Results 21 to 30 of about 3,952 (212)
Molecules, 2021 Peptoids (oligo N-substituted glycines) are peptide analogues, which can be designed to mimic host antimicrobial peptides, with the advantage that they are resistant to proteolytic degradation.
Jamie Toole +5 more
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Structure–Function Relationship within Cu-Peptoid Electrocatalysts for Water Oxidation
Inorganics, 2023 Water oxidation (WO) is the first step in the water-splitting process aiming at the production of hydrogen as a green renewable fuel. To successfully perform WO, potent strategies for overcoming the high energetic barrier and slow kinetics of this ...
Guilin Ruan +2 more
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Peptoid-Based Microsphere Coatings for Biomaterial Applications [PDF]
, 2021 Peptoids are peptidomimetic oligomers that predominantly harness similarities to peptides for biomimetic functionality. The incorporation of chiral, aromatic side chains in the peptoid sequence allows for the formation of distinct secondary structures ...
Roberts, Jesse Leland
core +3 more sources
Metalloporphyrin Dimers Bridged by a Peptoid Helix: Host-Guest Interaction and Chiral Recognition
Molecules, 2018 Co-facial porphyrins have been designed to construct porphyrin tweezers with versatile molecular recognition capabilities. In this study, we synthesized metalloporphyrin⁻peptoid conjugates (MPPCs) displaying two metalloporphyrins on a peptoid ...
Yen Jea Lee, Boyeong Kang, Jiwon Seo
doaj +1 more source
Frontiers in Microbiology, 2020 Tuberculosis (TB) results in both morbidity and mortality on a global scale. With drug resistance on the increase, there is an urgent need to develop novel anti-mycobacterials.
Jasmeet Singh Khara +8 more
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Molecules, 2018 Antimicrobial peptides (AMPs) hold promise as the next generation of antimicrobial agents, but often suffer from rapid degradation in vivo. Modifying AMPs with non-proteinogenic residues such as peptoids (oligomers of N-alkylglycines) provides the ...
Ines Greco +8 more
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A peptoid interleukin‐15 receptor antagonist suppresses inflammation and arthritis in mice
Clinical & Translational Immunology, 2022 Objective To discover a novel peptoid antagonist that targets the interleukin‐15 (IL‐15) receptor and to evaluate its therapeutic efficacy in the treatment of inflammation and arthritis. Methods A new compound (IFRA3, interleukin‐15 receptor antagonist 3)
Kwang Bog Cho +11 more
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Multi-component click strategy for 1,4-dithiane-2,5-diol based peptoid–triazole conjugates: a combined synthetic and computational studyMulti-component click strategy for 1,4-dithiane-2,5-diol based peptoid–triazole conjugates: a combined synthetic and computational study [PDF]
Royal Society Open SciencePeptoids and triazoles are N-based organic compounds that have gained immense attention owing to their wide range of applications in pharmaceutical chemistry, drug discovery and materials science.
Hina Anwar, Akbar Ali
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Molecules, 2007 Two new groups of cholane-peptoid hybrid macrocycles were produced by implementing novel combinations of the MiB methodology. Steroid-based hybrid macrolactams including heterocycle and aryl moieties were obtained by utilizing cholanic dicarboxylic acids
Ludger A. Wessjohann, Daniel G. Rivera
doaj +1 more source
Review: Structure-Activity Relationship of Antimicrobial Peptoids
Pharmaceutics, 2023 Due to their broad-spectrum activity against Gram-negative and Gram-positive bacteria, natural antimicrobial peptides (AMPs) and their synthetic analogs have emerged as prospective therapies for treating illnesses brought on by multi-drug resistant ...
Priscilla L. Nyembe +2 more
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