Review: Structure-Activity Relationship of Antimicrobial Peptoids [PDF]
Pharmaceutics, 2023 Due to their broad-spectrum activity against Gram-negative and Gram-positive bacteria, natural antimicrobial peptides (AMPs) and their synthetic analogs have emerged as prospective therapies for treating illnesses brought on by multi-drug resistant ...
Maya Makatini, Thandokuhle Ntombela
exaly +4 more sources
Peptoids and polyamines going sweet: Modular synthesis of glycosylated peptoids and polyamines using click chemistry [PDF]
Beilstein Journal of Organic Chemistry, 2013 Sugar moieties are present in a wide range of bioactive molecules. Thus, having versatile and fast methods for the decoration of biomimetic molecules with sugars is of fundamental importance.
Frank Hahn +2 more
exaly +3 more sources
Cyclic Octamer Peptoids: Simplified Isosters of Bioactive Fungal Cyclodepsipeptides [PDF]
Molecules, 2018 Cyclic peptoids have recently emerged as an important class of bioactive scaffolds with unique conformational properties and excellent metabolic stabilities.
Giorgio Della Sala +2 more
exaly +4 more sources
Topology-Dependent Antifreeze Properties of Biomimetic Linear and Star-Shaped Peptoids [PDF]
BiomimeticsDeveloping safe and efficient cryoprotectants is critical for effective cryopreservation in biomedical applications. Inspired by natural antifreeze proteins (AFPs), a series of linear and star-shaped peptoids featuring isopropanol side chains to mimic ...
Lei Feng +7 more
doaj +2 more sources
Identification of cannabinoid-sensitive and -resistant oral bacteria [PDF]
Frontiers in MicrobiologyMarijuana, an emerging risk factor for periodontitis, contains multiple potent antibacterials, particularly the phytocannabinoids. Microbial dysbiosis is a hallmark of this destructive oral disease. We examined a panel of oral bacteria for susceptibility
David A. Scott +8 more
doaj +2 more sources
Membrane‐acting biomimetic peptoids against visceral leishmaniasis [PDF]
FEBS Open Bio, 2023 Visceral leishmaniasis (VL) is among the most neglected tropical diseases in the world. Drug cell permeability is essential for killing the intracellular residing parasites responsible for VL, making cell‐permeating peptides a logical choice to address ...
Vivek Kumar +8 more
doaj +3 more sources
One-Pot Approach Towards Peptoids Synthesis Using 1,4-Dithiane-2,5-Diol via Multicomponent Approach and DFT-Based Computational Analysis [PDF]
MoleculesPeptoids are peptidomimetics in which the side chain is attached to the nitrogen of the amide group rather than the α-carbon. This alteration in the backbone structure is highly valued because it endows beneficial properties, including enhanced ...
Musrat Shaheen, Akbar Ali
doaj +2 more sources
Advanced Science, 2020 Silicone (Si) is one type of anode materials with intriguingly high theoretical capacity. However, the severe volume change associated with the repeated lithiation and delithiation processes hampers the mechanical/electrical integrity of Si anodes and ...
Chaofeng Zhang +2 more
exaly +2 more sources
Assembled peptoid crystalline nanomaterials as carbonic anhydrase mimics for promoted hydration and sequestration of CO2 [PDF]
Nature CommunicationsCarbonic anhydrase (CA) mimics have received significant attention due to their promising applications in the enhanced hydration and sequestration of CO2.
Progyateg Chakma +12 more
doaj +2 more sources
Data-Driven Engineering of Thermostable Collagen-Mimetic Peptoid Triple Helices. [PDF]
Macromol Rapid CommunData‐driven active learning discovery of collagen‐mimetic peptoids capable of forming a thermostable collagen‐like triple helix using computational screening followed by experimental validation. ABSTRACT Collagen‐mimetic peptides (CMPs) are engineered molecules designed to replicate the triple‐helical structure of natural collagen.
Berlaga A +6 more
europepmc +2 more sources