Results 51 to 60 of about 5,562 (217)
Molecules, 2019 Methicillin-resistant Staphylococcus pseudintermedius (MRSP) constitutes an emerging health problem for companion animals in veterinary medicine. Therefore, discovery of novel antimicrobial agents for treatment of Staphylococcus-associated canine ...
Ines Greco +8 more
doaj +1 more source
Orthogonal protection of peptides and peptoids for cyclization by the thiol-ene reaction and conjugation [PDF]
, 2014 Cyclic peptides and peptoids were prepared using the thiol-ene Michael-type reaction. The linear precursors were provided with additional functional groups allowing for subsequent conjugation: an orthogonally protected thiol, a protected maleimide, or an
Elduque Busquets, Xavier +2 more
core +2 more sources
Beilstein Journal of Organic Chemistry, 2012 Two syntheses of natural viridic acid, an unusual triply N-methylated peptide with two anthranilate units, are presented. The first one is based on peptide-coupling strategies and affords the optically active natural product in 20% overall yield over six
Ricardo A. W. Neves Filho +3 more
doaj +1 more source
Characterization of Novel Antimicrobial Peptoids [PDF]
Antimicrobial Agents and Chemotherapy, 1999 ABSTRACT Peptoids differ from peptides in that peptoids are composed of N-substituted rather than alpha-carbon-substituted glycine units. In this paper we report the in vitro and in vivo antibacterial activities of several antibacterial peptoids discovered by screening combinatorial chemistry libraries for bacterial growth ...
B, Goodson +12 more
openaire +2 more sources
Advanced Science, 2023 Antimicrobial peptides (AMPs) are promising therapeutics in the fight against multidrug‐resistant bacteria. As a mimic of AMPs, peptoids with N‐substituted glycine backbone have been utilized for antimicrobials with resistance against proteolytic ...
Minsang Kim +12 more
doaj +1 more source
Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing [PDF]
, 2018 Staphylococcus aureus is an important pathogen causing infections in humans and animals. Increasing problems with antimicrobial resistance has prompted the development of alternative treatment strategies, including antivirulence approaches targeting ...
Baldry, Mara +8 more
core +2 more sources
Highly stable and tunable peptoid/hemin enzymatic mimetics with natural peroxidase-like activities
Nature Communications, 2022 Peroxidase mimics are currently being investigated as catalysts for lignin depolymerisation. In this article, the authors investigate a class of self-assembled and highly stable peptoid/hemin nanomaterials as peroxidase mimics that are highly stable and ...
Tengyue Jian +7 more
doaj +1 more source
Biotechnology & Biotechnological Equipment, 2019 Bioactive compounds, such as antimicrobial peptides (AMPs), have increasingly been used recently to counteract the rapidly increasing incidence of bacterial resistance to usual antibiotics and chemotherapeutics. In humans, endogenous AMPs are part of the
Meri Amerikova +4 more
doaj +1 more source
Role of Histidine‐Containing Peptoids in Accelerating the Kinetics of Calcite Growth
Advanced Functional Materials, Volume 36, Issue 34, 27 April 2026.Amphiphilic histidine‐containing peptoids mimic carbonic anhydrase (CA) to accelerate calcite step growth. In the presence of Zn2+, they promote the deprotonation of HCO3−, the desolvation of Ca2+, and the reorganization of interfacial hydration layers, thereby reducing the activation barrier for calcite growth.
Mingyi Zhang +5 more
wiley +1 more source
Cancer Nexus, Volume 2, Issue 2, April 2026.ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han +5 more
wiley +1 more source