Results 91 to 100 of about 11,623 (233)

Biomarkers in patients with clinical signs of mild cognitive impairment or mild Alzheimer's disease but without amyloid deposits on positron emission tomography: Results from Bio‐Hermes Study participants

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) study participants may present with cognitive impairment who do not have brain amyloid deposits (Aβ−). Identifying predictive biomarkers for non‐amyloid‐related CI may provide better screening tests for trials seeking only CI Aβ+ participants and new therapy targets.
Richard C. Mohs, Douglas W. Beauregard, Lynne Hughes, Cyndy B. Cordell, Allan I. Levey, Saima Rathore, Nicholas T. Seyfried, Erik C. B. Johnson, Jessie Nicodemus‐Johnson, Joshua Christensen, Robin Wolz, John Dwyer   +11 more
wiley   +1 more source

Relationship Between Nasal Trigeminal Receptor Expression and Trigeminal Sensitivity

OTO Open, Volume 10, Issue 1, January-March 2026.
Abstract An intact intranasal trigeminal function is crucial for chemosensory and somatosensory perception, environmental irritation detection, and triggering protective reflexes. Accurately assessing intranasal trigeminal function is thus essential. Since transient receptor potential (TRP) channels' activation mediates this function, their expression ...
Akshita Joshi, Yiling Mai, Susanne Füssel, Thomas Hummel   +3 more
wiley   +1 more source

Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells [PDF]

, 2017
Wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control.
Ant, Thomas H., Charles, Philip D., Dowle, Adam A., Geoghegan, Vincent, Hester, Svenja, Larson, Tony, Rainey, Stephanie M., Sinkins, Steven P., Stainton, Kirsty, Thomas, Benjamin   +9 more
core   +3 more sources

Astrocytic responses to binge ethanol in male and female mice: An examination of astrocytic glutamate transporters and density changes in the dorsal hippocampus

Alcohol, Clinical and Experimental Research, Volume 50, Issue 1, January 2026.
The current work tested the hypothesis that sex differences in alcohol's effects are mediated by astrocytes. Using immunohistochemistry, qRT‐PCR, and ELISAs, we found that nondependent, binge‐like alcohol‐induced increases in hippocampal astrocyte density were more robust in females.
Candace Swepson, DaQuan R. Mebane, Diego Correia, Esohe H. Imafidon, Christopher P. Trevisani, James Nelson, S. Alex Marshall   +6 more
wiley   +1 more source

Quantitative proteomic analysis of sphere-forming stem-like oral cancer cells. [PDF]

, 2013
IntroductionThe purpose of this study is to identify target proteins that may play important functional roles in oral cancer stem-like cells (CSCs) using mass spectrometry-based quantitative proteomics.MethodsSphere-formation assays were performed on ...
Feng, Sizhe, Hu, Shen, Liu, Xiaojun, Misuno, Kaori   +3 more
core   +1 more source

ANGPTL8 is upregulated in subcutaneous adipose tissue at early term after bariatric surgery in patients living with obesity

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Bariatric surgery induces early immunological and transcriptomic modulations in subcutaneous adipose tissue, suggesting a transient pro‐inflammatory state and tissue remodeling process in patients living with obesity. ANGPTL8 could play a role in improving metabolic homeostasis at early‐term after bariatric surgery offering new insights into adipose ...
Ester Martínez Negro, Pablo Fernández‐García, Marina Martin‐Taboada, Andrea Soria‐Gondek, Daniela Rodríguez Marín, Patricia Cifuentes Pérez, Sagrario Martínez Cortijo, Mariano Álvarez Antolinez, Inmaculada Mora, Laura Martínez, Manuel Ros, Francesc Villarroya, Rubén Cereijo, David Sánchez‐Infantes, Patricia Corrales   +14 more
wiley   +1 more source

Research progress of the impact of Pin1 on the pathogenesis of Alzheimer's disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
Peptidyl-prolyl cis/trans isomerase (Pin1) has been identified as an important factor that can affect many neurodegenerative diseases as well as neoplasms.
Wei LI, Shi-fu XIAO
doaj  

Expresión diferencial de genes en Pyropia columbina (Bangiales, Rhodophyta) bajo hidratación y desecación natural [PDF]

, 2013
Indexación: Web of Science; Scielo.RESUMEN. En Zonas Costeras rocosas, la desecación es gatillada porción Cambios Diarios en los Niveles de marea, y la Evidencia indica experimental de Me Distribución de las algas en la zona intermareal no está ...
Contreras-Porcia, Loretto, Correa, Juan A., Fierro, Camila, Flores-Molina, María Rosa, Guajardo, Eduardo, Kube, Michael, Lovazzano, Carlos, López-Cristoffanini, Camilo, Núñez, Alejandra, Reinhardt, Richard, Thomas, Daniela   +10 more
core  

The stability of mRNA influences the temporal order of the induction of genes encoding inflammatory molecules [PDF]

, 2009
The inflammatory response plays out over time in a reproducible and organized way after an initiating stimulus. Here we show that genes activated in cultured mouse fibroblasts in response to the cytokine tumor necrosis factor could be categorized into ...
Baltimore, David, Hao, Shengli
core   +2 more sources

A guide to building the matrisome interactome: from computational predictions to experimental validation

The FEBS Journal, Volume 293, Issue 1, Page 42-70, January 2026.
This guide proposes a roadmap combining state‐of‐the‐art computational and experimental approaches (including biophysical, biochemical, and imaging techniques) to identify, characterize, and contextualize extracellular matrix (ECM) protein interactions.
Leanna Leverton, Amanpreet Kaur Bains, Ikram Isa, Sylvie Ricard‐Blum, Alexandra Naba   +4 more
wiley   +1 more source