Results 101 to 110 of about 12,407 (196)

Probiotics Cancer Interaction, Prevention, and Therapy

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Cancer is a significant global health concern and ranks as the second most common cause of death on a worldwide scale. A combination of hereditary and lifestyle variables, such as diet, smoking, alcohol consumption, physical exercise, and the gut microbiota, impacts cancer development. Dysbiosis, an imbalance in gut microorganisms, can promote
Mostafa Saebi, Amir Hossein Barjasteh, Mahmoud Mahmoudi, Ramiar Kamal Kheder, Setayesh Ramazanpour, Negar Ebadpour, Afsane Fadaee, Seyed‐Alireza Esmaeili   +7 more
wiley   +1 more source

Phage–derived Endolysins as Potential Antibacterials : A Study of Peptidoglycan Hydrolase and Mycolylarabinogalactan Esterase Enzymes [PDF]

, 2019
Bacteriophages, or phages, are viruses that infect bacteria, at the end of their life cycle produce a set of enzymes called endolysins to lyse host cells from within, facilitating the release of the viral progeny.
Abouhmad, Adel
core  

Bacterial glycobiology: rhamnose-containing cell wall polysaccharides in Gram-positive bacteria.

, 2016
The composition of the Gram-positive cell wall is typically described as containing peptidoglycan, proteins and essential secondary cell wall structures called teichoic acids, which comprise approximately half of the cell wall mass.
Sutcliffe, Iain, van Sorge, Nina, Mistou, Michel-Yves   +2 more
core   +1 more source

Various checkpoints prevent the synthesis of Staphylococcus aureus peptidoglycan hydrolase LytM in the stationary growth phase

, 2016
In Staphylococcus aureus, peptidoglycan metabolism plays a role in the host inflammatory response and pathogenesis. Transcription of the peptidoglycan hydrolases is activated by the essential 2-component system WalKR at low cell density.
Brian C. Jester (2157559), Isabelle Caldelari (64721), Sandrine Boisset (153256), Thomas Geissmann (25003), François Vandenesch (112293), Pascale Romby (155460), Efthimia Lioliou (155444), Pierre Fechter (155453), Anne-Catherine Helfer (155449), Sarah Dubrac (145194)   +9 more
core   +1 more source

Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence [PDF]

Streptococcus pneumoniae is a major cause of life-threatening diseases worldwide. Here we provide an in-depth functional characterization of LytB, the peptidoglycan hydrolase responsible for physical separation of daughter cells.
Iglesias-Bexiga M, Gray J, Diez-Martinez R, Vollmer W, Menendez M, Rico-Lastres P, Mobashery S, Lee M, Bustamante N, Aldridge C, Hesek D, Garcia P   +11 more
core  

Genetic dissection of the type VI secretion system in Acinetobacter and identification of a novel peptidoglycan hydrolase, TagX, required for its biogenesis [PDF]

, 2016
UNLABELLED: The type VI secretion system (T6SS) is a widespread secretory apparatus produced by Gram-negative bacteria that has emerged as a potent mediator of antibacterial activity during interbacterial interactions.
Wright, MS, Adams, MD, Hennon, SW, Foster, LJ, Feldman, MF, Ayala, JA, Weber, BS, Scott, NE, de Berardinis, V   +8 more
core   +1 more source

From discovery to potential application: engineering a novel M23 peptidase to combat Listeria monocytogenes

Scientific Reports
Peptidoglycan hydrolases are promising alternatives for combating pathogens due to their specificity and potent bacteriolytic activity. In this study, a novel M23 peptidase from Streptococcus thermophilus NCTC10353, designated StM23, was discovered and ...
Magdalena Kaus-Drobek, Marzena Nowacka, Magdalena Gewartowska, Małgorzata Korzeniowska nee Wiweger, Merete Rusås Jensen, Trond Møretrø, Even Heir, Elżbieta Nowak, Izabela Sabała   +8 more
doaj   +1 more source

Reduced peptidoglycan synthesis capacity impairs growth of E. coli at high salt concentration

mBio
Gram-negative bacteria have a thin peptidoglycan layer between the cytoplasmic and outer membranes protecting the cell from osmotic challenges. Hydrolases of this structure are needed to cleave bonds to allow the newly synthesized peptidoglycan strands ...
Dema Alodaini, Victor Hernandez-Rocamora, Gabriela Boelter, Xuyu Ma, Micheal B. Alao, Hannah M. Doherty, Jack A. Bryant, Patrick Moynihan, Danesh Moradigaravand, Monika Glinkowska, Waldemar Vollmer, Manuel Banzhaf   +11 more
doaj   +1 more source

Comparative flux control through the cytoplasmic phase of cell wall biosynthesis [PDF]

The introduction of antibacterial drugs in the middle of the last century heralded a new era in the treatment of infectious disease. However the parallel emergence of antibiotic resistance and decline in new drug discovery threatens these advances. The
Bearup, Daniel James
core  

Potential of the Virion-Associated Peptidoglycan Hydrolase HydH5 and Its Derivative Fusion Proteins in Milk Biopreservation

, 2013
Bacteriophage lytic enzymes have recently attracted considerable interest as novel antimicrobials against Gram-positive bacteria. In this work, antimicrobial activity in milk of HydH5 [a virion-associated peptidoglycan hydrolase (VAPGH) encoded by the ...
Lorena Rodríguez-Rubio, Rodríguez, Lorena, Beatriz Martínez, Pilar García, Ana Rodríguez, Donovan, David M., Martínez Fernández, Beatriz, David M Donovan, García Suárez, María Pilar, Rodríguez González, Ana   +9 more
core   +1 more source