Results 51 to 60 of about 2,770 (210)
Macrocyclic Tetramers—Structural Investigation of Peptide-Peptoid Hybrids
Molecules, 2021 Outstanding affinity and specificity are the main characteristics of peptides, rendering them interesting compounds for basic and medicinal research. However, their biological applicability is limited due to fast proteolytic degradation.
Claudine Nicole Herlan +7 more
doaj +1 more source
Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source
Design and Synthesis of Novel Antibacterial Peptoids [PDF]
One of the current global challenges is tackling antibacterial multidrug resistance. The defense mechanisms of pathogenic bacteria and biofilm formation have significantly reduced the efficacy of conventional antibiotics.
Bahatheg, Ghayah
core +1 more source
Structural Diversity of Peptoids: Tube-Like Structures of Macrocycles
Molecules, 2020 Peptoids, or poly-N-substituted glycines, are characterised by broad structural diversity. Compared to peptides, they are less restricted in rotation and lack backbone-derived H bonding.
Claudine Nicole Herlan +4 more
doaj +1 more source
A Convenient Strategy to Access Diverse Libraries of Amphiphilic Compounds Based on Glycopeptoids
Chirality, Volume 38, Issue 7, July 2026.A synthetic platform based on a convergent synthetic strategy enables rapid access to a diverse amphiphilic glycopeptoids library. These modular systems exhibit self‐assembly into nanoscale aggregates, highlighting their potential as customizable platforms for drug delivery, biomimetic materials, and membrane protein stabilization.
Ludovica Dei +9 more
wiley +1 more source
Sequence-defined peptoids <i>via</i> iterative exponential growth. [PDF]
Chem SciSynthetic control over polymer sequence, composition, and stereochemistry is critical to understanding their influence on the intramolecular and intermolecular interactions of polymers.
Clapperton AM, Hood C, Tran H.
europepmc +3 more sources
Engineering Stealth Properties of Fluorescent Polymeric Nanoparticles by Short‐Chain Polysarcosine
Aggregate, Volume 7, Issue 6, June 2026.To define the minimal polysarcosine chain length required for nanoparticle stealth properties, we engineered dye‐loaded polymeric nanoparticles functionalized with 5‐, 11‐, or 19‐mer peptoids. Only nanoparticles with 19‐mer polysarcosine achieved near‐neutral zeta potential, suppressed nonspecific interactions with glass surface and live cells ...
Tanushree Gupta +9 more
wiley +1 more source
Alkoxide-Mediated Truncation of Peptoids [PDF]
, 2017 펩토이드는 펩타이드를 모방하도록 고안된 작은 단백질 유사 사슬 종류 중의 하나이다.(Peptidomimetic) 펩타이드와 달리 아마이드 결합 을 가지지 않아 가수분해에 자유롭고 셀 투과성이 높으며 다양한 조건 에서 안정성이 뛰어난 특성을 지니고 있다. 이와 같은 다양한 장점으로 인하여 차세대 화학 및 생물분야에 여러모로 유용하게 활용될 수 있는 물질로 주목받고 있다. 이 논문은 염기성 조건에서 특이적으로 선형과 고리형 펩토이드가 절단되는 현상에
현주영
core
Journal of Biomedical Materials Research Part A, Volume 114, Issue 6, June 2026.ABSTRACT Burn wounds present significant clinical challenges due to high infection risk, delayed healing, and extensive tissue damage. The development of biomimetic skin substitutes capable of simultaneously supporting tissue regeneration and preventing infection remains a critical need in burn wound management. In this study, a novel ceragenin (CSA‐44)
Nawal Aljayyousi +9 more
wiley +1 more source
Solid-Phase Insertion of N-mercaptoalkylglycine Residues into Peptides
Molecules, 2019 N-mercaptoalkylglycine residues were inserted into peptides by reacting N-free amino groups of peptides, which were initially synthesized on 2-chlorotrityl resin (Cltr) using the Fmoc/tBu method, with bromoacetic acid and subsequent nucleophilic ...
Spyridon Mourtas +2 more
doaj +1 more source