Results 161 to 170 of about 5,562 (217)

A Novel Peptoid Hybrid of Alpha-Calcitonin Gene-Related Peptide (α-CGRP) Ameliorates Cardiac Remodeling in Pressure Overload-Induced Heart Failure. [PDF]

Cells
Deloach S, Kumar A, Ruggiero E, Ball R, Gleason K, Kubinak J, DiPette DJ, Potts JD.   +7 more
europepmc   +1 more source

In Vivo Efficacy of a Macrocyclic Peptoid-Peptide Hybrid That Selectively Modulates the Beta-Catenin/TCF Interaction to Inhibit Prostate Cancer. [PDF]

Prostate
Habault J, Franco JL, Ha S, Schneider JA, Voisin M, Wise DR, Wong KK, Garabedian MJ, Kirshenbaum K, Logan SK.   +9 more
europepmc   +1 more source

Discovery of a Peptoid-Based Nanoparticle Platform for Therapeutic mRNA Delivery via Diverse Library Clustering and Structural Parametrization. [PDF]

ACS Nano
Webster ER, Peck NE, Echeverri JD, Gholizadeh S, Tang WL, Woo R, Sharma A, Liu W, Rae CS, Sallets A, Adusumilli G, Gunasekaran K, Haabeth OAW, Leong M, Zuckermann RN, Deutsch S, McKinlay CJ.   +16 more
europepmc   +1 more source

In Situ Forming, Enzyme-Responsive Peptoid-Peptide Hydrogels: An Advanced Long-Acting Injectable Drug Delivery System. [PDF]

J Am Chem Soc
Coulter SM, Pentlavalli S, An Y, Vora LK, Cross ER, Moore JV, Sun H, Schweins R, McCarthy HO, Laverty G.   +9 more
europepmc   +1 more source

An intramolecular cobalt-peptoid complex as an efficient electrocatalyst for water oxidation at low overpotential. [PDF]

Chem Sci
Pahar S, Maayan G.
europepmc   +1 more source

Rationally Designed Peptoid Inhibitors of Amyloid-β Oligomerization. [PDF]

Chembiochem
Waugh ML, Wolf LM, Moore KA, Servoss SL, Moss MA.   +4 more
europepmc   +1 more source

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Peptoid Atropisomers

Journal of the American Chemical Society, 2011
We report the isolation of N-aryl peptoid oligomers that adopt chiral folds, despite the absence of chiral centers. Peptoid monomers incorporating ortho-substituted N-aryl side chains are identified that exhibit axial chirality. We observe significant energy barriers to rotation about the stereogenic carbon-nitrogen bond, allowing chromatographic ...
Bishwajit Paul, P Douglas Renfrew, Neel H Shah   +2 more
exaly   +3 more sources

Cyclic Peptoids

Journal of the American Chemical Society, 2007
Foldamers are an intriguing family of biomimetic oligomers that exhibit a propensity to adopt stable secondary structures. N-Substituted glycine oligomers, or "peptoids", are a prototypical example of these foldamer systems and are known to form a helix resembling that of polyproline type I.
Sung Bin Y, Shin, Barney, Yoo, Louis J, Todaro, Kent, Kirshenbaum   +3 more
openaire   +2 more sources

Mitochondria-Targeting Peptoids

Bioconjugate Chemistry, 2018
Mitochondria-specific delivery methods offer a valuable tool for studying mitochondria-related diseases and provide breakthroughs in therapeutic development. Although several small-molecule and peptide-based transporters have been developed, peptoids, proteolysis-resistant peptidomimetics, are a promising alternative to current approaches.
Ho Yeon Nam, Jong-Ah Hong, Jieun Choi, Seungheon Shin, Steve K. Cho, Jiwon Seo, Jiyoun Lee   +6 more
openaire   +2 more sources

Systematic conformational investigations of peptoids and peptoid–peptide chimeras

Peptide Science, 2011
AbstractPeptoids are originally defined as N‐substituted oligoglycine derivatives, and in a broader definition as N‐substituted peptides (peptoid–peptide chimeras). Both types were systematically investigated by force field calculations. The Merck MMFF and YASARA2 force fields were shown to be, among others, the most suitable ones for conformational ...
Wolfgang, Brandt, Thomas, Herberg, Ludger, Wessjohann   +2 more
openaire   +2 more sources