Results 101 to 110 of about 2,770 (210)

Antimicrobial Peptoids: Design, Synthesis and Biological Applications [PDF]

open access: yes, 2016
The emergence of antimicrobial resistance is a severe threat to global health and new classes of antibiotics are desperately needed. Peptoids, or oligo-N-substituted glycines, are a group of peptidomimetics with increased structural stability and ...
BOLT, HANNAH,LOUISE
core  

Structure and Activity of Antimicrobial Peptoids [PDF]

open access: yes, 2020
This thesis concerns complementary experimental and computational investigations into the relationship between the primary sequence and secondary structure of peptoids.
WOODHOUSE, VANESSA,JANE
core  

Facile Solid-Phase Parallel Synthesis of Linear and Cyclic Peptoids for Comparative Studies of Biological Activity [PDF]

open access: yes, 2016
A series of linear and cyclic peptoids, which were expected to possess better pharmacokinetic properties and biological activities for blocking the interaction between apolipoprotein E and amyloid-β, were designed and synthesized as possible therapeutic ...
Yong-Uk Kwon (1635325)   +1 more
core   +1 more source

Synthesis of functionalized peptoids designed to coordinate to quantum dots for use in biomedical applications [PDF]

open access: yes, 2021
Quantum dots are a potential replacement for traditional organic fluorophores. The dots’ inherent toxicity is the main barrier limiting biomedical applications, but designed peptoids could provide a solution for this.
Maddux, Cameron
core   +1 more source

Ring-Opening of Acetylated Cyclic Peptoids under Acidic Conditions [PDF]

open access: yes, 2017
Cyclic peptidomimetics have been considered as attractive molecular probes in drug discovery and chemical biology. Compared to linear peptoids, cyclic peptoids possess increased conformational rigidity and relatively pre-organized structures, and thus ...
박현정
core  

peptoid

open access: yes
Citation: 'peptoid' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12703 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Dimeric peptoids as antibacterial agents

open access: yesBioorganic Chemistry
Building upon our previous study on peptoid-based antibacterials which showed good activity against Gram-positive bacteria only, herein we report the synthesis of 34 dimeric peptoid compounds and the investigation of their activity against Gram-positive and Gram-negative pathogens.
Ghayah, Bahatheg   +8 more
openaire   +2 more sources

The activity of antimicrobial peptoids against multidrug-resistant ocular pathogens [PDF]

open access: yes
Background: Ocular infections caused by antibiotic-resistant pathogens can result in partial or complete vision loss. The development of pan-resistant microbial strains poses a significant challenge for clinicians as there are limited antimicrobial ...
Hui, Alex   +16 more
core   +1 more source

Peptoides macrocycliques photosensibles pour le stockage de l'énergie solaire [PDF]

open access: yes
editorial reviewedIn the context of rising global energy consumption and dwindling fossil fuel reserves, the shift towards renewable energy sources has become essential. Solar energy stands out as particularly promising due to its abundance.
Duez, Quentin   +6 more
core  

Peptoids and methods for treating Alzheimer\u27s disease [PDF]

open access: yes, 2019
Provided herein are peptoids capable of inhibiting or reversing amyloid .beta. (A.beta.) fibril or plaque production. The peptoids form a helical structure with three monomers per helical turn and have at least four monomers with a side-chain having an ...
Moss, Melissa   +2 more
core   +1 more source

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