Results 51 to 60 of about 14,095 (224)
Advanced Science, EarlyView.Receptor‐triggered supramolecular self‐assembly converts monovalent antibody‐recruiting molecules into multivalent platforms directly on cancer cell membranes. The resulting fibrillar assemblies present clustered haptens that efficiently recruit endogenous antibodies, enabling selective complement‐mediated immune killing of EGFR‐positive cancer cells ...
Yihui Wang +6 more
wiley +1 more source
Self-Assembling Peptidomimetic Monolayer Nucleates Oriented CdS Nanocrystals
, 2016 Self-Assembling Peptidomimetic Monolayer Nucleates Oriented CdS ...
Haimanot Bekele (3007545) +2 more
core +1 more source
SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition
Advanced Science, EarlyView.The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang +9 more
wiley +1 more source
An Artificial Antiparallel β-Sheet Containing a New Peptidomimetic Template
, 2016 An Artificial Antiparallel β-Sheet Containing a New Peptidomimetic ...
James S. Nowick (1272555) +3 more
core +1 more source
Novel Retro-Inverso Peptide Antibiotic Efficiently Released by a Responsive Hydrogel-Based System
Biomedicines, 2022 Topical antimicrobial treatments are often ineffective on recalcitrant and resistant skin infections. This necessitates the design of antimicrobials that are less susceptible to resistance mechanisms, as well as the development of appropriate delivery ...
Angela Cesaro +7 more
doaj +1 more source
Synthesis of an IGD peptidomimetic with motogenic activity
, 2005 Rational design and synthesis of an IGD peptidomimetic substrate with significant motogenic ...
Ellis, Ian R.; id_orcid +7 more
core +1 more source
Peptidomimetic and Non- Peptidomimetic Derivatives as Possible SARS-CoV-2 Main Protease (Mpro) Inhibitors [PDF]
, 2021 To design novel inhibitors of the SARS-CoV-2 main protease (Mpro), we investigated the binding mode of the recently reported α-ketoamide inhibitors of this enzyme.
Al Awadh, Mohammed A +8 more
core
A library of copper-peptide/peptidomimetic complexes to explore the effect of ligand framework modification on electrocatalytic water oxidation [PDF]
Inspired by the process of water oxidation during photosynthesis, researchers have developed mononuclear and polynuclear transition metal complexes as homogeneous water oxidation catalysts.
Molly , McAuliffe +11 more
core +2 more sources
Antibiotics, 2023 The development of potent antiviral agents is of utmost importance to combat the global burden of viral infections. Traditional antiviral drug development involves targeting specific viral proteins, which may lead to the emergence of resistant strains ...
Umme Laila Urmi +6 more
doaj +1 more source
A cyclic carbo-isosteric penta-depsipeptide: cyclo(Phe1–d-Ala2–Gly3–Phe4–APO5)
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound, cyclo(Phe1–d-Ala2–Gly3–Phe4–APO5), C26H32N4O5, is the minor diastereoisomer of a cyclic penta-peptidomimetic analogue containing a novel 2-aminopropyl lactone (APO) motif, which displays the same number of atoms as the native amino ...
Stéphanie M. Guéret, Trixie Wagner
doaj +1 more source