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Peptoids and Peptide–Peptoid Hybrid Biopolymers as Peptidomimetics
2013Peptoids (oligomers of N-substituted glycine residues) and peptide-peptoid hybrid polymers (peptomers) are interesting classes of compounds mimicking structure and function of biologically active peptides. The oligomeric peptidomimetics such as peptoids are particularly important compounds since they provide access to an enormous molecular diversity ...
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Biopolymers, 2019
AbstractA review of molecular tools and sensors assembled onN‐substituted glycine, or α‐peptoid, oligomers between 2013 and November 2018 with the following sections: (a) Peptoids as crystal growth modifiers, (b) Peptoids as catalysts, (c) Ion and molecule sequestration and transport, (d) Peptoid sensors, (e) Macromolecule recognition, (f) Cellular ...
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AbstractA review of molecular tools and sensors assembled onN‐substituted glycine, or α‐peptoid, oligomers between 2013 and November 2018 with the following sections: (a) Peptoids as crystal growth modifiers, (b) Peptoids as catalysts, (c) Ion and molecule sequestration and transport, (d) Peptoid sensors, (e) Macromolecule recognition, (f) Cellular ...
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A fluorescent peptoid pH‐sensor
Peptide Science, 2013ABSTRACTPeptoids, N‐substituted glycine oligomers, can adopt stable three‐dimensional structures and have found diverse application as peptide surrogates and as nanomaterials. In this report, we have expanded peptoid function to include pH sensing by coupling pH‐induced peptoid conformational changes with fluorescence intensity changes.
Amelia A, Fuller +2 more
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Peptoids as endothelin receptor antagonists
Bioorganic & Medicinal Chemistry Letters, 2001A series of new peptoids as endothelin receptor antagonists has been synthesized. Screening them for their ability to bind with endothelin receptors (ET(A) and ET(B)) competitively in the presence of (125I) endothelin led to the discovery of compounds as possible leads with IC50s in the low micromolar concentrations.
F, Dasgupta +5 more
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Functionalized Helical β-Peptoids
The Journal of Organic Chemistry, 2019Peptidomimetic foldamers adopting well-defined three-dimensional structures while being stable toward proteolysis are of interest in biomedical research, chemical biology, and biomimetic materials science. Despite their backbone flexibility, β-peptoids containing N-( S)-1-(1-naphthyl)ethyl ( Ns1npe) side chains can fold into unique triangular prism ...
Isabelle Wellhöfer +5 more
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Design and synthesis of peptoid nanomaterial -peptoid nanosheets
2021Infections caused by biofilms on abiotic surfaces are among the most common infections. Surface engineering for antimicrobial purposes has been implemented as a potential strategy to avoid biofilm formation. However, despite the availability of a variety of nanotechnologies for synthesis and functionalization of biological nanomaterials for anti ...
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Biomimetic Peptoid-Assisted Fabrication of Antibiofouling Thin-Film Composite Membranes
Chemical Engineering Journal, 2023Jung-Hyun Lee, Sung-Joon Park
exaly