Results 51 to 60 of about 3,952 (212)

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Antimicrobial activity, mechanism of action, and methods for stabilisation of defensins as new therapeutic agents

Biotechnology & Biotechnological Equipment, 2019
Bioactive compounds, such as antimicrobial peptides (AMPs), have increasingly been used recently to counteract the rapidly increasing incidence of bacterial resistance to usual antibiotics and chemotherapeutics. In humans, endogenous AMPs are part of the
Meri Amerikova, Ivanka Pencheva El-Tibi, Vania Maslarska, Stanislav Bozhanov, Konstantin Tachkov   +4 more
doaj   +1 more source

Highly stable and tunable peptoid/hemin enzymatic mimetics with natural peroxidase-like activities

Nature Communications, 2022
Peroxidase mimics are currently being investigated as catalysts for lignin depolymerisation. In this article, the authors investigate a class of self-assembled and highly stable peptoid/hemin nanomaterials as peroxidase mimics that are highly stable and ...
Tengyue Jian, Yicheng Zhou, Peipei Wang, Wenchao Yang, Peng Mu, Xin Zhang, Xiao Zhang, Chun-Long Chen   +7 more
doaj   +1 more source

Antifouling Glycocalyx-Mimetic Peptoids [PDF]

Journal of the American Chemical Society, 2013
The glycocalyx of the cell is composed of highly hydrated saccharidic groups conjugated to protein and lipid cores. Although components of the glycocalyx are important in cell-cell interactions and other specific biological recognition events, a fundamental role of the glycocalyx is the inhibition of nonspecific interactions at the cell surface ...
Ham, Hyun Ok, Park, Sung Hyun, Kurutz, Josh W, Szleifer, Igal G, Messersmith, Phillip B   +4 more
openaire   +4 more sources

A Solid‐Phase Approach to Chiral C2‐Substituted Cyclen and DOTA‐Like Lanthanoid Ligands

Chemistry – A European Journal, EarlyView.
Chiral C2‐substituted cyclen derivatives have been designed and synthesized from chiral cyclic peptoids. Their conversion into the corresponding DOTA‐type ligands opens new avenues for the development of high‐relaxivity MRI contrast agents. ABSTRACT Magnetic resonance imaging (MRI) is a powerful diagnostic modality that relies on Gd+3‐based contrast ...
Rosaria Schettini, Roberta Napolitano, Alberto Fringuello Mingo, Federica Buonsanti, Giovanni Pierri, Consiglia Tedesco, Chiara Costabile, Giorgio Della Sala, Irene Izzo, Francesco De Riccardis   +9 more
wiley   +1 more source

Characterization of Novel Antimicrobial Peptoids [PDF]

Antimicrobial Agents and Chemotherapy, 1999
ABSTRACT Peptoids differ from peptides in that peptoids are composed of N-substituted rather than alpha-carbon-substituted glycine units. In this paper we report the in vitro and in vivo antibacterial activities of several antibacterial peptoids discovered by screening combinatorial chemistry libraries for bacterial growth ...
B, Goodson, A, Ehrhardt, S, Ng, J, Nuss, K, Johnson, M, Giedlin, R, Yamamoto, W H, Moos, A, Krebber, M, Ladner, M B, Giacona, C, Vitt, J, Winter   +12 more
openaire   +2 more sources

Impact of Monomer Purity on the Acid‐Catalyzed ROP of Sarcosine N‐Carboxyanhydrides: A Comparative Study of Phosgene‐Free Synthetic Routes toward High‐Molecular‐Weight Polysarcosine

Macromolecular Rapid Communications, EarlyView.
A robust, phosgene‐free oxalyl chloride/silyl‐mediated route yields high‐purity sarcosine N‐carboxyanhydride (Sar‐NCA) by eliminating residual impurities that compromise polymerization control. This strategy enables well‐defined, acid‐catalyzed ring‐opening polymerization under ambient conditions, producing polysarcosine with Mn up to 186 kDa and ...
Anna Golunova, Ana Elena Morán Espinoza, Jana Dvořáková, Petr Hezký, Andres de los Santos Pereira, Lenka Kotrchová, Vladimír Proks   +6 more
wiley   +1 more source

Porphyrin–Peptoid Conjugates: Face-to-Face Display of Porphyrins on Peptoid Helices

, 2016
Distance, orientation, and number controlled porphyrin–peptoid conjugates (PPCs) were efficiently synthesized. Cofacial (1, 2, and 4), slipped-cofacial (3), and unstructured (5) arrangements of porphyrins provided distinct optical and electronic ...
Jiyoun Lee (1878409), Young Deok Ahn (1973617), Boyeong Kang (1973614), Solchan Chung (1973611), Jiwon Seo (528884)   +4 more
core   +1 more source

Green and Sustainable Solvents for Solid-Phase Peptoid Synthesis [PDF]

, 2023
Peptoids are a class of sequence-controlled polymers that provide a versatile platform for the design of bioinspired materials. Solid-phase synthetic methods offer absolute control over the polypeptoid sequence and have been optimized to improve ...
Katya Naomi, Marín Vera, Abigail, Clapperton, Helen, Tran, Jon, Babi   +3 more
core   +2 more sources

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source