Results 1 to 10 of about 1,691 (160)
A Peptoid-Based Fluorescent Sensor for Cyanide Detection
Molecules, 2016 Peptoids, N-substituted glycine oligomers, are versatile peptidomimetics with diverse biomedical applications. However, strategies to the development of novel fluorescent peptoids as chemical sensors have not been extensively explored, yet.
Bumhee Lim, Jeeyeon Lee
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Addressing MRSA infection and antibacterial resistance with peptoid polymers
Nature Communications, 2021 Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacterial ...
Jiayang Xie +15 more
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Identification of cannabinoid-sensitive and -resistant oral bacteria [PDF]
Frontiers in MicrobiologyMarijuana, an emerging risk factor for periodontitis, contains multiple potent antibacterials, particularly the phytocannabinoids. Microbial dysbiosis is a hallmark of this destructive oral disease. We examined a panel of oral bacteria for susceptibility
David A. Scott +8 more
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A Peptoid Ribbon Secondary Structure [PDF]
Angewandte Chemie - International Edition, 2013 foldamers that have been shown to possess numerous biological functions and could find use in a range of fundamental and applied contexts as bio-inspired materials. Peptoids are highly attractive scaffolds for such purposes, as their non-native backbones are resistant to proteolytic degradation and their straightforward, modular synthesis enables the ...
J Aaron Crapster +2 more
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A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure [PDF]
Frontiers in PharmacologyBackgroundAlpha-calcitonin gene-related peptide (α-CGRP) is a cardioprotective neuropeptide. However, due to low bioavailability, its use as a therapeutic agent is limited.
Ambrish Kumar +4 more
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Topology-Dependent Antifreeze Properties of Biomimetic Linear and Star-Shaped Peptoids [PDF]
BiomimeticsDeveloping safe and efficient cryoprotectants is critical for effective cryopreservation in biomedical applications. Inspired by natural antifreeze proteins (AFPs), a series of linear and star-shaped peptoids featuring isopropanol side chains to mimic ...
Lei Feng +7 more
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Functionalized Surface Coatings for Rigid Contact Lenses [PDF]
Journal of Functional BiomaterialsThis research evolves into a comparative study of three different phenolic composites as coatings for rigid contact lenses, with a particular emphasis on enhancing their antifouling properties and hydrophobicity.
Roeya Refaei +8 more
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Cis-trans isomerization of peptoid residues in the collagen triple-helix
Nature Communications, 2023 Cis-peptide bonds are rare in proteins, and building blocks less favorable to the trans-conformer have been considered destabilizing. Although proline tolerates the cis-conformer modestly among all amino acids, for collagen, the most prevalent proline ...
Rongmao Qiu +7 more
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Applying a Hydrophilic Modified Hollow Fiber Membrane to Reduce Fouling in Artificial Lungs
Separations, 2021 Membranes for use in high gas exchange lung applications are riddled with fouling. The goal of this research is to create a membrane that can function in an artificial lung until the actual lung becomes available for the patient.
Nawaf Alshammari +2 more
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Peptoid microsphere coatings to improve performance in sandwich ELISA microarrays
Sensing and Bio-Sensing Research, 2021 Enzyme-linked immunosorbent assay (ELISA) microarray performance is limited by low assay sensitivity and dynamic range. Increasing the surface area for reagent binding can help to improve performance, but standard techniques such as roughening the ...
Jesse L. Roberts +2 more
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