Results 91 to 100 of about 3,952 (212)

Collagen-Like Triple Helices Incorporating Peptoid Residues^†

, 2016
Collagen-Like Triple Helices Incorporating Peptoid Residues†
Murray Goodman (2652340), Giuseppe Melacini (118426), Yangbo Feng (1346307)   +2 more
core   +1 more source

Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins

Scientific Reports, 2018
Acute lung injury (ALI) leads to progressive loss of breathing capacity and hypoxemia, as well as pulmonary surfactant dysfunction. ALI’s pathogenesis and management are complex, and it is a significant cause of morbidity and mortality worldwide ...
Ann M. Czyzewski, Lynda M. McCaig, Michelle T. Dohm, Lauren A. Broering, Li-Juan Yao, Nathan J. Brown, Maruti K. Didwania, Jennifer S. Lin, Jim F. Lewis, Ruud Veldhuizen, Annelise E. Barron   +10 more
doaj   +1 more source

Peptide to Peptoid Substitutions Increase Cell Permeability in Cyclic Hexapeptides

, 2016
The effect of peptide-to-peptoid substitutions on the passive membrane permeability of an N-methylated cyclic hexapeptide is examined. In general, substitutions maintained permeability but increased conformational heterogeneity.
Gilles Goetz (1670308), Michael J. Shapiro (508601), Bhagyashree Khunte (1399660), Joshua Schwochert (1670326), Ray F Berkeley (1670320), Rushia Turner (1670302), Kelsie M. Rodriguez (1670305), Alexandra R Ponkey (1670311), Amit S. Kalgutkar (1585282), Melissa Thang (1670317), Siegfried S F Leung (1670323), Chris Limberakis (1348395), Heather Eng (1670314), Matthew P. Jacobson (174588), David A. Price (36138), Alan M. Mathiowetz (1348374), R. Scott Lokey (133725), Spiros Liras (1585273)   +17 more
core   +1 more source

Engineering Stealth Properties of Fluorescent Polymeric Nanoparticles by Short‐Chain Polysarcosine

Aggregate
The stealth properties of nanoparticles (NPs) constitute key parameters controlling colloidal stability and nonspecific interactions, which are critical for biological applications.
Tanushree Gupta, Quynh Anh Bui, Horgan Manirakiza, Lina El Hajji, Remi Pelletier, Nicolas Humbert, Abdel Wahab Mouhamad, Andreas Reisch, Arnaud Gautier, Andrey S. Klymchenko   +9 more
doaj   +1 more source

Peptoid Interactions with Self-Assembled Gold Nanosheets

, 2020
Gold nanoparticles have the ability to self-assemble into two-dimensional sheet-like structures at air-liquid and liquid-liquid interfaces. These gold nanosheets, which are easy to detect based on their optical properties, have been used in applications ...
Zaczyk, Misty
core  

Short Alkylated Peptoid Mimics of Antimicrobial Lipopeptides

, 2011
We report the creation of alkylated poly- N -substituted glycine (peptoid) mimics of antimicrobial lipopeptides with alkyl tails ranging from 5 to 13 carbons.
Amy J. Karlsson, Tyler M. Miller, Sergei Vakulenko, Nathaniel P. Chongsiriwatana, Shahriar Mobashery, Sean P. Palecek, Modi Wetzler, Annelise E. Barron   +7 more
core   +1 more source

Implementing Efficient Peptoid‐Mediated Delivery of RNA‐Based Therapeutics to the Vocal Folds

Laryngoscope Investigative Otolaryngology, 2019
Objective We hypothesize that Smad3 is a master regulator of fibrosis in the vocal folds (VFs) and RNA‐based therapeutics targeting Smad3 hold therapeutic promise. Delivery remains challenging.
Shigeyuki Mukudai, Iv Kraja, Renjie Bing, Danielle M. Nalband, Mallika Tatikola, Nao Hiwatashi, Kent Kirshenbaum, Ryan C. Branski   +7 more
doaj   +1 more source

Chiral Display of Pyrenes on a Peptoid Backbone: Conformational Homogeneity of Peptoid Controls Excimer Chirality

Small Structures
Controlling chromophore chirality in three‐dimensional space is crucial for understanding the structure–chiroptical relationship. Such control enables the prediction of ideal materials for use in chiral photonic applications.
Jinyoung Oh, Yongmoon Lee, Gahee Noh, Dongcheol Park, Hohjai Lee, Junseong Lee, Changsoon Kim, Jiwon Seo   +7 more
doaj   +1 more source

Corrigendum: Recent Advances in the Application Peptide and Peptoid in Diagnosis Biomarkers of Alzheimer's Disease in Blood

Frontiers in Molecular Neuroscience, 2022
Yuxin Guo, Yuxin Guo, Zhiyuan Hu, Zhiyuan Hu, Zhiyuan Hu, Zhiyuan Hu, Zihua Wang   +6 more
doaj   +1 more source

Dimeric peptoids as antibacterial agents

Bioorganic Chemistry
Building upon our previous study on peptoid-based antibacterials which showed good activity against Gram-positive bacteria only, herein we report the synthesis of 34 dimeric peptoid compounds and the investigation of their activity against Gram-positive and Gram-negative pathogens.
Ghayah, Bahatheg, Rajesh, Kuppusamy, Muhammad, Yasir, Samara, Bridge, Shyam K, Mishra, Charles G, Cranfield, David, StC Black, Mark, Willcox, Naresh, Kumar   +8 more
openaire   +2 more sources