Results 111 to 120 of about 12,407 (196)

Nucleotide Sequence of Conjugative Prophage Φ1207.3 (formerly Tn1207.3) carrying the mef(A)/msr(D) genes for efflux resistance to macrolides in Streptococcus pyogenes

Frontiers in Microbiology, 2014
Genetic element Φ1207.3 (formerly Tn1207.3) is a prophage of Streptococcus pyogenes which carries the macrolide efflux resistance genes mef(A)/msr(D) and is capable of conjugal transfer among streptococci. Complete nucleotide sequence showed that Φ1207.3
Francesco eIannelli, Maria eSantagati, Francesco eSantoro, Marco R Oggioni, Stefania eStefani, Gianni ePozzi   +5 more
doaj   +1 more source

SpyB, a small heme-binding protein, affects the composition of the cell wall in Streptococcus pyogenes

Frontiers in Cellular and Infection Microbiology, 2016
Streptococcus pyogenes (Group A Streptococcus or GAS) is a haemolytic human pathogen associated with a wide variety of infections ranging from minor skin and throat infections to life-threatening invasive diseases.
Rebecca J Edgar, Jing Chen, Sashi Kant, Elena Rechkina, Jeffrey S Rush, Lennart Scott Forsberg, Bernhard Jaehrig, Parastoo Azadi, Veronika Tchesnokova, Evgeni V Sokurenko, Haining Zhu, Konstantin V Korotkov, Vijay Pancholi, Natalia Korotkova   +13 more
doaj   +1 more source

Thioester analogues of peptidoglycan fragment MurNAc-L-Ala-gamma-D-Glu as substrates for peptidoglycan hydrolase MurNAc-L-Ala amidase

, 2002
MurNAc-L-amidase is one of a family of peptidoglycan hydrolases which catalyses the breakdown of bacterial peptidoglycan. Analogues of the peptidoglycan fragment MurNAc-L-Ala-gamma-D-Glu containing S-thiolactic acid in place of L-alanine were synthesised
Harding, R. L., Bugg, T. D. H., Henshaw, J., Tilling, J.   +3 more
core   +1 more source

Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis.

PLoS Pathogens, 2017
Enterococcus faecalis is an opportunistic pathogen frequently isolated in clinical settings. This organism is intrinsically resistant to several clinically relevant antibiotics and can transfer resistance to other pathogens. Although E.
Bartłomiej Salamaga, Tomasz K Prajsnar, Ana Jareño-Martinez, Joost Willemse, Martin A Bewley, Françoise Chau, Tassadit Ben Belkacem, Annemarie H Meijer, David H Dockrell, Stephen A Renshaw, Stéphane Mesnage   +10 more
doaj   +1 more source

Enhanced staphylolytic activity of the staphylococcus aureus bacteriophage VB_saus-philpla88 virion-associated peptidoglycan hydrolase HYDH5: fusions, deletions and synergy with LYSH5

, 2011
Virion-associated peptidoglycan-hydrolases are potential antimicrobials due to their ability to lyse Gram-positive bacteria on contact. Full-length HydH5, a virion- associated peptidoglycan-hydrolase from the Staphylococcus aureus bacteriophage vB_SauS ...
Rodríguez, Lorena, Donovan, David M., Martínez Fernández, Beatriz, Rodríguez González, Ana, García Suárez, María Pilar   +4 more
core  

Purification and Characterization of Cell Wall Hydrolase from Alkalophilic Bacillus mutanolyticus YU5215 [PDF]

, 2004
Streptococcus mutans has the capacity of inducing dental caries. Thus, to develop a novel way of preventing dental caries, a cell wall hydrolase-producing strain was isolated and its characteristics were investigated.
유윤정
core  

A Proteolytic Complex Targets Multiple Cell Wall Hydrolases in Pseudomonas aeruginosa

mBio, 2018
Carboxy-terminal processing proteases (CTPs) occur in all three domains of life. In bacteria, some of them have been associated with virulence. However, the precise roles of bacterial CTPs are poorly understood, and few direct proteolytic substrates have
Disha Srivastava, Jin Seo, Binayak Rimal, Sung Joon Kim, Stephanie Zhen, Andrew J. Darwin   +5 more
doaj   +1 more source

Lytic activity of the virion-associated peptidoglycan hydrolase HydH5 of Staphylococcus aureus bacteriophage vB_SauS-phiIPLA88 [PDF]

, 2011
Background Staphylococcus aureus is a food-borne pathogen and the most common cause of infections in hospitalized patients. The increase in the resistance of this pathogen to antibacterials has made necessary the development of new anti-staphylococcal ...
Rodríguez, Lorena, Zhou Yuan, Beatriz Martínez, Martínez Beatriz, Pilar García, Ana Rodríguez, Donovan, David M., Zhou, Yuan, Rodríguez Ana, Rodríguez González, Ana, García Suárez, María Pilar, Donovan David M, Yuan Zhou, García Pilar, Martínez Fernández, Beatriz, Lorena Rodríguez, Rodríguez Lorena, David M Donovan   +17 more
core   +1 more source

Functional profiling of CHAP domain-containing peptidoglycan hydrolases of Staphylococcus aureus USA300 uncovers potential targets for anti-staphylococcal therapies

International Journal of Medical Microbiology
The bacterial pathogen Staphylococcus aureus employs a thick cell wall for protection against physical and chemical insults. This wall requires continuous maintenance to ensure strength and barrier integrity, but also to permit bacterial growth and ...
Min Wang, Xiaofang Li, Francis M. Cavallo, Harita Yedavally, Sjouke Piersma, Elisa J.M. Raineri, Elias Vera Murguia, Jeroen Kuipers, Zhenhua Zhang, Jan Maarten van Dijl, Girbe Buist   +10 more
doaj   +1 more source

Enhancing stability and safety of chimeric peptidoglycan hydrolases by linker engineering

Applied Microbiology and Biotechnology
Abstract Spread of antimicrobial resistance and lack of new antibiotics have brought attention to alternative strategies of combating pathogenic bacteria. One of these strategies takes advantage of the bacteriolytic activity of peptidoglycan hydrolases.
Mitkowski, Paweł, Jagielska, Elżbieta, Korzeniowska nee Wiweger, Małgorzata, Nowacka, Marzena, Kjos, Morten, Kranjec, Christian, Sabała, Izabela   +6 more
openaire   +3 more sources