Recently, mutations inNod2 have been shown to be associated with Crohn's disease, suggesting a role for bacteria-host interactions in the etiology of this ...
S. Girardin +7 more
semanticscholar +1 more source
Frontiers in Microbiology, 2018 Peptidoglycan is the fundamental structural constituent of the bacterial cell wall. Despite many years of research, the architecture of peptidoglycan is still largely elusive.
Kang Li +12 more
doaj +1 more source