Results 101 to 110 of about 9,126 (180)

Measure of Peptidoglycan Degradation Activity.

Most bacterial secretion systems are large machines that cross the cell envelope to deliver effectors outside the cell or directly into target cells.
Cascales, Eric, Santin, Yoann
core   +1 more source

The protozoan Trichomonas vaginalis targets bacteria with laterally-acquired NlpC/P60 peptidoglycan hydrolases

, 2020
Trichomonas vaginalisis a human eukaryotic pathogen and the causative agent of trichomoniasis, the most prevalent non-viral sexually transmitted infection worldwide.
Simoes-Barbosa, Augusto, Vollmer, Waldemar, Hirt, Robert P, Artuyants, Anastasiia, Goldstone, David C, Biboy, Jacob, Keown, Jeremy R, Pinheiro, Jully   +7 more
core   +1 more source

The role of peptidoglycan hydrolases in the formation and toxicity of Pseudomonas aeruginosa membrane vesicles. [PDF]

Microlife, 2022
Chen YC, Kalawong R, Toyofuku M, Eberl L.   +3 more
europepmc   +1 more source

Cooperativity of peptidoglycan synthases active in bacterial cell elongation.

, 2012
peer reviewedGrowth of the bacterial cell wall peptidoglycan sacculus requires the co-ordinated activities of peptidoglycan synthases, hydrolases and cell morphogenesis proteins, but the details of these interactions are largely unknown. We now show that
Breukink, Eefjan, Philippe, Jules, Banzhaf, Manuel, Vollmer, Waldemar, Breukink, E., Terrak, Mohammed, Zapun, A., Banzhaf, Manuel; id_orcid, van den Berg van Saparoea, Bart, Vollmer, W., Fraipont, C., Egan, A., Philippe, J., Zapun, Andre, Nguyen-Distèche, M., den Blaauwen, T.; id_orcid, Terrak, M., Banzhaf, M., van den Berg van Saparoea, B., Egan, Alexander, den Blaauwen, T., Fraipont, Claudine, den Blaauwen, Tanneke, Nguyen-Distèche, Martine   +23 more
core   +1 more source

NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli. [PDF]

PLoS Pathog, 2023
Barnett MJ, Pinheiro J, Keown JR, Biboy J, Gray J, Lucinescu IW, Vollmer W, Hirt RP, Simoes-Barbosa A, Goldstone DC.   +9 more
europepmc   +1 more source

Engineered bacteriophage lysins as novel anti-infectives

Frontiers in Microbiology, 2014
Bacteriophage lysins, the highly evolved special peptidoglycan hydrolases, have long been demonstrated to be an effective enzybiotics in various infectious models. The modular structure of lysins makes it possible to design bioengineered lysins that have
hang eyang, junping eyu, Hongping eWei
doaj   +1 more source

Antibacterial and anti-biofilm activity of diarylureas against Enterococcus faecium by suppressing the gene expression of peptidoglycan hydrolases and adherence. [PDF]

Front Microbiol, 2022
Xie Y, Wang L, Yang Y, Zha L, Zhang J, Rong K, Tang W, Zhang J.   +7 more
europepmc   +1 more source

From discovery to potential application: engineering a novel M23 peptidase to combat Listeria monocytogenes

Scientific Reports
Peptidoglycan hydrolases are promising alternatives for combating pathogens due to their specificity and potent bacteriolytic activity. In this study, a novel M23 peptidase from Streptococcus thermophilus NCTC10353, designated StM23, was discovered and ...
Magdalena Kaus-Drobek, Marzena Nowacka, Magdalena Gewartowska, Małgorzata Korzeniowska nee Wiweger, Merete Rusås Jensen, Trond Møretrø, Even Heir, Elżbieta Nowak, Izabela Sabała   +8 more
doaj   +1 more source

Bacterial peptidoglycan (murein) hydrolases

Most bacteria have multiple peptidoglycan hydrolases capable of cleaving covalent bonds in peptidoglycan sacculi or its fragments. An overview of the different classes of peptidoglycan hydrolases and their cleavage sites is provided.
Charlier P, Vollmer W, Joris B, Foster S
core  

Peptidoglycan

, 2019
\ua9 2019, Springer Nature Switzerland AG. The peptidoglycan sacculus is a net-like polymer that surrounds the cytoplasmic membrane in most bacteria. It is essential to maintain the bacterial cell shape and protect from turgor.
Peters K, Pazos M
core