Results 71 to 80 of about 8,626 (154)

Decoding Akkermansia muciniphila Effector Biology: From Microbial Molecules to Host Outcomes

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Schematic overview of the proposed gut–brain axis mechanisms linking Akkermansia muciniphila to host outcomes. A. muciniphila‐derived signals, including SCFAs and P9/GLP‐1‐related endocrine pathways, may influence epithelial barrier integrity, inflammatory responses, systemic immune signaling, and neural communication through the enteric nervous system,
Amir Arsalan Ghahari, Ainur Sadykova, Salim Davlatov, Mukaddas Xusanova, Gulrukh Indiaminova, Furkat Sobirov, Mirzamakhmud Shadmanov, Umidjon Maxamatov, Patkhiddin Nishonov, Seyed Davar Siadat   +9 more
wiley   +1 more source

Phage Endolysin: A Way To Understand A Binding Function Of C-Terminal Domains A Mini Review

Nova Biotechnologica et Chimica, 2015
Endolysins are bacteriophage-encoded peptidoglycan hydrolases, which are synthesized in the end of phage reproduction cycle, in an infected host cell. Usually, for endolysins from phages that infect Gram-positive bacteria, a modular structure is typical.
Jarábková Veronika, Tišáková Lenka, Godány Andrej   +2 more
doaj   +1 more source

Mechanisms of Resistance, Insights From Case Reports, and Future Prospects in Mycobacteriophage Therapy

Journal of the Royal Society of New Zealand, Volume 56, Issue 4, August 2026.
Evolution of drug‐resistant mycobacterial infections warrants renewed efforts in identifying more efficient preventive and control strategies as well as alternative treatment options. Interest in phage therapy is regaining significant traction, especially in cases of failed conventional therapy.
Buhari Yusuf, Abdul Malik, Md Shah Alam, Lijie Li, Haftay Abraha Tadesse, Aweke Mulu Belachew, Cuiting Fang, Xirong Tian, Htin Lin Aung, Shuai Wang, Tianyu Zhang   +10 more
wiley   +1 more source

Temperature-dependent regulation of bacterial cell division hydrolases by the coordinated action of a regulatory RNA and the ClpXP protease

The Cell Surface
A defining feature of bacteria is the peptidoglycan cell wall which provides structural integrity and prevents osmotic lysis. While peptidoglycan hydrolases are required for daughter cell separation, dysregulated cell wall degradation may result in cell ...
Viktor H. Mebus, Larissa M. Busch, Morten Børre, Tobias K. Nielsen, Martin Saxtorph Bojer, Camilla Henriksen, Maria D. Barbuti, Danae M. Angeles, Kamilla Brejndal, Stephan Michalik, Manuela Gesell Salazar, Morten Kjos, Uwe Völker, Birgitte H. Kallipolitis, Dorte Frees   +14 more
doaj   +1 more source

The Plant Pathogen Xanthomonas campestris pv. campestris Exploits N-Acetylglucosamine during Infection

mBio, 2014
N-Acetylglucosamine (GlcNAc), the main component of chitin and a major constituent of bacterial peptidoglycan, is present only in trace amounts in plants, in contrast to the huge amount of various sugars that compose the polysaccharides of the plant cell
Alice Boulanger, Claudine Zischek, Martine Lautier, Stevie Jamet, Pauline Rival, Sébastien Carrère, Matthieu Arlat, Emmanuelle Lauber   +7 more
doaj   +1 more source

Putative Mechanisms for Initial Reaction of Anaerobic Benzene Degradation Presumably Involving a Flavoprotein

Environmental Microbiology, Volume 28, Issue 8, August 2026.
Anaerobic biodegradation of benzene by sulphate‐reducing strain BzS1 was studied by combining genomics, differential proteomics and targeted metabolite analyses. Strain BzS1 has an exceptionally streamlined metabolism. A highly abundant heterotrimeric flavoprotein may add benzene to either enolpyruvate or glutaconyl‐CoA followed by channelling into the
Florin Musat, Lars Wöhlbrand, Rene Jarling, Michael Kube, Niculina Musat, Patrick Becker, Stefan Bruns, Richard Reinhardt, Rudolf Amann, Friedrich Widdel, Heinz Wilkes, Ralf Rabus   +11 more
wiley   +1 more source

A new regulator of the Staphylococcus aureus peptidoglycan hydrolase Sle1

PLOS Genetics
Regulation of peptidoglycan hydrolases is crucial for bacterial cell integrity, growth and division. In the bacterial pathogen Staphylococcus aureus , the amidase Sle1 is a key autolysin required for septum splitting and daughter cell separation.
Helena Veiga, Adrian Izquierdo-Martinez, Leonor B. Marques, Mariana G. Pinho   +3 more
openaire   +2 more sources

A novel peptidoglycan deacetylase modulates daughter cell separation in E. coli.

PLoS Genetics
Peptidoglycan hydrolases facilitate bacterial cell wall growth by creating space for insertion of new material and allowing physical separation of daughter cells.
Víctor M Hernández-Rocamora, Alessandra M Martorana, Aitana Belloso, Daniel Ballesteros, Marta Zaccaria, Amilcar J Perez, Bogdan I Iorga, David Abia, Joe Gray, Eefjan Breukink, Jie Xiao, Manuel Pazos, Alessandra Polissi, Waldemar Vollmer   +13 more
doaj   +1 more source

A Single Dual-Function Enzyme Controls the Production of Inflammatory NOD Agonist Peptidoglycan Fragments by Neisseria gonorrhoeae

mBio, 2017
Neisseria gonorrhoeae gonococcus (GC) is a Gram-negative betaproteobacterium and causative agent of the sexually transmitted infection gonorrhea. During growth, GC releases lipooligosaccharide (LOS) and peptidoglycan (PG) fragments, which contribute ...
Jonathan D. Lenz, Kathleen T. Hackett, Joseph P. Dillard   +2 more
doaj   +1 more source

Fungicide Drives De Novo Evolution of Multidrug Resistance in the Plant Growth Promoting Rhizobacterium, Pseudomonas fluorescens

Evolutionary Applications, Volume 19, Issue 8, August 2026.
ABSTRACT Soil microbial communities underpin key ecosystem processes, including plant health, nutrient cycling and primary productivity. In agricultural soils, beneficial soil bacteria are often exposed to multiple stressors simultaneously, including fungicides, antibiotics, and warming temperatures. Despite their ecological importance, little is known
Matthew Kelbrick, James P. J. Hall, Siobhán O'Brien   +2 more
wiley   +1 more source