Results 101 to 110 of about 3,952 (212)

Submonomer Synthesis of A Hybrid Peptoid–Azapeptoid Library

, 2016
We recently reported efficient conditions for the synthesis of N-azapeptoid libraries via the typical submonomer strategy of peptoid synthesis but that substitutes N-acyl hydrazides for primary amines as submonomers.
Bani Kanta Sarma (2037217), Thomas Kodadek (61725)   +1 more
core   +1 more source

Peptoid-based macrodiscs of variable lipid composition for structural studies of membrane proteins by oriented-sample solid-state NMR

Journal of Structural Biology: X
Solid-state Nuclear Magnetic Resonance (NMR) in combination with magnetically aligned discoidal lipid mimics allows for studying the conformations of membrane proteins in planar, lipid-rich bilayer environments and at the physiological temperature.
Azamat R. Galiakhmetov, Adit A. Shah, Addison Lane, Carolynn M. Davern, Caroline Proulx, Alexander A. Nevzorov   +5 more
doaj   +1 more source

Novel Peptoid Building Blocks: Synthesis of Functionalized Aromatic Helix-Inducing Submonomers

, 2016
Peptoids, oligo-N-substituted glycines, can fold into well-defined helical secondary structures. The design and synthesis of new peptoid building blocks that are capable of both (a) inducing a helical secondary structure and (b) decorating the helices ...
Annelise E. Barron (393021), Ronald N. Zuckermann (233847), Jiwon Seo (528884)   +2 more
core   +1 more source

Solution effects on the self‐association of a water‐soluble peptoid

, 2019
A desire to replicate the structural and functional complexity of proteins with structured, sequence‐specific oligomers motivates study of the structural features of water‐soluble peptoids (N ‐substituted glycine oligomers).
Kyra N. McComas, Jimenez, Christian J., Samuel Hough, Hough, Samuel, Fuller, Amelia A., Huber, Jonathan, Kunkel, Jeffrey, Prashanth Asuri, Christian J. Jimenez, Alberto Ortega, Dowell, Kalli M., Asuri, Prashanth, McComas, Kyra N., Ortega, Alberto, Amelia A. Fuller, Jeffrey Kunkel, Jonathan Huber, Kalli M. Dowell   +17 more
core   +1 more source

Preparation of N‑Substituted N‑Arylsulfonylglycines and Their Use in Peptoid Synthesis

, 2015
To increase the chemical diversity accessible with peptoids and peptide–peptoid hybrids, N-alkylated arylsulfonamides were used to prepare side chain protected N-substituted glycines compatible with solid-phase synthesis.
Steve Jobin (1479214), Antoine Derson (1479220), Eric Biron (1479226), Claire Herby (1479223), Simon Vézina-Dawod (1479217)   +4 more
core   +1 more source

Preparation of N-substituted N-arylsulfonylglycines and their use in peptoid synthesis

, 2015
To increase the chemical diversity accessible with peptoids and peptide–peptoid hybrids, N-alkylated arylsulfonamides were used to prepare side chain protected N-substituted glycines compatible with solid-phase synthesis.
Derson, Antoine, Biron, Éric, Jobin, Steve, Herby, Claire, Vézina-Dawod, Simon   +4 more
core   +1 more source

The Effect of Peptoid Monolayers on Functionalized Gold Nanoparticle Film Assembly at the Oil-Water Interface

, 2020
Gold nanoparticles (AuNPs) that are ordered in two-dimensional (2D) arrays have been shown to exhibit optoelectronic properties that make them useful in a variety of technologies, including sensors for pollutants.
Whitney, Elizabeth
core  

Crystallization-Induced Flower-like Superstructures via Peptoid Helix Assembly

We report a unique method to construct hierarchical superstructures based on molecular programming of peptidomimetics. Chiral steric hindrance in the polymer backbone stabilizes peptoid helices that crystallize into nanosheets during solvent evaporation.
Matthew Mecklenburg (1467652), M. Scott Shell (267372), Rachel A. Segalman (1302423), Kai-Chieh Yang (8891549), Ronnie V. Garcia (8879138), Niko W. Vlahakis (18255804), Daniela M. Rivera Mirabal (11973893), Shawn D. Mengel (17986292), Phong H. Nguyen (13004438), Craig J. Hawker (675327), Jose A. Rodriguez (1982692)   +10 more
core   +1 more source

Trifluoroacetylation and Sulfur Oxidation States Modulate Cis-Trans Isomerization and Atropisomerism in N-Aryl Peptoids. [PDF]

Chirality
Raju NKM, Paul B, Prajapati J, Chatterjee S, Kumar ESS, Dubey KD.   +5 more
europepmc   +1 more source

Recent progress in the structure-activity relationship of antibacterial peptoids. [PDF]

RSC Adv
Bahatheg G, Ibisanmi TA, Black DS, Willcox MDP, Kumar N.   +4 more
europepmc   +1 more source