Results 171 to 180 of about 6,832 (204)

Immunohistochemical localization of peptidylarginine deiminase in the rat brain

Journal of Chemical Neuroanatomy, 1992
The enzyme peptidylarginine deiminase is responsible for the post-translational modification of certain proteins by catalysing the deimination of arginine residues to citrullines. Recently, peptidylarginine deiminase has been purified from rat skeletal muscle and its primary structure determined by molecular cloning.
S R, Vincent, E, Leung, K, Watanabe
openaire   +2 more sources

Immunocytochemical localization of peptidylarginine deiminase in human eosinophils and neutrophils

Journal of Leukocyte Biology, 2001
AbstractPeptidylarginine deiminase, registered as PAD V in the DDBJ/GenBank/EMBL data banks, is expressed in HL-60 cells differentiated into granulocytes or monocytes. We analyzed PAD activities in density-fractionated human peripheral blood cell fractions. PAD activity with similar substrate specificity to that of PAD V was found in the eosinophil and
H, Asaga, K, Nakashima, T, Senshu, A, Ishigami, M, Yamada   +4 more
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Increased peptidylarginine deiminase type II in hypoxic astrocytes

Biochemical and Biophysical Research Communications, 2004
Peptidylarginine deiminase type II (PAD 2) is the primary enzyme responsible for conversion of protein bound arginine to citrulline in the central nervous system. Evidence suggests that glial fibrillary acidic protein (GFAP), the main intermediate filament in astrocytes, is deiminated, but not much is known regarding factors that control this enzymatic
Thiagarajan, Sambandam, Maria, Belousova, Mary Ann, Accaviti-Loper, Carmelo, Blanquicett, Vincenzo, Guercello, Reinout, Raijmakers, Anthony P, Nicholas   +6 more
openaire   +2 more sources

Immunohistochemical Demonstration of Peptidylarginine Deiminase in Human Sweat Glands

The American Journal of Dermatopathology, 1990
Human skin is known to contain protein-bound citrulline. This is the product of enzymatic deimination of arginine residues catalyzed by peptidylarginine deiminase. We probed frozen sections of human skin with a rabbit antiserum raised to rat skeletal muscle peptidylarginine deiminase using the avidin-biotin-peroxidase complex technique.
Y, Urano, K, Watanabe, A, Sakaki, S, Arase, Y, Watanabe, F, Shigemi, K, Takeda, K, Akiyama, T, Senshu   +8 more
openaire   +2 more sources

Transcriptional regulation of peptidylarginine deiminase expression in human keratinocytes

Journal of Dermatological Science, 2009
Peptidylarginine deiminase (PAD, EC 3.5.3.15) enzyme catalyzes the conversion of arginine residues to citrulline residues in the presence of calcium ion, which is an elaborate post-translational modification on the target protein. Recently, five isoforms have been identified in mammals.
Shibo, Ying, Sijun, Dong, Akira, Kawada, Toshio, Kojima, Stéphane, Chavanas, Marie-Claire, Méchin, Véronique, Adoue, Guy, Serre, Michel, Simon, Hidenari, Takahara   +9 more
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INHIBITORS OF PEPTIDYLARGININE DEIMINASES

2022
BYUN DANIEL H, CANALES EDA Y, DEBIEN LAURENT P, JANSA PETR, LEE RICK A, LOYER-DREW JENNIFER A, PERREAULT STEPHANE, PYUN HYUNG-JUNG, SAITO ROLAND D, SANGI MICHAEL S, SCHRIER ADAM J, SHATSKIKH MARINA E, TAYLOR JAMES G, TREIBERG JENNIFER A, VAN VELDHUIZEN JOSHUA J, XU LIANHONG   +15 more
openaire   +5 more sources

Role of Peptidylarginine Deiminase 4 in Central Nervous System Diseases

Molecular Neurobiology, 2023
Yanming Wang, Lai Wang
exaly  

Peptidylarginine Deiminases in Skin Biology

2009
Michel Simon, Stéphane Chavanas, Guy Serre, Hidenari Takahara   +3 more
openaire   +1 more source

Peptidylarginine Deiminase Enzymes

2014
Sunish Mohanan, Scott Coonrod
openaire   +1 more source

[Biochemistry of peptidylarginine deiminase].

Seikagaku. The Journal of Japanese Biochemical Society, 1989
H, Takahara, K, Sugawara
openaire   +1 more source