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Two New M23 Peptidoglycan Hydrolases With Distinct Net Charge [PDF]

open access: goldFrontiers in Microbiology, 2021
Bacterial peptidoglycan hydrolases play an essential role in cell wall metabolism during bacterial growth, division, and elongation (autolysins) or in the elimination of closely related species from the same ecological niche (bacteriocins).
Alicja Wysocka   +3 more
doaj   +6 more sources

Peptidoglycan Hydrolases of Local Lactic Acid Bacteria from Kazakh Traditional Food [PDF]

open access: diamondCentral Asian Journal of Global Health, 2014
Introduction: Peptidoglycan (PG) is a major component of the cell wall of Gram-positive bacteria and is essential for maintaining the integrity of the bacterial cell and its shape.
Serik Shaikhin   +6 more
doaj   +7 more sources

Identification of key peptidoglycan hydrolases for morphogenesis, autolysis, and peptidoglycan composition of Lactobacillus plantarum WCFS1 [PDF]

open access: goldMicrobial Cell Factories, 2012
Background Lactobacillus plantarum is commonly used in industrial fermentation processes. Selected strains are also marketed as probiotics for their health beneficial effects.
Rolain Thomas   +6 more
doaj   +10 more sources

One fold, many functions—M23 family of peptidoglycan hydrolases [PDF]

open access: yesFrontiers in Microbiology, 2022
Bacterial cell walls are the guards of cell integrity. They are composed of peptidoglycan that provides rigidity to sustain internal turgor and ensures isolation from the external environment.
Alicja Razew   +4 more
doaj   +4 more sources

Bacterial Cell Enlargement Requires Control of Cell Wall Stiffness Mediated by Peptidoglycan Hydrolases [PDF]

open access: goldmBio, 2015
Most bacterial cells are enclosed in a single macromolecule of the cell wall polymer, peptidoglycan, which is required for shape determination and maintenance of viability, while peptidoglycan biosynthesis is an important antibiotic target.
Richard Wheeler   +9 more
doaj   +3 more sources

Phenotypic and genotypic characterization of peptidoglycan hydrolases of Lactobacillus sakei [PDF]

open access: yesJournal of Advanced Research, 2016
Lactobacillus sakei, a lactic acid bacterium naturally found in fresh meat and sea products, is considered to be one of the most important bacterial species involved in meat fermentation and bio-preservation. Several enzymes of Lb.
Afef Najjari   +6 more
doaj   +8 more sources

Dimer-monomer transition defines a hyper-thermostable peptidoglycan hydrolase mined from bacterial proteome by lysin-derived antimicrobial peptide-primed screening [PDF]

open access: goldeLife
Phage-derived peptidoglycan hydrolases (i.e. lysins) are considered promising alternatives to conventional antibiotics due to their direct peptidoglycan degradation activity and low risk of resistance development.
Li Zhang   +11 more
doaj   +3 more sources

Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM [PDF]

open access: yeseLife
Orchestrated action of peptidoglycan (PG) synthetases and hydrolases is vital for bacterial growth and viability. Although the function of several PG synthetases and hydrolases is well understood, the function, regulation, and mechanism of action of PG ...
Lina Antenucci   +6 more
doaj   +2 more sources

The Protozoan Trichomonas vaginalis Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases [PDF]

open access: yesmBio, 2018
The human eukaryotic pathogen Trichomonas vaginalis causes trichomoniasis, a prevalent sexually transmitted infection. This extracellular protozoan is intimately associated with the human vaginal mucosa and microbiota, but key aspects of the complex ...
Jully Pinheiro   +8 more
doaj   +2 more sources

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