Results 91 to 100 of about 2,525 (205)
Genome sequencing and analysis of a type A Clostridium perfringens isolate from a case of bovine clostridial abomasitis. [PDF]
Clostridium perfringens is a common inhabitant of the avian and mammalian gastrointestinal tracts and can behave commensally or pathogenically. Some enteric diseases caused by type A C.
Victoria J Nowell +5 more
doaj +1 more source
Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins [PDF]
Permeabilization of the plasma membrane represents an important threat for any cell, since it compromises its viability by disrupting cell homeostasis.
Etxaniz Iriondo, Asier +3 more
core +3 more sources
Upon the invasion of Listeria monocytogenes into a host cell, the primary virulence factor, listeriolysin O (LLO), secreted by the bacterium, has the capacity to breach the mitochondrial membrane, thereby gaining access to the inner mitochondrial membrane (IMM). The interaction between LLO and Mic60 can induce significant changes in the architecture of
Changyong Cheng +13 more
wiley +1 more source
The largest superfamily of bacterial virulence factors is pore-forming toxins (PFTs). PFTs are secreted by both pathogenic and non-pathogenic bacteria. PFTs sometimes kill or induce pro-pathogen signaling in mammalian cells, all primarily through plasma ...
Sucharit Ray +2 more
doaj +1 more source
An upstream regulatory sequence stimulates expression of the perfringolysin O gene of Clostridium perfringens [PDF]
The structural gene for perfringolysin O (pfoA), a thiol-activated hemolysin of Clostridium perfringens, was cloned into Escherichia coli JM109 on a 4.6-kilobase (kb) EcoRI-NdeI fragment which contained the 1.7-kb pfoA gene and an upstream 2.9-kb region. An E.
T, Shimizu +3 more
openaire +2 more sources
Matching Together Living Cells and Prototissues: Will There Be Chemistry?
In the field of tissue engineering, the combination of synthetic and living tissues could be the turning point. In this work we review examples of hybrid protocell/living cell and prototissue/living cell systems, focusing on the chemistry that makes the integration between non‐living and living matter efficient.
Stefano Valente +5 more
wiley +1 more source
Assessment of Brown Adipocyte Thermogenic Function by High-throughput Respirometry
Brown adipose tissue (BAT) has the unique ability to dramatically increase mitochondrial uncoupled fuel oxidation for thermogenesis in response to adrenergic stimulation.
Kiana Mahdaviani +2 more
doaj +1 more source
Cellular IP6 Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP6 Are Attenuated for Infection and Replication [PDF]
Summary: HIV-1 hijacks host proteins to promote infection. Here we show that HIV is also dependent upon the host metabolite inositol hexakisphosphate (IP6) for viral production and primary cell replication.
Böcking, Till +10 more
core +3 more sources
Our study investigates the influence of extracellular vesicles, released by two bacterial species of the human cervicovaginal microbiome, on the infection by Trichomonas vaginalis. We described species‐specific protein cargoes of these vesicles matching the expected contribution of the bacteria to this biome.
Anastasiia Artuyants +4 more
wiley +1 more source
By producing alpha toxin (PLC) and perfringolysin O (PFO), Clostridium perfringens type A strains are the most common cause of traumatic gas gangrene. C. perfringens cannot synthesize branched-chain amino acids (BCAAs), so BCAA transporters are essential
Jihong Li +3 more
doaj +1 more source

