Results 141 to 150 of about 6,832 (204)

ROLE OF PEPTIDYLARGININE DEIMINASE AND NEUTROPHIL EXTRACELLULAR TRAPS IN INJURIES: FUTURE NOVEL DIAGNOSTICS AND THERAPEUTIC TARGETS. [PDF]

Shock, 2023
Ho JW, Quan C, Gauger MA, Alam HB, Li Y.
europepmc   +1 more source

Neutrophil extracellular traps and peptidylarginine deiminase 4-mediated inflammasome activation link diabetes to cardiorenal injury and heart failure. [PDF]

Eur Heart J
Schommer N, Gendron N, Krauel K, Van Bruggen S, Jarrot PA, Maier A, Chan W, Langer HF, Duerschmied D, Westermann D, Klingel K, Wagner DD, Heger LA.   +12 more
europepmc   +1 more source

Novel Macrocyclic Peptidylarginine Deiminase Type 4 (PAD4) Inhibitors. [PDF]

ACS Med Chem Lett, 2022
Sabnis RW.
europepmc   +1 more source

Relative Expression of Peptidylarginine Deiminase 2 and Sex Steroid Receptors in XX and XY Mouse Placenta. [PDF]

Int J Mol Sci
Wewer A, Bennitt A, Hinners E, Helmich M, Schnepp N, Pitcher S, Parsons AM, Bouma GJ.   +7 more
europepmc   +1 more source

Heavy Chain Constant Region Usage in Antibodies to Peptidylarginine Deiminase 4 as a Marker of Disease Subsets in Rheumatoid Arthritis. [PDF]

Arthritis Rheumatol, 2022
Gómez-Bañuelos E, Shi J, Wang H, Danila MI, Bridges SL, Giles JT, Sims GP, Andrade F, Darrah E.   +8 more
europepmc   +1 more source

Serum antibodies to peptidylarginine deiminase-4 in rheumatoid arthritis associated-interstitial lung disease are associated with decreased lung fibrosis and improved survival. [PDF]

Am J Med Sci, 2023
Wilson TM, Solomon JJ, Humphries SM, Swigris JJ, Ahmed F, Wang H, Darrah E, Demoruelle MK.   +7 more
europepmc   +1 more source

Peptidylarginine Deiminase (PAD) Inhibitor Optimization through Displacement of a Trapped Water Molecule. [PDF]

ACS Med Chem Lett
Schnute ME, Chinigo GM, Futatsugi K, Yamaguchi M, Bagley SW, Banker ME, Chang JS, Chen MZ, Choi WY, Corbett MS, Drozda SE, Ebner DC, Garcia-Irizarry C, Hicklin R, Hoy S, Jiao W, Kortum S, Lee KL, Limburg DC, Lovering F, Moreno A, Mousseau JJ, Pan S, Parikh MD, Pelker JW, Ramsey S, Reilly U, Rescourio G, Schmitt DC, Simpson B, Skrzypek GJ, Smaltz DJ, Taylor AP, Torella R, Trujillo JI, Vajdos FF, Wepy JA, Wright SW, Blakemore DC, Vincent F, Clerin VM.   +40 more
europepmc   +1 more source

Peptidylarginine Deiminase 4 Deficiency Suppresses Neutrophil Extracellular Trap Formation and Ameliorates Elastase-Induced Emphysema in Mouse Lung. [PDF]

Int J Mol Sci
Katsumata M, Ikari J, Urano A, Suzuki E, Kugou K, Hasegawa Y, Tatsumi K, Suzuki T.   +7 more
europepmc   +1 more source

Isoform-Selective PAD2/PAD4 Substrates with Unnatural Amino Acids Enable Cellular Peptidylarginine Deiminase Activity Profiling and Reveal Vimentin Citrullination Effects in Macrophages. [PDF]

Biochemistry
Gorzeń O, Mikołajczyk-Martinez A, Mamun AA, Horbach N, Severynovska O, Bereta G, Bielecka E, Mydel P, Drąg M, Kantyka T, Poręba M.   +10 more
europepmc   +1 more source

A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulation

, 2023
Bertran MT, Walmsley R, Cummings T, Valle Aramburu I, Benton DJ, Assalaarachchi J, Chasampalioti M, Swanton T, Joshi D, Federico S, Okkenhaug H, Yu L, Oxley D, Walker S, Papayannopoulos V, Suga H, Christophorou MA, Walport LJ.   +17 more
europepmc   +1 more source