Results 91 to 100 of about 30,427 (250)
, 2012 (A) Mouse primary pericytes were treated with buffer, NE or Tolazoline. Cells were fixed and stained for F-actin, paxillin and nuclei. Bar = 10 µm. (B) NE increased RhoA activity in pericytes while Tolazoline inhibited it.
Shijun Wang (89455) +6 more
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Advanced Science, EarlyView.Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng +14 more
wiley +1 more source
, 2016 A. Example of AngII induced membrane potential responses of a pericyte and an endothelial cell physically associated with one another along the DVR wall (as in Fig 5A). Similar time dependent variations persisted throughout the record. Resting potentials
Thomas L. Pallone (183981) +2 more
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Advanced Science, EarlyView.Subarachnoid hemorrhage (SAH) triggers monocyte‐derived macrophage (MDM) infiltration and M1‐like polarization via Vimentin upregulation, leading to neurovascular unit disruption and cognitive dysfunction. Remote ischemic postconditioning (RIPostC) upregulates neuronal Gas6, which activates Axl on MDMs to downregulate Vimentin and drive reparative M2 ...
Yajun Zhu +14 more
wiley +1 more source
Pericyte degeneration causes white matter dysfunction in the mouse central nervous system
, 2018 Diffuse white-matter disease associated with small-vessel disease and dementia is prevalent in the elderly. The biological mechanisms, however, remain elusive.
Ralf Langen +39 more
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Pericyte actomyosin-mediated contraction at the cell-material interface can modulate the microvascular niche [PDF]
, 2009 Pericytes physically surround the capillary endothelium, contacting and communicating with associated vascular endothelial cells via cell–cell and cell–matrix contacts. Pericyte–endothelial cell interactions thus have the potential to modulate growth and
Van Vliet, Krystyn J. +5 more
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Advanced Science, EarlyView.AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang +19 more
wiley +1 more source
Lung pericyte-like cells are functional interstitial immune sentinel cells
, 2017 Pericytes are perivascular PDGF receptor-β+ (PDGFRβ+) stromal cells required for vasculogenesis and maintenance of microvascular homeostasis in many organs.
Kristen L. Mittelsteadt +10 more
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Impact of Autoimmune Demyelinating Brain Disease Sera on Pericyte Survival
, 2020 Introduction: Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterized by demyelination and brain pericyte dysfunction might be involved in MS pathogenesis Our aim was to evaluate whether the factors in serum ...
Karaaslan, Zerrin +25 more
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, 2016 Pericytes, spatially isolated contractile cells on capillaries, have been reported to control cerebral blood flow physiologically, and to limit blood flow after ischaemia by constricting capillaries and then dying. Paradoxically, a recent paper dismisses
Mishra, A +15 more
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