Results 31 to 40 of about 2,770 (210)

Peptoids for biomaterials science [PDF]

open access: yesBiomater. Sci., 2014
Reports of peptoid structures and interfaces highlighting their potential as synthetically convenient, multifunctional, modular and precisely tunable biomaterials are reviewed.
openaire   +4 more sources

Antifouling Glycocalyx-Mimetic Peptoids [PDF]

open access: yesJournal of the American Chemical Society, 2013
The glycocalyx of the cell is composed of highly hydrated saccharidic groups conjugated to protein and lipid cores. Although components of the glycocalyx are important in cell-cell interactions and other specific biological recognition events, a fundamental role of the glycocalyx is the inhibition of nonspecific interactions at the cell surface ...
Ham, Hyun Ok   +4 more
openaire   +4 more sources

Microwave-Assisted Solid-Phase Synthesis of Peptoids [PDF]

open access: yes, 2016
Microwave irradiation reduces the reaction time for the solid-phase synthesis of peptoids. Under these conditions, coupling of each residue requires only 1 min. The purity and yields of peptoids synthesized in this way are as good as or better than those
Prasanna G. Alluri (2680135)   +4 more
core   +1 more source

Controlled synthesis of highly-branched plasmonic gold nanoparticles through peptoid engineering

open access: yesNature Communications, 2018
Peptoids are promising crystallization agents, as they offer the molecular recognition capabilities of proteins and peptides but with higher stability and synthetic tunability.
Feng Yan   +10 more
doaj   +1 more source

Antifouling Peptoid Biointerfaces

open access: yes, 2020
Recent advances in synthetic chemistry has led to the increasingly sophisticated design and preparation of biofunctional polymeric surfaces and materials. In this regard, synthetic poly-(N-substituted glycine) “peptoids” which mimic the structure and function of peptides play an important role, since they may attain functionalities similar to natural ...
Saxena, Varun   +2 more
openaire   +2 more sources

Cyclic β-Peptoids

open access: yesOrganic Letters, 2008
The first synthesis of functionalized -peptoid macrocycles is reported. X-ray crystallographic structure of tetramer 9 reveals a C2-symmetrical derivative with unexpected all-cis-amide bonds and spatial disposition of the appendages toward the two opposite faces of the ring. Quantum calculations suggest that 9 is locked in this layout.
Roy, Olivier   +4 more
openaire   +2 more sources

Effect of capping groups at the N- and C-termini on the conformational preference of α,β-peptoids [PDF]

open access: yes, 2012
invitation, special theme issue on Foldamer ChemistryInternational ...
Hjelmgaard, Thomas   +20 more
core   +1 more source

Photolithographic Synthesis of Peptoids [PDF]

open access: yes, 2016
We describe a novel photolithographic approach to the synthesis of peptoids (oligo-N-substituted glycines). This strategy enables the construction of a spatially addressable peptoid microarray, thus providing a potentially powerful tool for the discovery
Kevin J. Luebke (633497)   +6 more
core   +1 more source

Semaphorin 3A—Glycosaminoglycans Interaction as Therapeutic Target for Axonal Regeneration

open access: yesPharmaceuticals, 2021
Semaphorin 3A (Sema3A) is a cell-secreted protein that participates in the axonal guidance pathways. Sema3A acts as a canonical repulsive axon guidance molecule, inhibiting CNS regenerative axonal growth and propagation.
Yolanda Pérez   +7 more
doaj   +1 more source

A Systematic Review of Antiamyloidogenic and Metal-Chelating Peptoids: Two Structural Motifs for the Treatment of Alzheimer’s Disease

open access: yesMolecules, 2018
Alzheimer’s disease (AD) is an incurable form of dementia affecting millions of people worldwide and costing billions of dollars in health care-related payments, making the discovery of a cure a top health, societal, and economic priority.
Sherri C. Young
doaj   +1 more source

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