Results 31 to 40 of about 118,125 (294)
A peptidoglycan hydrolase motif within the mycobacteriophage TM4 tape measure protein promotes efficient infection of stationary phase cells [PDF]
, 2006 The predominant morphotype of mycobacteriophage virions has a DNA-containing capsid attached to a long flexible non-contractile tail, features characteristic of the Siphoviridae.
Hatfull, GF, Piuri, M
core +3 more sources
Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs) [PDF]
Proceedings of the National Academy of Sciences, 2006 The innate immune system constitutes the first line of defense against microorganisms in both vertebrates and invertebrates. Although much progress has been made toward identifying key receptors and understanding their role in host defense, far less is known about how these receptors recognize microbial ligands. Such studies have been severely hampered
Swaminathan, Chittoor P. +8 more
openaire +4 more sources
Peptidoglycan and Nod Receptor [PDF]
, 2014 Bacterial cells are encompassed by a macromolecular network of peptidoglycan, the major component of bacterial cell walls that provides the cell wall strength and determines bacterial morphology. Eukaryotic organisms sense the presence of bacteria by detecting peptidoglycan fragments shed by the bacterium or released through hydrolytic attack by host ...
Catherine Werts +7 more
openaire +3 more sources
Resistance to mucosal lysozyme compensates for the fitness deficit of peptidoglycan modifications by Streptococcus pneumoniae. [PDF]
PLoS Pathogens, 2008 The abundance of lysozyme on mucosal surfaces suggests that successful colonizers must be able to evade its antimicrobial effects. Lysozyme has a muramidase activity that hydrolyzes bacterial peptidoglycan and a non-muramidase activity attributable to ...
Kimberly M Davis +3 more
doaj +1 more source
Circumferential gap propagation in an anisotropic elastic bacterial sacculus [PDF]
Phys. Rev. E 89, 012704 (2014), 2013 We have modelled stress concentration around small gaps in anisotropic elastic sheets, corresponding to the peptidoglycan sacculus of bacterial cells, under loading corresponding to the effects of turgor pressure in rod-shaped bacteria. We find that under normal conditions the stress concentration is insufficient to mechanically rupture bacteria, even ...
arxiv +1 more source
Functional characterization of a short peptidoglycan recognition protein from Chinese giant salamander (Andrias davidianus) [PDF]
, 2017 This work was supported by the National Natural Science Foundation of China (Grant no. 31302221, 31172408 and 31272666) and Jiangsu Province (Grant no.
Chang, Mingxian +8 more
core +1 more source
Peptidoglycan Composition in Neisseria [PDF]
, 2019 The composition of Neisseria peptidoglycan has been of scientific interest for over four decades. Initial investigations focused on discovering the mechanisms causing rising rates of antibiotic resistance in N. gonorrhoeae by determining differences in peptidoglycan composition in penicillin susceptible and resistant strains.
Ryan E. Schaub, Joseph P. Dillard
openaire +3 more sources
Imbalance of peptidoglycan biosynthesis alters the cell surface charge of Listeria monocytogenes
The Cell Surface, 2022 The bacterial cell wall is composed of a thick layer of peptidoglycan and cell wall polymers, which are either embedded in the membrane or linked to the peptidoglycan backbone and referred to as lipoteichoic acid (LTA) and wall teichoic acid (WTA ...
Lisa Maria Schulz +4 more
doaj
Covalent attachment of proteins to peptidoglycan [PDF]
FEMS Microbiology Reviews, 2008 Bacterial surface proteins are key players in host-symbiont or host-pathogen interactions. How these proteins are targeted and displayed at the cell surface are challenging issues of both fundamental and clinical relevance. While surface proteins of Gram-negative bacteria are assembled in the outer membrane, Gram-positive bacteria predominantly utilize
Michel Arthur +9 more
openaire +4 more sources
PLoS ONE, 2021 Daptomycin is a cyclic lipopeptide antibiotic used in the clinic for treatment of severe enterococcal infections. Recent reports indicate that daptomycin targets active cellular processes, specifically, peptidoglycan biosynthesis. Within, we examined the
Rachel D Johnston +4 more
doaj +1 more source