Results 41 to 50 of about 14,095 (224)
Peptidomimetics in cancer targeting
Molecular Medicine, 2022 AbstractThe low efficiency of treatment strategies is one of the main obstacles to developing cancer inhibitors. Up to now, various classes of therapeutics have been developed to inhibit cancer progression. Peptides due to their small size and easy production compared to proteins are highly regarded in designing cancer vaccines and oncogenic pathway ...
Mohammad Mahmoudi Gomari +9 more
openaire +3 more sources
Work flow of peptidomimetic design and selection.
, 2015 Work flow of peptidomimetic design and selection.
Sonali Gopichand Chavan (713710) +1 more
core +1 more source
Design, Synthesis, and Antitumor Activities Study of Stapled A4K14-Citropin 1.1 Peptides
Frontiers in Chemistry, 2020 A4K14-citropin 1.1 is a structurally optimized derivative derived from amphibians' skin secreta peptide Citropin, which exhibits broad biological activities.
Nan Wang +7 more
doaj +1 more source
Structures of peptidomimetic ligands 1 and 2.
, 2019 Structures of peptidomimetic ligands 1 and 2.
Donatella Potenza (1863193) +8 more
core +1 more source
, 2021 A new β-turn inducer peptidomimetic incorporating 1-amino-1-aminomethylcyclohexane (compound 3) was synthetized and structurally studied. It was established that there is a rapid conformational equilibrium between the expected β-turn inducer ...
Juan C. Estévez +4 more
core +1 more source
Journal of Pharmacological Sciences, 2022 Protein–protein interactions (PPI) of co-stimulatory molecules CD2-CD58 are important in the early stage of an immune response, and increased expression of these co-stimulatory molecules is observed in the synovial region of joints in rheumatoid ...
Achyut Dahal +7 more
doaj +1 more source
Cross-resistance between peptidomimetic 1 and 2.
, 2013 Association between Minimum Inhibitory Concentration (MIC) for peptidomimetic 1 and peptidomimetic 2 against lineage no. 2 (black circles) and lineage no. 5 (white circles). E. coli ATCC 25922 MIC is highlighted with an asterisk (i.e.
Line Hein-Kristensen (454385) +3 more
core +1 more source
Peptidomimetic Polyurethanes Disrupt Surface Established Bacterial Biofilms and Prevent Biofilm Formation [PDF]
, 2021 Over 80% of all chronic bacterial infections in humans are associated with biofilms, which are surface-associated bacterial communities encased within a secreted exopolysaccharide matrix that can provide resistance to environmental and chemical insults ...
Abraham, Joy +4 more
core +1 more source
IRAP Inhibitors: M1-Aminopeptidase Family Inspiration
Frontiers in Pharmacology, 2020 The insulin regulated aminopeptidase (IRAP) has been proposed as an important therapeutic target for indications including Alzheimer’s disease and immune disorders.
Nicholas Barlow, Philip E. Thompson
doaj +1 more source
Molecules, 2022 Protein N-terminal methyltransferase 1 (NTMT1) recognizes a unique N-terminal X-P-K/R motif (X represents any amino acid other than D/E) and transfers 1–3 methyl groups to the N-terminal region of its substrates.
Guangping Dong +4 more
doaj +1 more source