Results 61 to 70 of about 8,551 (180)

An Integrated Engineering Approach to Creating Health‐Modulating Postbiotics

Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Postbiotics have emerged as a promising alternative to live probiotics, offering comparable health benefits while overcoming challenges related to safety, stability, and shelf life. The review addresses current challenges in standardizing postbiotic definitions and production processes, and by outlining future research directions necessary to unlock ...
Michael Leonidas Chikindas, Diana E. Roopchand, Santosh Kumar Tiwari, Liubov S. Sichel, Mukund V. Karwe, Nitin Nitin, Vitor Luis Fagundes, Igor V. Popov, John R. Tagg, Xuanxuan Lu, Svetoslav Dimitrov Todorov   +10 more
wiley   +1 more source

Comparison of Predatory Phenotypes and Genotypes Between Bdellovibrio sp. BIS2 and Bacteriovorax sp. HI3 Isolated From the Same Freshwater Environment

Environmental Microbiology, Volume 28, Issue 1, January 2026.
Bdellovibrio and like organisms (BALOs) have gained attraction owing to their ecological and practical significance. This study comparatively investigated two BALO strains from the same freshwater pond, Bdellovibrio sp. BIS2 and Bacteriovorax sp. HI3, and revealed significant variation in their predatory behaviours and associated genetic profiles ...
Tomomi Sugiyama, Tsubasa Kojima, Naoki A. Uemura, Daisuke Nakane, Hideo Dohra, Daisuke Inoue, Michihiko Ike   +6 more
wiley   +1 more source

O-Glycosylation as a Novel Control Mechanism of Peptidoglycan Hydrolase Activity [PDF]

Journal of Biological Chemistry, 2013
Acm2, the major autolysin of Lactobacillus plantarum, is a tripartite protein. Its catalytic domain is surrounded by an O-glycosylated N-terminal region rich in Ala, Ser, and Thr (AST domain), which is of low complexity and unknown function, and a C-terminal region composed of five SH3b peptidoglycan (PG) binding domains.
Rolain, Thomas, Bernard, Elvis, Beaussart, Audrey, Degand, Herve, Courtin, Pascal, Egge-Jacobsen, Wolfgang, Bron, Peter A., Morsomme, Pierre, Kleerebezem, Michiel, Chapot-Chartier, Marie-Pierre, Dufrene, Yves F., Hols, Pascal   +11 more
openaire   +5 more sources

Novel Phage Lysin Abp013 against Acinetobacter baumannii

Antibiotics, 2022
As antimicrobial resistance (AMR) continues to pose an ever-growing global health threat, propelling us into a post-antibiotic era, novel alternative therapeutic agents are urgently required. Lysins are bacteriophage-encoded peptidoglycan hydrolases that
Joash Jun Keat Chu, Wee Han Poh, Nabilah Taqiah Binte Hasnuddin, En Yi Hew, Linh Chi Dam, Abbas El Sahili, Scott A. Rice, Boon Chong Goh   +7 more
doaj   +1 more source

Probiotic Development Strategy Centered on Stability and Regulatory Considerations

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT The development of probiotic strains has become a major focus in both academic and industrial research, driven by their health benefits and growing consumer demand. However, functional outcomes demonstrated under laboratory conditions often fail to align with the stability and large‐scale performance required for industrial applications ...
Hye Kim, Md Ariful Haque, Md Abdur Razzak, Min Ji Jang, Sehyeon Song, Seockmo Ku   +5 more
wiley   +1 more source

Identification of Mur, an Atypical Peptidoglycan Hydrolase Derived fromLeuconostoc citreum [PDF]

Applied and Environmental Microbiology, 2001
ABSTRACTA gene encoding a protein homologous to known bacterialN-acetyl-muramidases has been cloned fromLeuconostoc citreumby a PCR-based approach. The encoded protein, Mur, consists of 209 amino acid residues with a calculated molecular mass of 23,821 Da including a 31-amino-acid putative signal peptide.
Cibik, R., Tailliez, Patrick, Langella, Philippe, Chapot Chartier, Marie-Pierre   +3 more
openaire   +4 more sources

Identification of the chain-dispersing peptidoglycan hydrolase LytB of Streptococcus gordonii. [PDF]

PLoS ONE, 2017
Bacterial cell division ends with the separation of the daughter cells, a process that requires peptidoglycan hydrolases (PGHs). Bacteria lacking cell separating PGHs are impaired in cell separation with the formation of long chains or clusters.
Riccardo Arrigucci, Gianni Pozzi
doaj   +1 more source

Characterisation of a Novel Jumbo Lytic Aeromonas dhakensis Bacteriophage P19 and Its Endolysin

Microbial Biotechnology, Volume 19, Issue 1, January 2026.
A jumbo, lytic myovirus phage P19 against multidrug‐resistant (MDR) Aeromonas dhakensis was isolated from river water. P19 demonstrated robust lytic activity, high thermal and pH stability (pH 6–10, up to 60°C), and no genes associated with lysogeny, virulence or antimicrobial resistance. ORF_358 of P19 encodes for T4‐type lysozyme.
Farhat Ansari, Vandan Nagar
wiley   +1 more source

Bacterial autolysins trim cell surface peptidoglycan to prevent detection by the Drosophila innate immune system

eLife, 2014
Bacteria have to avoid recognition by the host immune system in order to establish a successful infection. Peptidoglycan, the principal constituent of virtually all bacterial surfaces, is a specific molecular signature recognized by dedicated host ...
Magda Luciana Atilano, Pedro Matos Pereira, Filipa Vaz, Maria João Catalão, Patricia Reed, Inês Ramos Grilo, Rita Gonçalves Sobral, Petros Ligoxygakis, Mariana Gomes Pinho, Sérgio Raposo Filipe   +9 more
doaj   +1 more source

Determining bacteriophage endopeptidase activity using either fluorophore-quencher labeled peptides combined with liquid chromatography-mass spectrometry (LC-MS) or Förster resonance energy transfer (FRET) assays. [PDF]

PLoS ONE, 2017
The necessity of identifying novel methods to combat infections caused by antibiotic resistant bacteria is increasing each year. Recent advancements in the development of peptidoglycan hydrolases (e.g. lysins) from bacterial viruses (bacteriophages) have
Rolf Lood, Henrik Molina, Vincent A Fischetti   +2 more
doaj   +1 more source