Results 91 to 100 of about 2,770 (210)
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang +7 more
wiley +1 more source
Synthesis and Mass Spectrometry Analysis of Oligo-Peptoids [PDF]
Peptoids are sequence-controlled peptide-mimicking oligomers consisting of N-alkylated glycine units. Among many potential applications, peptoids have been thought of as a type of molecular information storage.
Browne, Michael D. +7 more
core +1 more source
Synthesis and Characterization of Glyco‐Decorated Silsesquioxane‐Metallosalen Complexes
Glyco‐decorated COSS‐metallosalen complexes were synthesized and characterized. Their metal ion‐dependent D4h or S4 geometry was experimentally verified by single‐crystal X‐ray diffraction using model compounds with the same tetranuclear core. Ribonuclease activity of these complexes was studied, but it remained modest compared to other metal ion‐based
Hanni Haapsaari +4 more
wiley +1 more source
Programmed assembly of nanoscale structures using peptoids. [PDF]
Sequence-specific polymers are the basis of the most promising approaches to bottom-up programmed assembly of nanoscale materials. Examples include artificial peptides and nucleic acids.
Ren, Jianhua (University of the Pacific, Stockton, CA) +7 more
core +1 more source
Cis–Trans Amide Bond Rotamers in β‑Peptoids and Peptoids: Evaluation of Stereoelectronic Effects in Backbone and Side Chains [PDF]
Non-natural peptide analogs have significant potential for the development of new materials and pharmacologically active ligands. One such architecture, the β-peptoids (N-alkyl-β-alanines), has found use in a variety of biologically active compounds but ...
Christian A. Olsen (135397) +4 more
core +3 more sources
Liquid–Liquid Phase Separation in Major Hallmarks of Cancer
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie +10 more
wiley +1 more source
Ethyl({[acryloyl(furan-2-ylmethyl)amino]acetyl}amino)acetate
Ethyl({[acryloyl(furan-2-ylmethyl)amino]acetyl}amino)acetate was synthesized via Ugi four component (4C) reaction at ambient temperature. The protocol employs a reaction between formaldehyde, furfurylamine, acrylic acid, and ethyl 2-isocyanoacetate.
Shimoga D. Ganesh +3 more
doaj +1 more source
The Immunogenicity of Peptoid-Protein Conjugates
We demonstrate that a peptoid composed of five monomers and attached via a maleimide linker to a carrier protein elicits anti-peptoid, anti-linker and anti-carrier antibodies in rabbits. Specific anti-peptoid antibodies were affinity purified and used to reproducibly retrieve three specific peptoid-coupled beads from 20,000 irrelevant peptoid-beads ...
Case, Allison +11 more
openaire +2 more sources
Quantitative Evaluation of the Relative Cell Permeability of Peptoids and Peptides [PDF]
We evaluated quantitatively the relative cell permeability of peptoids and peptides using a cell-based reporter gene-based assay. Generally, peptoids were much more cell permeable than the corresponding peptides, though the difference decreased with ...
Yong-Uk Kwon (1635325) +1 more
core +1 more source

