Results 81 to 90 of about 2,770 (210)
Synthesis of potential antimicrobial peptide mimetics, peptoids [PDF]
, 2019 During the last 10years, natural macrocyclic peptides have been tested as antimicrobial drugs against E.Coli, ect, with positive results. Because peptides are naturally occurring, infectious diseases are prone to become resistant to them the same way ...
Dokkedal, Sandra Abildgaard +2 more
core
Advanced Sensor Research, Volume 5, Issue 3, March 2026.ABSTRACT Profluorescent nitroxides (PFNs) have established themselves as powerful tools for monitoring oxidative processes and subcellular redox dynamics by reactive oxygen species (ROS). Their characteristic “off–on” behavior arises from the efficient, proximity‐driven quenching of covalently bound fluorophores by paramagnetic nitroxide radicals ...
Haider N. Sultani +4 more
wiley +1 more source
DNA-Encoded Combinatorial Library of Macrocyclic Peptoids [PDF]
, 2019 We report the design and synthesis of a DNA-encoded one-bead one-compound library of cyclic peptoids composed of more than 11 million molecules. We show that affinity-based screening of this large library can identify cyclic peptoid ligands for a target ...
Min Hyeon Shin (1466161) +2 more
core +1 more source
Molecules, 2007 Two new groups of cholane-peptoid hybrid macrocycles were produced by implementing novel combinations of the MiB methodology. Steroid-based hybrid macrolactams including heterocycle and aryl moieties were obtained by utilizing cholanic dicarboxylic acids
Ludger A. Wessjohann, Daniel G. Rivera
doaj +1 more source
Advanced Science, Volume 13, Issue 18, 27 March 2026.A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding +5 more
wiley +1 more source
Derivatization of Peptoids Using Chan-Lam Reaction [PDF]
, 2018 Peptides are representative biomolecules that possess various physiological activities in vivo. Thus, they are attractive chemical tools for chemical biology and drug development.
송지현
core
N-[2-(Cyclohexylamino)-2-oxoethyl]-N-(4-octyloxy)phenyl-prop-2-enamide
Molbank, 2016 N-[2-(Cyclohexylamino)-2-oxoethyl]-N-(4-octyloxy)phenyl-prop-2-enamide was prepared in good yield by coupling of 4(octyloxy)aniline, Cyclohexyl isocyanide, paraformaldehyde and acrylic acid by multicomponent Ugi reaction, at room temperature.
Shimoga D. Ganesh +3 more
doaj +1 more source
Protein Structure Determination by Racemic and Quasi‐Racemic X‐Ray Crystallography
ChemBioChem, Volume 27, Issue 4, 25 February 2026.Racemic mixtures of protein enantiomers facilitate formation of diffraction‐quality crystals in centrosymmetric space groups that have quantized phases which simplify structure solution. Quasi‐racemic mixtures of a protein and its mirror image isomorph similarly facilitate formation of highly ordered crystals.
Stephen B. H. Kent
wiley +1 more source
Peptoids and methods for attenuating inflammatory response [PDF]
, 2021 Disclosed herein are peptoids and methods for attenuating inflammatory responses, and more particularly RAGE-associated inflammatory ...
Wolf, Lauren +2 more
core +1 more source
Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs
Molecules, 2017 The rapid emergence of multidrug-resistant pathogens has evolved into a global health problem as current treatment options are failing for infections caused by pan-resistant bacteria.
Natalia Molchanova +2 more
doaj +1 more source