Results 81 to 90 of about 5,562 (217)
Bioactivity-guided mass spectral net working reveals a new set of allbicidin derivatives from Xanthomonas albilineans [PDF]
, 2016 Albicidin is produced by the sugarcane pathogenic bacterium Xanthomonas albilineans and is a potent antibiotic specifically targeting the bacterial DNA gyrase with an IC50 value in the nanomolar range.
Cociancich, Stéphane +6 more
core +1 more source
Synthesis and Characterization of Glyco‐Decorated Silsesquioxane‐Metallosalen Complexes
ChemistrySelect, Volume 11, Issue 5, 5 February 2026.Glyco‐decorated COSS‐metallosalen complexes were synthesized and characterized. Their metal ion‐dependent D4h or S4 geometry was experimentally verified by single‐crystal X‐ray diffraction using model compounds with the same tetranuclear core. Ribonuclease activity of these complexes was studied, but it remained modest compared to other metal ion‐based
Hanni Haapsaari +4 more
wiley +1 more source
100th Anniversary of Macromolecular Science Viewpoint: Opportunities in the Physics of Sequence-Defined Polymers [PDF]
, 2020 Polymer science has been driven by ever-increasing molecular complexity, as polymer synthesis expands an already-vast palette of chemical and architectural parameter space.
Perry, Sarah L., Sing, Charles E.
core +3 more sources
Scientific Reports, 2017 Inheritance of the apolipoprotein E4 (apoE4) genotype has been identified as the major genetic risk factor for late onset Alzheimer’s disease (AD). Studies have shown that apoE, apoE4 in particular, binds to amyloid-β (Aβ) peptides at residues 12-28 of ...
Shan Liu +12 more
doaj +1 more source
Liquid–Liquid Phase Separation in Major Hallmarks of Cancer
Cell Proliferation, Volume 59, Issue 2, February 2026.Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie +10 more
wiley +1 more source
Formation of Molecularly Imprinted Polymer Matrices using [PDF]
, 2012 This study serves as a proof of concept that a poly(acrylonitrile-co-acrylic acid) may be used to form an chiral selective polymer membrane for discrimination of L-tryptophan from racemic tryptophan.
Erwin, William
core +1 more source
An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide
Advanced Materials, Volume 38, Issue 4, 16 January 2026.Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon +5 more
wiley +1 more source
Rapid Quantification of Molecular Diversity for Selective Database Acquisition [PDF]
, 1997 There is an increasing need to expand the structural diversity of the molecules investigated in lead-discovery programs. One way in which this can be achieved is by acquiring external datasets that will enhance an existing database.
Ash J. E. +19 more
core +1 more source
Antiviral Effect of Antimicrobial Peptoid TM9 and Murine Model of Respiratory Coronavirus Infection
PharmaceuticsNew antiviral agents are essential to improving treatment and control of SARS-CoV-2 infections that can lead to the disease COVID-19. Antimicrobial peptoids are sequence-specific oligo-N-substituted glycine peptidomimetics that emulate the structure and ...
Maxim Lebedev +8 more
doaj +1 more source
Thermoresponsive poly(2-oxazoline)s, polypeptoids, and polypeptides [PDF]
, 2017 This review covers the recent advances in the emerging field of thermoresponsive polyamides or polymeric amides, i.e., poly(2-oxazoline)s, polypeptoids, and polypeptides, with a specific focus on structure-thermoresponsive property relationships, self ...
Hoogenboom, Richard, Schlaad, Helmut
core +2 more sources