Results 41 to 50 of about 3,952 (212)
Organic Letters, 2008 The first synthesis of functionalized -peptoid macrocycles is reported. X-ray crystallographic structure of tetramer 9 reveals a C2-symmetrical derivative with unexpected all-cis-amide bonds and spatial disposition of the appendages toward the two opposite faces of the ring. Quantum calculations suggest that 9 is locked in this layout.
Roy, Olivier +4 more
openaire +2 more sources
Insights into the Biomimetic Synthesis of 2D ZnO Nanomaterials through Peptoid Engineering
, 2023 Achieving predictable biomimetic crystallization using sequence-defined synthetic molecules in mild conditions represents a long-standing challenge in materials synthesis.
Wenchao Yang (475707) +13 more
core +1 more source
Molecules, 2019 Methicillin-resistant Staphylococcus pseudintermedius (MRSP) constitutes an emerging health problem for companion animals in veterinary medicine. Therefore, discovery of novel antimicrobial agents for treatment of Staphylococcus-associated canine ...
Ines Greco +8 more
doaj +1 more source
The Effect of Hydrophilic Headgroup Chemistry on Peptoid‐Directed Mineralization of CaCO3
Advanced Functional Materials, EarlyView.Amphiphilic peptoids alter the pathway and outcome of calcium carbonate crystallization, which progresses through amorphous calcium carbonate (ACC) to vaterite to calcite rhombs in the absence of peptoids. In contrast, amine‐terminated peptoids produce vaterite disks and carboxyl‐terminated peptoids produce calcite mesocrystals.
Biao Jin +5 more
wiley +1 more source
Chemical structures of (A) peptoid 1 and (B) the peptoid monomers.
, 2016 Chemical structures of (A) peptoid 1 and (B) the peptoid monomers.
Annelise E. Barron (393021) +7 more
core +1 more source
Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee +5 more
wiley +2 more sources
Beilstein Journal of Organic Chemistry, 2012 Two syntheses of natural viridic acid, an unusual triply N-methylated peptide with two anthranilate units, are presented. The first one is based on peptide-coupling strategies and affords the optically active natural product in 20% overall yield over six
Ricardo A. W. Neves Filho +3 more
doaj +1 more source
Advanced Science, EarlyView.This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun +12 more
wiley +1 more source
Bulletin of the Korean Chemical Society, EarlyView.Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon +3 more
wiley +1 more source
Advanced Science, 2023 Antimicrobial peptides (AMPs) are promising therapeutics in the fight against multidrug‐resistant bacteria. As a mimic of AMPs, peptoids with N‐substituted glycine backbone have been utilized for antimicrobials with resistance against proteolytic ...
Minsang Kim +12 more
doaj +1 more source