Results 71 to 80 of about 3,952 (212)
Antiviral Effect of Antimicrobial Peptoid TM9 and Murine Model of Respiratory Coronavirus Infection
New antiviral agents are essential to improving treatment and control of SARS-CoV-2 infections that can lead to the disease COVID-19. Antimicrobial peptoids are sequence-specific oligo-N-substituted glycine peptidomimetics that emulate the structure and ...
Maxim Lebedev +8 more
doaj +1 more source
Breaking Physiological Barriers in Women's Health: Mucoadhesive and Stimuli‐Responsive Nanomaterials
Drug delivery vehicles generated from biomaterials for women's health. In particular, the breast and the reproductive system, including the ovary, uterus, cervix, vagina, and the surrounding tissues, targeted drug delivery. BioRender. ABSTRACT Biomaterials are natural or synthetic molecules that exhibit biocompatibility, biodegradability, or ...
Maddox Parsons +4 more
wiley +1 more source
Functionalized Surface Coatings for Rigid Contact Lenses
This research evolves into a comparative study of three different phenolic composites as coatings for rigid contact lenses, with a particular emphasis on enhancing their antifouling properties and hydrophobicity.
Roeya Refaei +8 more
doaj +1 more source
Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang +11 more
wiley +1 more source
We describe the synthesis and characterization of the first generation of oligomers consisting of alternating repeats of α-amino acids and chiral N-alkyl-β-alanine (β-peptoid) residues.
Matthias Witt (1294776) +6 more
core +2 more sources
Measurement of Peptoid Concentration Using UV Spectroscopy [PDF]
The goal of this research is to establish a relationship between ultraviolet adsorption and peptiod concentration to be used to determine the concentration of an unknown peptoid sample.
Holland, Katie
core +3 more sources
Cellular delivery using peptoid carriers [PDF]
Efficient delivery into cells is essential for many applications. However, cellular access of “cell-impermeable” molecules, such as drugs, sensors, proteins and oligonucleotides, can often be severely limited due to the plasma membrane which protects ...
Escher, Geraldine
core
Learning from host-defense peptides: cationic, amphipathic peptoids with potent anticancer activity.
Cationic, amphipathic host defense peptides represent a promising group of agents to be developed for anticancer applications. Poly-N-substituted glycines, or peptoids, are a class of biostable, peptidomimetic scaffold that can display a great diversity ...
Wei Huang +6 more
doaj +1 more source
Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer
Small molecules and peptide inhibitors have their benefits and faults when it comes to inhibiting protein-protein interactions. Here, the authors designed a peptoid-peptide hybrid that inhibited β-catenin/TCF interactions, leading to inhibition of Wnt ...
Jeffrey A. Schneider +12 more
doaj +1 more source

