Results 21 to 30 of about 2,770 (210)
Frontiers in Bioscience-Landmark, 2022 Background: Antimicrobial peptides (AMPs) are short, cationic, amphipathic molecules that have gained tremendous popularity as alternatives to traditional antibiotics due to their lower propensity to develop bacterial resistance.
Bettina Simone Fleck +4 more
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Advanced Science, 2023 Antimicrobial peptides (AMPs) are promising therapeutics in the fight against multidrug‐resistant bacteria. As a mimic of AMPs, peptoids with N‐substituted glycine backbone have been utilized for antimicrobials with resistance against proteolytic ...
Minsang Kim +12 more
doaj +1 more source
Reconciling Simulations and Experiments With BICePs: A Review
Frontiers in Molecular Biosciences, 2021 Bayesian Inference of Conformational Populations (BICePs) is an algorithm developed to reconcile simulated ensembles with sparse experimental measurements.
Vincent A. Voelz +2 more
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Solid-Phase Synthesis of N-Substituted Glycine Oligomers (α‑Peptoids) and Derivatives
Molecules, 2010 Peptoids (N-substituted polyglycines and extended peptoids with variant backbone amino-acid monomer units) are oligomeric synthetic polymers that are becoming a valuable molecular tool in the biosciences.
Rodney J. Ouellette, Adrian S. Culf
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On-Resin Click-Glycoconjugation of Peptoids [PDF]
, 2009 Norgren AS, Budke C, Majer Z, Heggemann C, Koop T, Sewald N. On-Resin Click-Glycoconjugation of Peptoids. SYNTHESIS. 2009;2009(03):488-494.Peptoids are unnatural peptide-like oligomers having the side-chain attached to the glycine nitrogen.
Norgren, Anna S. +5 more
core +1 more source
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity.
PLoS ONE, 2014 Cationic, amphipathic host defense peptides represent a promising group of agents to be developed for anticancer applications. Poly-N-substituted glycines, or peptoids, are a class of biostable, peptidomimetic scaffold that can display a great diversity ...
Wei Huang +6 more
doaj +1 more source
Synthesis of Biaryl-Linked Cyclic Peptoids [PDF]
, 2017 Peptoids, a class of peptidomimetic, have gained considerable attention as potential therapeutic agents due to properties such as biocompatibility and resistance to enzymatic degradation.
Webster, Alexandra M., Cobb, Steven L.
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Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids
Pharmaceuticals, 2021 Viral infections, such as those caused by Herpes Simplex Virus-1 (HSV-1) and SARS-CoV-2, affect millions of people each year. However, there are few antiviral drugs that can effectively treat these infections.
Gill Diamond +11 more
doaj +1 more source
Design, Synthesis, and Characterization of Heparin-Binding Peptoids [PDF]
, 2016 A series of N-substituted glycine oligomers (peptoids) of varying length and side chains was synthesized with the aim of producing peptidomimetics that would bind with high affinity to heparin and thereby neutralize its anticoagulant activity.
Bruce Kevin Ford (1954084) +2 more
core +1 more source
Antioxidants, 2023 Copper is an essential metal ion that is involved in critical cellular processes, but which can also exhibit toxic effects through its ability to catalyze reactive oxygen species (ROS) formation. Dysregulation of copper homeostasis has been implicated in
Anastasia Esther Behar, Galia Maayan
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