Results 71 to 80 of about 5,562 (217)
Advanced Sensor Research, Volume 5, Issue 3, March 2026.ABSTRACT Profluorescent nitroxides (PFNs) have established themselves as powerful tools for monitoring oxidative processes and subcellular redox dynamics by reactive oxygen species (ROS). Their characteristic “off–on” behavior arises from the efficient, proximity‐driven quenching of covalently bound fluorophores by paramagnetic nitroxide radicals ...
Haider N. Sultani +4 more
wiley +1 more source
Self-assembly of ultra-small micelles from amphiphilic lipopeptoids [PDF]
, 2017 Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca.
Aida +37 more
core +1 more source
Advanced Science, Volume 13, Issue 18, 27 March 2026.A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding +5 more
wiley +1 more source
A readily applicable strategy to convert peptides to peptoid-based therapeutics. [PDF]
PLoS ONE, 2013 Incorporation of unnatural amino acids and peptidomimetic residues into therapeutic peptides is highly efficacious and commonly employed, but generally requires laborious trial-and-error approaches.
Minyoung Park +3 more
doaj +1 more source
Protein Structure Determination by Racemic and Quasi‐Racemic X‐Ray Crystallography
ChemBioChem, Volume 27, Issue 4, 25 February 2026.Racemic mixtures of protein enantiomers facilitate formation of diffraction‐quality crystals in centrosymmetric space groups that have quantized phases which simplify structure solution. Quasi‐racemic mixtures of a protein and its mirror image isomorph similarly facilitate formation of highly ordered crystals.
Stephen B. H. Kent
wiley +1 more source
Non-natural protein mimetics for the treatment of Alzheimer\u27s disease [PDF]
, 2011 Alzheimer\u27s disease (AD) is a slow degenerative disease that causes memory loss and eventually leads to death. AD is caused by the aggregation of the amyloid-beta protein, found on the outside of brain cells; once the amyloid-beta protein begins to ...
Brown, Jasmine +4 more
core +1 more source
Proteasome Inhibitors: Harnessing Proteostasis to Combat Disease [PDF]
, 2020 The proteasome is the central component of the main cellular protein degradation pathway. During the past four decades, the critical function of the proteasome in numerous physiological processes has been revealed, and proteasome activity has been linked
Li, Jing, Sherman, David J.
core
A Modular Class of Fluorescent Difluoroboranes: Synthesis, Structure, Optical Properties, Theoretical Calculations and Applications for Biological Imaging. [PDF]
, 2016 Ten borylated bipyridines (BOBIPYs) have been synthesized and selected structural modifications have been made that allow useful structure-optical property relationships to be gathered.
Auvinet +34 more
core +1 more source
Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang +7 more
wiley +1 more source
Protein Isolation Using Peptoid Based Affinity Chromatography [PDF]
, 2013 Protein purification is essential for advancements in biotechnology. There are several different methods employed in purifying a particular protein from a complex sample such as a cell lysate.
Dunn, Megan
core +1 more source