Results 61 to 70 of about 2,770 (210)
A Peptoid Ribbon Secondary Structure [PDF]
Angewandte Chemie International Edition, 2013 foldamers that have been shown to possess numerous biological functions and could find use in a range of fundamental and applied contexts as bio-inspired materials. Peptoids are highly attractive scaffolds for such purposes, as their non-native backbones are resistant to proteolytic degradation and their straightforward, modular synthesis enables the ...
J Aaron, Crapster +2 more
openaire +2 more sources
Antimicrobial Peptoids Are Effective against Pseudomonas aeruginosa Biofilms [PDF]
, 2011 The resistance of biofilms to conventional antibiotics complicates the treatment of chronic cystic fibrosis (CF). We investigated the effects of peptoids, peptides, and conventional antibiotics on the biomass and cell viability within ...
Ann M. Czyzewski +5 more
core +1 more source
Small StructuresControlling chromophore chirality in three‐dimensional space is crucial for understanding the structure–chiroptical relationship. Such control enables the prediction of ideal materials for use in chiral photonic applications.
Jinyoung Oh +7 more
doaj +1 more source
Promising Antibiofilm Activity of Peptidomimetics
Frontiers in Microbiology, 2018 Pathogenic biofilms are a global health care concern, as they can cause extensive antibiotic resistance, morbidity, mortality, and thereby substantial economic loss.
Rafael Gomes Von Borowski +4 more
doaj +1 more source
Surface-immobilised antimicrobial peptoids [PDF]
Biofouling, 2008 Surface modification techniques that create surfaces capable of killing adherent bacteria are promising solutions to infections associated with implantable medical devices. Antimicrobial (AM) peptoid oligomers (ampetoids) that were designed to mimic helical AM peptides were synthesised with a peptoid spacer chain to allow mobility and an adhesive ...
Andrea R, Statz +4 more
openaire +2 more sources
On the Conformation of Anionic Peptoids in the Gas Phase
Biomacromolecules, 2022 Although N-(S)-phenylethyl peptoids are known to adopt helical structures in solutions, the corresponding positively charged ions lose their helical structure during the transfer from the solution to the gas phase due to the so-called charge solvation effect.
Weber, Perrine +6 more
openaire +3 more sources
A Rapid and Efficient Building Block Approach for Click Cyclization of Peptoids
Frontiers in Chemistry, 2020 Cyclic peptide-peptoid hybrids possess improved stability and selectivity over linear peptides and are thus better drug candidates. However, their synthesis is far from trivial and is usually difficult to automate.
Mamidi Samarasimhareddy +5 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2022 The synthesis and conformational analysis of the first series of peptoid oligomers composed of consecutive N-(alkylamino)glycine units is investigated. We demonstrate that N-(methylamino)glycine homooligomers can be readily synthesized in solution using ...
Maxime Pypec +3 more
doaj +1 more source
Applying a Hydrophilic Modified Hollow Fiber Membrane to Reduce Fouling in Artificial Lungs
Separations, 2021 Membranes for use in high gas exchange lung applications are riddled with fouling. The goal of this research is to create a membrane that can function in an artificial lung until the actual lung becomes available for the patient.
Nawaf Alshammari +2 more
doaj +1 more source
Role of Histidine‐Containing Peptoids in Accelerating the Kinetics of Calcite Growth
Advanced Functional Materials, Volume 36, Issue 34, 27 April 2026.Amphiphilic histidine‐containing peptoids mimic carbonic anhydrase (CA) to accelerate calcite step growth. In the presence of Zn2+, they promote the deprotonation of HCO3−, the desolvation of Ca2+, and the reorganization of interfacial hydration layers, thereby reducing the activation barrier for calcite growth.
Mingyi Zhang +5 more
wiley +1 more source