Results 101 to 110 of about 11,623 (233)
Skin malformations in a neonatal foal tested homozygous positive for Warmblood Fragile Foal Syndrome [PDF]
, 2015 BACKGROUND: Skin malformations that resembled manifestations of Ehlers-Danlos-Syndrome were described in a variety of domestic animals during the last century as cutis hyperelastica, hyperelastosis cutis, dermatosparaxis, dermal/collagen dysplasia ...
Bleul, Ulrich +4 more
core +3 more sources
Physiological Reports, Volume 14, Issue 2, January 2026.Extracellular acidity and ATP modify electrophysiological profile in human cumulus cell subpopulations, characterized by differential functional expression of TRPM5‐like, BKCa and KV1.5 currents. Abstract Cumulus cells (CCs), derived from granulosa cells, play a key role in supporting oocyte maturation and development through bidirectional ...
Andrea Biagini +6 more
wiley +1 more source
Proteomics analysis of normal and senescent NG108-15 cells: GRP78 plays a negative role in cisplatin-induced senescence in the NG108-15 cell line. [PDF]
PLoS ONE, 2014 Accelerated senescence (ACS) leading to proliferative arrest is a physiological mechanism of the DNA damage response that occurs during tumor therapy. Our experiment was designed to detect unknown genes that may play important roles in cisplatin-induced ...
Wei Li +9 more
doaj +1 more source
A conserved set of maternal genes? Insights from a molluscan transcriptome [PDF]
, 2014 The early animal embryo is entirely reliant on maternal gene products for a ‘jump-start’ that transforms a transcriptionally inactive embryo into a fully functioning zygote.
Blaxter, Mark L. +4 more
core +4 more sources
Interaction Between Photoperiod and Sex on Hepatic Lipid Homeostasis in Rats Fed an Obesogenic Diet
The FASEB Journal, Volume 39, Issue 23, 15 December 2025.Male and female Fischer 344 rats were fed a cafeteria (CAF) diet for 11 weeks and exposed to long (L18, 18 h of light per day) or short (L6, 6 h of light per day) photoperiods for 8 weeks. Photoperiod and sex influenced hepatic steatosis, plasmatic and hepatic lipid levels, and hepatic lipid handling, showing sex‐specific metabolic responses to ...
Saioa Gómez‐Roncal +6 more
wiley +1 more source
Neoadjuvant sipuleucel-T induces both Th1 activation and immune regulation in localized prostate cancer. [PDF]
, 2019 Sipuleucel-T is the only FDA-approved immunotherapy for metastatic castration-resistant prostate cancer. The mechanism by which this treatment improves survival is not fully understood.
Chan, Stephen +6 more
core
Structural and biochemical insights of CypA and AIF interaction [PDF]
, 2017 The Cyclophilin A (CypA)/Apoptosis Inducing Factor (AIF) complex is implicated in the DNA degradation in response to various cellular stress conditions, such as oxidative stress, cerebral hypoxia-ischemia and traumatic brain injury.
Caporale, Andrea +10 more
core +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.The graphical abstract delineates the mechanisms by which acupuncture mitigates the effects of hemorrhagic stroke through the modulation of glial cells. Central to these mechanisms are APOE‐TREM2‐mediated microglial activation, astrocyte‐mediated neuroprotection, and oligodendrocyte‐driven myelination, which collectively enhance functional recovery ...
Chen Ruan +10 more
wiley +1 more source
Cell Death Discovery, 2022 Sorafenib is a classical targeted drug for the treatment of advanced hepatocellular carcinoma (HCC), but intrinsic resistance severely limited its therapeutic effects.
Li Li +5 more
doaj +1 more source
Soluble isoforms of vascular endothelial growth factor are predictors of response to sunitinib in metastatic renal cell carcinomas. [PDF]
, 2010 International audienceBACKGROUND: Angiogenesis is the target of several agents in the treatment of malignancies, including renal cell carcinoma (RCC). There is a real need for surrogate biomarkers that can predict selection of patients who may benefit ...
Paule, Bernard +11 more
core +3 more sources