Results 121 to 130 of about 9,126 (180)

Cell morphology maintenance in Bacillus subtilis through balanced peptidoglycan synthesis and hydrolysis [PDF]

, 2020
\ua9 2020, The Author(s).The peptidoglycan layer is responsible for maintaining bacterial cell shape and permitting cell division. Cell wall growth is facilitated by peptidoglycan synthases and hydrolases and is potentially modulated by components of the
Vollmer W, Sousa J, Lalk M, Daniel RA, Sassine J   +4 more
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Thioester analogues of peptidoglycan fragment MurNAc-L-Ala-gamma-D-Glu as substrates for peptidoglycan hydrolase MurNAc-L-Ala amidase

, 2002
MurNAc-L-amidase is one of a family of peptidoglycan hydrolases which catalyses the breakdown of bacterial peptidoglycan. Analogues of the peptidoglycan fragment MurNAc-L-Ala-gamma-D-Glu containing S-thiolactic acid in place of L-alanine were synthesised
Harding, R. L., Bugg, T. D. H., Henshaw, J., Tilling, J.   +3 more
core   +1 more source

CPP-Mediated Delivery of Peptidoglycan Hydrolases as Novel Enzybiotics

CPP-Mediated Delivery of Peptidoglycan Hydrolases as Novel Enzybiotics Jacob Clawson, Tina Willoughby, Daniel Morris and Jonathan McMurry Department of Biochemistry, Kennesaw State University In the medical field there has always been a topic of ...
Clawson, Jacob, Morris, Daniel, McMurry, Jonathan, Willoughby, Tina   +3 more
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Engineering of Long-Circulating Peptidoglycan Hydrolases Enables Efficient Treatment of Systemic Staphylococcus aureus Infection. [PDF]

mBio, 2020
Sobieraj AM, Huemer M, Zinsli LV, Meile S, Keller AP, Röhrig C, Eichenseher F, Shen Y, Zinkernagel AS, Loessner MJ, Schmelcher M.   +10 more
europepmc   +1 more source

The Protozoan Trichomonas vaginalis Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases [PDF]

The human eukaryotic pathogen Trichomonas vaginalis causes trichomoniasis, a prevalent sexually transmitted infection. This extracellular protozoan is intimately associated with the human vaginal mucosa and microbiota but key aspects of the complex ...
Hirt RP, Vollmer W, Simoes-Barbosa A, Black MM, Pinheiro J, Keown JR, Artuyants A, Biboy J, Goldstone DC   +8 more
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Peptidoglycan Hydrolases RipA and Ami1 Are Critical for Replication and Persistence of Mycobacterium tuberculosis in the Host. [PDF]

mBio, 2020
Healy C, Gouzy A, Ehrt S.
europepmc   +1 more source

Comparative flux control through the cytoplasmic phase of cell wall biosynthesis [PDF]

The introduction of antibacterial drugs in the middle of the last century heralded a new era in the treatment of infectious disease. However the parallel emergence of antibiotic resistance and decline in new drug discovery threatens these advances. The
Bearup, Daniel James
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A periplasmic protein modulates the proteolysis of peptidoglycan hydrolases to maintain cell wall homeostasis in <i>Escherichia coli</i>. [PDF]

Proc Natl Acad Sci U S A
Park S, Jeon WJ, Lee Y, Lim CL, Lee E, Oh HB, Lee GS, Kwon OH, Ryu B, Cho YJ, Kim CS, Yoon SI, Chung JM, Cho H.   +13 more
europepmc   +1 more source

A new peptidoglycan hydrolase in Streptococcus pneumoniae [PDF]

FEMS Microbiology Letters, 1986
openaire   +1 more source

NlpC/P60 domain-containing proteins of Mycobacterium avium subspecies paratuberculosis that differentially bind and hydrolyze peptidoglycan

, 2016
A subset of proteins containing NlpC/P60 domains are bacterial peptidoglycan hydrolases that cleave noncanonical peptide linkages and contribute to cell wall remodeling as well as cell separation during late stages of division.
McWhorter, William J., Geisbrecht, Brian V., Lingle, Cari K., Adam, Philip R., Picking, William D., Ramyar, Kasra X., Bannantine, J. P.   +6 more
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