Results 111 to 120 of about 20,249 (205)
This graphical abstract summarizes the current advances in dietary exosome‐like nanoparticles (ELNs), highlighting their biogenesis pathways (MVB‐dependent, vacuole‐mediated, and EXPO routes), molecular composition (nucleic acids, lipids, proteins, and bioactive compounds), and major preparation strategies including differential ultracentrifugation ...
Nidesha Randeni +3 more
wiley +1 more source
Phage-derived peptidoglycan degrading enzymes: challenges and future prospects for in vivo therapy [PDF]
Peptidoglycan degrading enzymes are of increasing interest as antibacterial agents, especially against multi-drug resistant pathogens. Herein we present a review about the biological features of virion-associated lysins and endolysins, phage-derived ...
Azeredo, Joana +2 more
core +2 more sources
Dysbiosis in the Pathogenesis of Atopic Dermatitis
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by epidermal barrier dysfunction and immune dysregulation. Recent research highlights cutaneous dysbiosis as a critical factor in its pathogenesis. In this review, we summarize the interplay between the skin microbiota and host immunity, contrasting the homeostatic ...
Hiroki Okamoto, Yuumi Nakamura
wiley +1 more source
Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles’ heel for the TB-causing pathogen [PDF]
Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis, remains one of the leading causes of mortality across the world. There is an urgent requirement to build a robust arsenal of effective antimicrobials, targeting novel ...
Bhakta, S +6 more
core +2 more sources
Peptidoglycan hydrolases are promising alternatives for combating pathogens due to their specificity and potent bacteriolytic activity. In this study, a novel M23 peptidase from Streptococcus thermophilus NCTC10353, designated StM23, was discovered and ...
Magdalena Kaus-Drobek +8 more
doaj +1 more source
Reduced Binding of the Endolysin LysTP712 to Lactococcus lactis ΔftsH Contributes to Phage Resistance [PDF]
Absence of the membrane protease FtsH in Lactococcus lactis hinders release of the bacteriophage TP712. In this work we have analyzed the mechanism responsible for the non-lytic phenotype of L. lactis ΔftsH after phage infection.
Campelo, Ana B. +6 more
core +2 more sources
Comprehensive analysis of peptidoglycan hydrolases in Caulobacter crescentus
The peptidoglycan (PG) sacculus is a large macromolecule enclosing most bacterial cells. During progression of the cell cycle, it needs to be continuously remodelled to enable elongation of the cell body and, finally, cell division.
Zielinska, Aleksandra +1 more
openaire +3 more sources
Reduced peptidoglycan synthesis capacity impairs growth of E. coli at high salt concentration
Gram-negative bacteria have a thin peptidoglycan layer between the cytoplasmic and outer membranes protecting the cell from osmotic challenges. Hydrolases of this structure are needed to cleave bonds to allow the newly synthesized peptidoglycan strands ...
Dema Alodaini +11 more
doaj +1 more source
The Composition of the Cell Envelope Affects Conjugation in Bacillus subtilis [PDF]
Conjugation in bacteria is the contact-dependent transfer of DNA from one cell to another via donor-encoded conjugation machinery. It is a major type of horizontal gene transfer between bacteria.
Grossman, Alan Davis +1 more
core +1 more source
Phenotypic and genotypic characterization of peptidoglycan hydrolases of Lactobacillus sakei
Lactobacillus sakei, a lactic acid bacterium naturally found in fresh meat and sea products, is considered to be one of the most important bacterial species involved in meat fermentation and bio-preservation. Several enzymes of Lb. sakei species contributing to microbial safeguarding and organoleptic properties of fermented-meat were studied.
Najjari, Afef +6 more
openaire +7 more sources

