Evaluation of Phage Display Discovered Peptides as Ligands for Prostate-Specific Membrane Antigen (PSMA) [PDF]
, 2013 The aim of this study was to identify potential ligands of PSMA suitable for further development as novel PSMA-targeted peptides using phage display technology. The human PSMA protein was immobilized as a target followed by incubation with a 15-mer phage
A Ghosh +48 more
core +16 more sources
Ugi multicomponent reaction to prepare peptide–peptoid hybrid structures with diverse chemical functionalities [PDF]
, 2018 Monodisperse sequenced peptides and peptoids present unique nano-structures based on their self-assembled secondary and tertiary structures. However, the generation of peptide and peptoid hybrid oligomers in a sequence-defined manner via Ugi ...
Azevedo, Helena S. +12 more
core +1 more source
Development of Peptoid-Based Ligands for the Removal of Cadmium from Biological Media. [PDF]
, 2015 Cadmium poisoning poses a serious health concern due to cadmiums increasing industrial use, yet there is currently no recommended treatment. The selective coordination of cadmium in a biological environment-i.e.
Francis, Matthew +2 more
core +2 more sources
Frontiers in Molecular Neuroscience, 2021 Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases with irreversible damage of the brain and a continuous pathophysiological process.
Yuxin Guo +6 more
doaj +1 more source
Solid-Phase Synthesis of N-Substituted Glycine Oligomers (α‑Peptoids) and Derivatives
Molecules, 2010 Peptoids (N-substituted polyglycines and extended peptoids with variant backbone amino-acid monomer units) are oligomeric synthetic polymers that are becoming a valuable molecular tool in the biosciences.
Rodney J. Ouellette, Adrian S. Culf
doaj +1 more source
Click mediated synthesis of functionalized glycolipids with peptide-peptoid linkages [PDF]
Journal of the Serbian Chemical Society, 2023 The present work describes the synthesis of a new class of glycolipids with systematic variations in the linkage region, as well as in the aglycon part using Cu(I) catalyzed click reaction.
Singhamahapatra Anadi +5 more
doaj +1 more source
Molecules, 2021 Peptoids (oligo N-substituted glycines) are peptide analogues, which can be designed to mimic host antimicrobial peptides, with the advantage that they are resistant to proteolytic degradation.
Jamie Toole +5 more
doaj +1 more source
Surface-immobilised antimicrobial peptoids [PDF]
Biofouling, 2008 Surface modification techniques that create surfaces capable of killing adherent bacteria are promising solutions to infections associated with implantable medical devices. Antimicrobial (AM) peptoid oligomers (ampetoids) that were designed to mimic helical AM peptides were synthesised with a peptoid spacer chain to allow mobility and an adhesive ...
Andrea R, Statz +4 more
openaire +2 more sources
Discovery of Stable and Selective Antibody Mimetics from Combinatorial Libraries of Polyvalent, Loop-Functionalized Peptoid Nanosheets. [PDF]
, 2019 The ability of antibodies to bind a wide variety of analytes with high specificity and high affinity makes them ideal candidates for therapeutic and diagnostic applications. However, the poor stability and high production cost of antibodies have prompted
Abate, Adam R +19 more
core +1 more source
Metalloporphyrin Dimers Bridged by a Peptoid Helix: Host-Guest Interaction and Chiral Recognition
Molecules, 2018 Co-facial porphyrins have been designed to construct porphyrin tweezers with versatile molecular recognition capabilities. In this study, we synthesized metalloporphyrin⁻peptoid conjugates (MPPCs) displaying two metalloporphyrins on a peptoid ...
Yen Jea Lee, Boyeong Kang, Jiwon Seo
doaj +1 more source