Results 131 to 140 of about 14,172 (195)

Antibacterial and anti-biofilm activity of diarylureas against Enterococcus faecium by suppressing the gene expression of peptidoglycan hydrolases and adherence. [PDF]

Front Microbiol, 2022
Xie Y, Wang L, Yang Y, Zha L, Zhang J, Rong K, Tang W, Zhang J.   +7 more
europepmc   +1 more source

From discovery to potential application: engineering a novel M23 peptidase to combat Listeria monocytogenes

Scientific Reports
Peptidoglycan hydrolases are promising alternatives for combating pathogens due to their specificity and potent bacteriolytic activity. In this study, a novel M23 peptidase from Streptococcus thermophilus NCTC10353, designated StM23, was discovered and ...
Magdalena Kaus-Drobek, Marzena Nowacka, Magdalena Gewartowska, Małgorzata Korzeniowska nee Wiweger, Merete Rusås Jensen, Trond Møretrø, Even Heir, Elżbieta Nowak, Izabela Sabała   +8 more
doaj   +1 more source

Electrostatic Interaction with the Bacterial Cell Envelope Tunes the Lytic Activity of Two Novel Peptidoglycan Hydrolases. [PDF]

Microbiol Spectr, 2022
Wysocka A, Łężniak Ł, Jagielska E, Sabała I.   +3 more
europepmc   +1 more source

Magnesium rescues the morphology of Bacillus subtilis mreB mutants through its inhibitory effect on peptidoglycan hydrolases. [PDF]

Sci Rep, 2022
Tesson B, Dajkovic A, Keary R, Marlière C, Dupont-Gillain CC, Carballido-López R.   +5 more
europepmc   +1 more source

Chapter 12. Measure of peptidoglycan hydrolase activity Running head: peptidoglycan remodelling enzymes

, 2017
Most of the gene clusters encoding multiprotein complexes of the bacterial cell envelope, such as conjugation and secretion systems, Type IV pili and flagella, bear a gene encoding an enzyme with peptidoglycan hydrolase activity. These enzymes are usually glycoside hydrolases that cleave the glycan chains of the peptidoglycan.
Cascales, E., Santin, Yoann
openaire   +1 more source

Differential binding of human and murine IgGs to catalytic and cell wall binding domains of Staphylococcus aureus peptidoglycan hydrolases. [PDF]

Sci Rep, 2021
Wang M, van den Berg S, Mora Hernández Y, Visser AH, Vera Murguia E, Koedijk DGAM, Bellink C, Bruggen H, Bakker-Woudenberg IAJM, van Dijl JM, Buist G.   +10 more
europepmc   +1 more source

The impact of metagenomic analysis on the discovery of novel endolysins

Applied Microbiology and Biotechnology
Metagenomics has revolutionized enzyme discovery by enabling the study of genetic material directly from environmental samples, bypassing the need for microbial cultivation.
Nikolaos Georgakis, Georgios E. Premetis, Panagiota Pantiora, Christina Varotsou, Charoutioun S. Bodourian, Nikolaos E. Labrou   +5 more
doaj   +1 more source

Two new enzymes that liberate undecaprenyl-phosphate to replenish the carrier lipid pool during envelope stress

mBio
The 55-carbon isoprenoid, undecaprenyl-phosphate (UndP), is a universal carrier lipid that ferries most glycans and glycopolymers across the cytoplasmic membrane in bacteria.
Ian J. Roney, David Z. Rudner
doaj   +1 more source

EnvC Homolog Encoded by Xanthomonas citri subsp. citri Is Necessary for Cell Division and Virulence

Microorganisms
Peptidoglycan hydrolases are enzymes responsible for breaking the peptidoglycan present in the bacterial cell wall, facilitating cell growth, cell division and peptidoglycan turnover. Xanthomonas citri subsp. citri (X.
Michelle M. Pena, Thaisa Z. Martins, Doron Teper, Caio Zamuner, Helen A. Alves, Henrique Ferreira, Nian Wang, Maria Inês T. Ferro, Jesus A. Ferro   +8 more
doaj   +1 more source

Engineering of Long-Circulating Peptidoglycan Hydrolases Enables Efficient Treatment of Systemic Staphylococcus aureus Infection. [PDF]

mBio, 2020
Sobieraj AM, Huemer M, Zinsli LV, Meile S, Keller AP, Röhrig C, Eichenseher F, Shen Y, Zinkernagel AS, Loessner MJ, Schmelcher M.   +10 more
europepmc   +1 more source