Results 121 to 130 of about 1,025,819 (311)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Adaptive design of delta sigma modulators

open access: yes, 2006
In this thesis, a genetic algorithm based on differential evolution (DE) is used to generate delta sigma modulator (DSM) noise transfer functions (NTFs). These NTFs outperform those generated by an iterative approach described by Schreier and implemented
Lull, Gregory Kenneth
core   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Examen de l’aptitude à la reproduction chez le bélier et le bouc

open access: yesRevue Marocaine des Sciences Agronomiques et Vétérinaires, 2018
L’examen de l’aptitude à la reproduction (EAR) du mâle est une composante importante de l’élevage des petits ruminants. L’EAR est mieux réalisée 2 mois avant la saison de reproduction.
A. TIBARY, R. BOUKHLIQ, K. EL ALLALI
doaj  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Leslislating in the Face of New Technology: Copyright Laws for the Digital Age [PDF]

open access: yes, 1996
This Note discusses the agendas and proposals of different countries with respect to copyright regulation in the digital age. Part I discusses the present state of copyright law in the United States, the United Kingdom, and the European Community. Part I
Morano, Michael F.
core   +1 more source

Performances de reproduction de l'élevage canin en France

open access: yes, 2015
Les données enregistrées par 5667 éleveurs dans un logiciel privé sur 46393 périodes de chaleur de 27221 chiennes de 248 races et 204537 chiots ont permis de décrire les performances de l'élevage canin français. Le taux de gestation par cycle était de 87,8%, 6,8% des chiennes gravides ont avorté.
openaire   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Nesterov Acceleration of Alternating Least Squares for Canonical Tensor Decomposition: Momentum Step Size Selection and Restart Mechanisms

open access: yes, 2019
We present Nesterov-type acceleration techniques for Alternating Least Squares (ALS) methods applied to canonical tensor decomposition. While Nesterov acceleration turns gradient descent into an optimal first-order method for convex problems by adding a ...
De Sterck, Hans, Mitchell, Drew, Ye, Nan
core   +1 more source

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