Results 151 to 160 of about 3,952 (212)

Computational design of functional random heteropolymers through atomistic simulations. [PDF]

PLoS One
Jin T, Lung CS, Xu T, Coley CW, Alexander-Katz A.   +4 more
europepmc   +1 more source

Sequence-defined peptoids <i>via</i> iterative exponential growth. [PDF]

Chem Sci
Clapperton AM, Hood C, Tran H.
europepmc   +1 more source

Tunable hydrogel networks by varying secondary structures of hydrophilic peptoids provide viable 3D cell culture platforms for hMSCs.

Biomater Sci
Pineda-Hernandez A, Castilla-Casadiego DA, Morton LD, Giordano-Nguyen SA, Halwachs KN, Rosales AM.   +5 more
europepmc   +1 more source

Targeting intracellular of populations Pseudomonas aeruginosa with peptide-mimetic therapies: individual efficacy and synergistic rescue of obsolete antibiotics

Burger ML, Doyle R, Lin JS, Barron AE, Moule MG.   +4 more
europepmc   +1 more source

Systematic conformational investigations of peptoids and peptoid–peptide chimeras

Peptide Science, 2011
AbstractPeptoids are originally defined as N‐substituted oligoglycine derivatives, and in a broader definition as N‐substituted peptides (peptoid–peptide chimeras). Both types were systematically investigated by force field calculations. The Merck MMFF and YASARA2 force fields were shown to be, among others, the most suitable ones for conformational ...
Wolfgang, Brandt, Thomas, Herberg, Ludger, Wessjohann   +2 more
core   +6 more sources

Porphyrin–Peptoid Conjugates: Face-to-Face Display of Porphyrins on Peptoid Helices

Organic Letters, 2013
Distance, orientation, and number controlled porphyrin-peptoid conjugates (PPCs) were efficiently synthesized. Cofacial (1, 2, and 4), slipped-cofacial (3), and unstructured (5) arrangements of porphyrins provided distinct optical and electronic properties characterized by UV-vis and circular dichroism spectroscopy.
Boyeong, Kang, Solchan, Chung, Young Deok, Ahn, Jiyoun, Lee, Jiwon, Seo   +4 more
openaire   +3 more sources

A Peptoid with Extended Shape in Water [PDF]

Journal of the American Chemical Society, 2019
The term "peptoids" was introduced decades ago to describe peptide analogues that exhibit better physicochemical and pharmacokinetic properties than peptides. Oligo(N-substituted glycine) (oligo-NSG) was previously proposed as a peptoid due to its high proteolytic resistance and membrane permeability.
Jumpei Morimoto, Yasuhiro Fukuda, Daisuke Kuroda, Takumu Watanabe, Fumihiko Yoshida, Mizue Asada, Toshikazu Nakamura, Akinobu Senoo, Satoru Nagatoishi, Kouhei Tsumoto, Shinsuke Sando   +10 more
openaire   +4 more sources

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Synthesis of Nucleobase-Functionalized β-Peptoids and β-Peptoid Hybrids

Tetrahedron Letters, 2006
Abstract The solid-phase synthesis of a new class of nucleobase-modified peptide-mimetic oligomers is described. β-Peptoids and β-peptoid hybrids bearing thymine on the side chain are prepared from N-Fmoc-N-[2-(thymin-1-yl)ethyl]-β-alanine.
Eduard Bardají, Lidia Feliu, Marta Planas Grabuleda   +2 more
exaly   +2 more sources

Cyclic Peptoids

Journal of the American Chemical Society, 2007
Foldamers are an intriguing family of biomimetic oligomers that exhibit a propensity to adopt stable secondary structures. N-Substituted glycine oligomers, or "peptoids", are a prototypical example of these foldamer systems and are known to form a helix resembling that of polyproline type I.
Sung Bin Y, Shin, Barney, Yoo, Louis J, Todaro, Kent, Kirshenbaum   +3 more
openaire   +2 more sources