Results 91 to 100 of about 2,525 (205)

Genome sequencing and analysis of a type A Clostridium perfringens isolate from a case of bovine clostridial abomasitis. [PDF]

open access: yesPLoS ONE, 2012
Clostridium perfringens is a common inhabitant of the avian and mammalian gastrointestinal tracts and can behave commensally or pathogenically. Some enteric diseases caused by type A C.
Victoria J Nowell   +5 more
doaj   +1 more source

Membrane Repair Mechanisms against Permeabilization by Pore-Forming Toxins [PDF]

open access: yes, 2018
Permeabilization of the plasma membrane represents an important threat for any cell, since it compromises its viability by disrupting cell homeostasis.
Etxaniz Iriondo, Asier   +3 more
core   +3 more sources

The MICOS Complex Subunit Mic60 is Hijacked by Intracellular Bacteria to Manipulate Mitochondrial Dynamics and Promote Bacterial Pathogenicity

open access: yesAdvanced Science, Volume 11, Issue 46, December 11, 2024.
Upon the invasion of Listeria monocytogenes into a host cell, the primary virulence factor, listeriolysin O (LLO), secreted by the bacterium, has the capacity to breach the mitochondrial membrane, thereby gaining access to the inner mitochondrial membrane (IMM). The interaction between LLO and Mic60 can induce significant changes in the architecture of
Changyong Cheng   +13 more
wiley   +1 more source

Multiple Parameters Beyond Lipid Binding Affinity Drive Cytotoxicity of Cholesterol-Dependent Cytolysins

open access: yesToxins, 2018
The largest superfamily of bacterial virulence factors is pore-forming toxins (PFTs). PFTs are secreted by both pathogenic and non-pathogenic bacteria. PFTs sometimes kill or induce pro-pathogen signaling in mammalian cells, all primarily through plasma ...
Sucharit Ray   +2 more
doaj   +1 more source

An upstream regulatory sequence stimulates expression of the perfringolysin O gene of Clostridium perfringens [PDF]

open access: yesInfection and Immunity, 1991
The structural gene for perfringolysin O (pfoA), a thiol-activated hemolysin of Clostridium perfringens, was cloned into Escherichia coli JM109 on a 4.6-kilobase (kb) EcoRI-NdeI fragment which contained the 1.7-kb pfoA gene and an upstream 2.9-kb region. An E.
T, Shimizu   +3 more
openaire   +2 more sources

Matching Together Living Cells and Prototissues: Will There Be Chemistry?

open access: yesChemBioChem, Volume 25, Issue 18, September 16, 2024.
In the field of tissue engineering, the combination of synthetic and living tissues could be the turning point. In this work we review examples of hybrid protocell/living cell and prototissue/living cell systems, focusing on the chemistry that makes the integration between non‐living and living matter efficient.
Stefano Valente   +5 more
wiley   +1 more source

Assessment of Brown Adipocyte Thermogenic Function by High-throughput Respirometry

open access: yesBio-Protocol, 2015
Brown adipose tissue (BAT) has the unique ability to dramatically increase mitochondrial uncoupled fuel oxidation for thermogenesis in response to adrenergic stimulation.
Kiana Mahdaviani   +2 more
doaj   +1 more source

Cellular IP6 Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP6 Are Attenuated for Infection and Replication [PDF]

open access: yes, 2019
Summary: HIV-1 hijacks host proteins to promote infection. Here we show that HIV is also dependent upon the host metabolite inositol hexakisphosphate (IP6) for viral production and primary cell replication.
Böcking, Till   +10 more
core   +3 more sources

Lactobacillus gasseri and Gardnerella vaginalis produce extracellular vesicles that contribute to the function of the vaginal microbiome and modulate host–Trichomonas vaginalis interactions

open access: yesMolecular Microbiology, Volume 122, Issue 3, Page 357-371, September 2024.
Our study investigates the influence of extracellular vesicles, released by two bacterial species of the human cervicovaginal microbiome, on the infection by Trichomonas vaginalis. We described species‐specific protein cargoes of these vesicles matching the expected contribution of the bacteria to this biome.
Anastasiia Artuyants   +4 more
wiley   +1 more source

BrnQ Branched-Chain Amino Acid Transporters Influence Toxin Production by, but Not Growth of, Clostridium perfringens Type A Strain ATCC3624

open access: yesToxins
By producing alpha toxin (PLC) and perfringolysin O (PFO), Clostridium perfringens type A strains are the most common cause of traumatic gas gangrene. C. perfringens cannot synthesize branched-chain amino acids (BCAAs), so BCAA transporters are essential
Jihong Li   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy