Results 71 to 80 of about 14,172 (195)

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

In Vitro Characterization of Technological and Health‐Promoting Properties of Enterocin Producing Lactic Acid Bacteria From Camel Milk and Its Suitability as a Dairy Starter

Food Chemistry International, EarlyView.
Enterocin‐producing Enterococcus faecium RSCUDR7 from camel milk exhibited strong probiotic and antimicrobial properties, along with stability in skim milk. Its suitability as a safe and effective dairy starter highlights its potential for developing functional probiotic dairy products.
Rahul Singhal, Kamalesh Kumar Meena, Manvik Joshi, Lokesh Gupta, Sunil Meena   +4 more
wiley   +1 more source

Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC [PDF]

Proceedings of the National Academy of Sciences, 2014
Significance During growth and division, bacterial cells partition the cell wall to daughter cells, but the “inside-out” signals that regulate peptidoglycan (PG) hydrolysis are not well understood. Our studies of mycobacterial proteins achieve in vitro reconstitution of the regulation of the PG hydrolase, RipC, by the FtsX extracellular ...
Mavrici, Daniela, Marakalala, Mohlopheni J., Holton, James M., Prigozhin, Daniil M., Gee, Christine L., Zhang, Yanjia J., Rubin, Eric J., Alber, Tom   +7 more
openaire   +4 more sources

Comprehensive and Comparative Transcriptional Profiling of the Cell Wall Stress Response in Bacillus subtilis

Molecular Microbiology, EarlyView.
Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang, Charlène Cornilleau, Lena Friebel, Sarah Spitzner, Raphael R. Müller, Doreen Meier, Pierre Flores, Cyprien Guérin, Pierre Nicolas, Diana Wolf, Vincent Fromion, Rut Carballido‐López, Thorsten Mascher   +12 more
wiley   +1 more source

Staphylococcus aureus cell wall structure and dynamics during host-pathogen interaction.

PLoS Pathogens, 2021
Peptidoglycan is the major structural component of the Staphylococcus aureus cell wall, in which it maintains cellular integrity, is the interface with the host, and its synthesis is targeted by some of the most crucial antibiotics developed.
Joshua A F Sutton, Oliver T Carnell, Lucia Lafage, Joe Gray, Jacob Biboy, Josie F Gibson, Eric J G Pollitt, Simone C Tazoll, William Turnbull, Natalia H Hajdamowicz, Bartłomiej Salamaga, Grace R Pidwill, Alison M Condliffe, Stephen A Renshaw, Waldemar Vollmer, Simon J Foster   +15 more
doaj   +1 more source

Identification of a New Family of Enzymes with Potential \u3cem\u3eO\u3c/em\u3e-acetylpeptidoglycan esterase activity in both Gram-positive and Gram-negative bacteria [PDF]

, 2005
Background: The metabolism of the rigid bacterial cell wall heteropolymer peptidoglycan is a dynamic process requiring continuous biosynthesis and maintenance involving the coordination of both lytic and synthetic enzymes.
Clarke, Anthony J., Pfeffer, John M., Weadge, Joel T.   +2 more
core   +1 more source

Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation [PDF]

, 2020
The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus. Deletion of a gene encoding a putative deacetylase, Agd3, leads to defects in GAG deacetylation, biofilm formation, and ...
A Ghafoor, A Morin, AB Boraston, AW Blake, C Bundalovic-Torma, C Guerrero, C Ryder, C Steentoft, C Vuong, CM Payne, Collaborative Computational Project Number 4., CS Cummins, DC Sheppard, DE Blair, DE Blair, DJ Little, DJ Little, DJ Little, E Andrés, E Potterton, EN Kitova, F Le Mauff, F Sievers, FN Gravelat, FN Gravelat, GB Whitfield, GD Brown, GM Sheldrick, GM Sheldrick, H Aragunde, H Ashkenazy, H Ostapska, H Takada, H Zakariassen, J Hoßbach, J Sun, JA Jorge, JA Jorge, JJ Distler, JJ Tesmer, JL Reissig, JW Jensen, K Miyazawa, K Mizutani, KM Colvin, LA Kelley, LK Jennings, LS Marmont, M Gonzalez, M Oda, M Strong, MD Winn, MJ Lee, MJ Lee, MM Shaik, N Nwe, NA Baker, NC Bamford, NC Bamford, P Emsley, P Ruperez, P Vasseur, PC Bardalaye, PD Adams, PD Adams, RC Edgar, RE Lewis, S Jana, S Kaur, S Kumar, SC Potter, SF Altschul, T Fontaine, T Inoue, V Pokrovskaya, VE Fadouloglou, VK Köseoğlu, W Vollmer, W Wang, X Wang, X-L Li, Y Araki, Y Itoh, Y Kidani, Y Kidani   +84 more
core   +3 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

O-Glycosylation as a Novel Control Mechanism of Peptidoglycan Hydrolase Activity [PDF]

Journal of Biological Chemistry, 2013
Acm2, the major autolysin of Lactobacillus plantarum, is a tripartite protein. Its catalytic domain is surrounded by an O-glycosylated N-terminal region rich in Ala, Ser, and Thr (AST domain), which is of low complexity and unknown function, and a C-terminal region composed of five SH3b peptidoglycan (PG) binding domains.
Rolain, Thomas, Bernard, Elvis, Beaussart, Audrey, Degand, Herve, Courtin, Pascal, Egge-Jacobsen, Wolfgang, Bron, Peter A., Morsomme, Pierre, Kleerebezem, Michiel, Chapot-Chartier, Marie-Pierre, Dufrene, Yves F., Hols, Pascal   +11 more
openaire   +5 more sources

Phage-derived peptidoglycan degrading enzymes: challenges and future prospects for in vivo therapy [PDF]

, 2018
Peptidoglycan degrading enzymes are of increasing interest as antibacterial agents, especially against multi-drug resistant pathogens. Herein we present a review about the biological features of virion-associated lysins and endolysins, phage-derived ...
Azeredo, Joana, Oliveira, Hugo, São-José, Carlos   +2 more
core   +2 more sources